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The impact of publi...
The impact of public health interventions in the Nordic countries during the first year of SARS-CoV-2 transmission and evolution
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- Duchene, Sebastian (författare)
- Univ Melbourne, Dept Microbiol & Immunol, Peter Doherty Inst Infect & Immun, Melbourne, Vic, Australia.
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- Featherstone, Leo (författare)
- Univ Melbourne, Dept Microbiol & Immunol, Peter Doherty Inst Infect & Immun, Melbourne, Vic, Australia.
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- de Blasio, Birgitte Freiesleben (författare)
- Norwegian Inst Publ Hlth, Dept Methods Dev & Analyt, Div Infect Dis Control & Environm Hlth, Oslo, Norway.;Univ Oslo, Oslo Ctr Biostat & Epidemiol, Inst Basic Med Sci, Dept Biostat, Oslo, Norway.
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- Holmes, Edward C. (författare)
- Univ Sydney, Sydney Inst Infect Dis, Sch Life & Environm Sci, Sydney, NSW, Australia.;Univ Sydney, Sch Med Sci, Sydney, NSW, Australia.
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- Bohlin, Jon (författare)
- Norwegian Inst Publ Hlth, Dept Methods Dev & Analyt, Div Infect Dis Control & Environm Hlth, Oslo, Norway.
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- Pettersson, John, 1981- (författare)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Univ Sydney, Sydney Inst Infect Dis, Sch Life & Environm Sci, Sydney, NSW, Australia.;Univ Sydney, Sch Med Sci, Sydney, NSW, Australia.,Zoonosis Science Center
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Univ Melbourne, Dept Microbiol & Immunol, Peter Doherty Inst Infect & Immun, Melbourne, Vic, Australia Norwegian Inst Publ Hlth, Dept Methods Dev & Analyt, Div Infect Dis Control & Environm Hlth, Oslo, Norway.;Univ Oslo, Oslo Ctr Biostat & Epidemiol, Inst Basic Med Sci, Dept Biostat, Oslo, Norway. (creator_code:org_t)
- European Centre for Disease Control and Prevention (ECDC), 2021
- 2021
- Engelska.
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Ingår i: Eurosurveillance. - : European Centre for Disease Control and Prevention (ECDC). - 1025-496X .- 1560-7917. ; 26:44
- Relaterad länk:
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https://doi.org/10.2...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.2...
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Abstract
Ämnesord
Stäng
- Background: Many countries have attempted to miti-gate and control COVID-19 through non-pharma-ceutical interventions, particularly with the aim of reducing population movement and contact. However, it remains unclear how the different control strategies impacted the local phylodynamics of the causative SARS-CoV-2 virus.Aim: We aimed to assess the dura-tion of chains of virus transmission within individual countries and the extent to which countries exported viruses to their geographical neighbours.Methods: We analysed complete SARS-CoV-2 genomes to infer the relative frequencies of virus importation and exportation, as well as virus transmission dynamics, in countries of northern Europe. We examined virus evolution and phylodynamics in Denmark, Finland, Iceland, Norway and Sweden during the first year of the COVID-19 pandemic.Results: The Nordic coun-tries differed markedly in the invasiveness of control strategies, which we found reflected in transmission chain dynamics. For example, Sweden, which com-pared with the other Nordic countries relied more on recommendation-based rather than legislation-based mitigation interventions, had transmission chains that were more numerous and tended to have more cases. This trend increased over the first 8 months of 2020. Together with Denmark, Sweden was a net exporter of SARS-CoV-2. Norway and Finland implemented legis-lation-based interventions; their transmission chain dynamics were in stark contrast to their neighbour-ing country Sweden.Conclusion: Sweden constituted an epidemiological and evolutionary refugium that enabled the virus to maintain active transmission and spread to other geographical locations. Our analysis reveals the utility of genomic surveillance where moni- toring of active transmission chains is a key metric.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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