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The diagnostic chal...
The diagnostic challenge of suspicious or positive malignant urine cytology findings when cystoscopy findings are normal : an outpatient blue-light flexible cystoscopy may solve the problem
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- Andersson, Marie (författare)
- Helsingborg Hosp, Dept Urol, Charlotte Yhlensgata 10, S-25187 Helsingborg, Sweden.
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- Berger, Marthe (författare)
- Lillebelt Hosp, Dept Urol, Vejle, Denmark.
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- Zieger, Karsten (författare)
- Lillebelt Hosp, Dept Urol, Vejle, Denmark.
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- Malmström, Per-Uno (författare)
- Uppsala universitet,Urologkirurgi
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- Bläckberg, Mats (författare)
- Helsingborg Hosp, Dept Urol, Charlotte Yhlensgata 10, S-25187 Helsingborg, Sweden.
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Helsingborg Hosp, Dept Urol, Charlotte Yhlensgata 10, S-25187 Helsingborg, Sweden Lillebelt Hosp, Dept Urol, Vejle, Denmark. (creator_code:org_t)
- 2021-05-26
- 2021
- Engelska.
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Ingår i: Scandinavian journal of urology. - : Taylor & Francis. - 2168-1805 .- 2168-1813. ; 55:4, s. 263-267
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Purpose: To investigate whether outpatient blue-light flexible cystoscopy could solve the diagnostic challenge of positive or suspicious urine cytology findings despite normal white-light flexible cystoscopy results and normal findings on computerized tomography urography, in patients investigated for urothelial cancer.Material and methods: In a multicentre study, a total of 70 examinations were performed with the use of blue-light flexible cystoscopy (photodynamic diagnosis) after intravesical instillation of the fluorescence agent hexaminolevulinate. The examination started with a conventional white-light flexible cystoscopy and then the settings were switched to use blue light. Suspicious lesions were biopsied. Afterwards, the patients were interviewed regarding their experience of the examinations.Results: Bladder cancer was diagnosed in 29 out of 70 (41%) cases, among them 14/29 (48%) had malignant lesions seen only in blue light. The majority had carcinoma in situ (21/29). Normal findings were seen in 41 cases that underwent BLFC. During the further course, malignancy of the bladder was detected in six cases (9%) and malignancy of the upper urinary tract was detected in one case (1%). The majority of patients (93%) preferred the blue-light flexible cystoscopy performed at the outpatient clinic instead of the transurethral resection under general anaesthesia.Conclusion: Blue-light flexible cystoscopy at the outpatient clinic may be a useful tool to solve unclear cases of a malignant or suspicious urinary cytology suggestive of bladder cancer. The procedure was well tolerated by the patients.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
Nyckelord
- Bladder cancer
- diagnosis
- flexible cystoscopy
- PDD
- outpatient clinic
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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