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Patient Preferences...
Patient Preferences for Lung Cancer Treatments: A Study Protocol for a Preference Survey Using Discrete Choice Experiment and Swing Weighting
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- Monzani, Dario (författare)
- Applied Research Division for Cognitive and Psychological Science, IEO, European Institute of Oncology IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy
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- Petrocchi, Serena (författare)
- Applied Research Division for Cognitive and Psychological Science, IEO, European Institute of Oncology IRCCS, Milan, Italy
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- Oliveri, Serena (författare)
- Applied Research Division for Cognitive and Psychological Science, IEO, European Institute of Oncology IRCCS, Milan, Italy
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- Veldwijk, Jorien (författare)
- Erasmus School of Health Policy & Management, Erasmus University Rotterdam, Rotterdam, Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands; Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium
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- Janssens, Rosanne (författare)
- Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium
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- Bailo, Luca (författare)
- Applied Research Division for Cognitive and Psychological Science, IEO, European Institute of Oncology IRCCS, Milan, Italy
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- Smith, Meredith Y. (författare)
- Alexion Pharmaceuticals, Inc., Boston, MA, United States; University of Southern California School of Pharmacy, Los Angeles, CA, United States
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- Smith, Ian (författare)
- Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands
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- Schoefs, Elise (författare)
- Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium
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- Nackaerts, Kristiaan (författare)
- Department of Respiratory Oncology, University Hospital Leuven, Leuven, Belgium
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- Vandevelde, Marie (författare)
- Department of Respiratory Oncology, University Hospital Leuven, Leuven, Belgium
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- Louis, Evelyne (författare)
- Department of Respiratory Oncology, University Hospital Leuven, Leuven, Belgium
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- Decaluwé, Herbert (författare)
- Department of Thoracic Surgery, KU Leuven, Leuven, Belgium
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- De Leyn, Paul (författare)
- Department of Thoracic Surgery, KU Leuven, Leuven, Belgium
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- Declerck, Hanne (författare)
- Department of Thoracic Surgery, KU Leuven, Leuven, Belgium
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- Katz, Eva G. (författare)
- Janssen Research and Development, LLC, Raritan, NJ, United States
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- Petrella, Francesco (författare)
- Thoracic Surgery Division, IEO, European Institute of Oncology IRCCS, Milan, Italy
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- Casiraghi, Monica (författare)
- Thoracic Surgery Division, IEO, European Institute of Oncology IRCCS, Milan, Italy
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- Durosini, Ilaria (författare)
- Applied Research Division for Cognitive and Psychological Science, IEO, European Institute of Oncology IRCCS, Milan, Italy
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- Galli, Guilia (författare)
- Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
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- Garassino, Marina Chiara (författare)
- University of Chicago Department of Medicine Section Hematology/Oncology, Chicago, IL, United States
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- de Wit, G. Ardine (författare)
- Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium
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- Pravettoni, Gabriella (författare)
- Applied Research Division for Cognitive and Psychological Science, IEO, European Institute of Oncology IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy
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- Huys, Isabelle (författare)
- Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium
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(creator_code:org_t)
- 2021-08-02
- 2021
- Engelska.
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Ingår i: Frontiers in Medicine. - : Frontiers Media SA. - 2296-858X. ; 8
- Relaterad länk:
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https://doi.org/10.3...
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https://www.frontier...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Ämnesord
Stäng
- Background: Advanced treatment options for non-small cell lung cancer (NSCLC) consist of immunotherapy, chemotherapy, or a combination of both. Decisions surrounding NSCLC can be considered as preference-sensitive because multiple treatments exist that vary in terms of mode of administration, treatment schedules, and benefit–risk profiles. As part of the IMI PREFER project, we developed a protocol for an online preference survey for NSCLC patients exploring differences in preferences according to patient characteristics (preference heterogeneity). Moreover, this study will evaluate and compare the use of two different preference elicitation methods, the discrete choice experiment (DCE) and the swing weighting (SW) task. Finally, the study explores how demographic (i.e., age, gender, and educational level) and clinical (i.e., cancer stage and line of treatment) information, health literacy, health locus of control, and quality of life may influence or explain patient preferences and the usefulness of a digital interactive tool in providing information on preference elicitation tasks according to patients.Methods: An online survey will be implemented with the aim to recruit 510 NSCLC patients in Belgium and Italy. Participants will be randomized 50:50 to first receive either the DCE or the SW. The survey will also collect information on participants' disease-related status, health locus of control, health literacy, quality of life, and perception of the educational tool.Discussion: This protocol outlines methodological and practical steps to quantitatively elicit and study patient preferences for NSCLC treatment alternatives. Results from this study will increase the understanding of which treatment aspects are most valued by NSCLC patients to inform decision-making in drug development, regulatory approval, and reimbursement. Methodologically, the comparison between the DCE and the SW task will be valuable to gain information on how these preference methods perform against each other in eliciting patient preferences. Overall, this protocol may assist researchers, drug developers, and decision-makers in designing quantitative patient preferences into decision-making along the medical product life cycle.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Samhällsfarmaci och klinisk farmaci (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Social and Clinical Pharmacy (hsv//eng)
Nyckelord
- non-small cell lung cancer
- patient preference
- discrete choice experiment
- swing weighting
- educational tool
- health literacy
- health locus of control
- quality of life
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Monzani, Dario
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Petrocchi, Seren ...
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Oliveri, Serena
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Veldwijk, Jorien
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Janssens, Rosann ...
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Bailo, Luca
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visa fler...
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Smith, Meredith ...
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Smith, Ian
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Schoefs, Elise
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Nackaerts, Krist ...
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Vandevelde, Mari ...
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Louis, Evelyne
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Decaluwé, Herber ...
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De Leyn, Paul
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Declerck, Hanne
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Katz, Eva G.
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Petrella, France ...
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Casiraghi, Monic ...
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Durosini, Ilaria
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Galli, Guilia
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Garassino, Marin ...
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de Wit, G. Ardin ...
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Pravettoni, Gabr ...
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Huys, Isabelle
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Medicinska och f ...
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Frontiers in Med ...
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