Sökning: onr:"swepub:oai:DiVA.org:uu-462626" > PharmVar GeneFocus :
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 03044naa a2200517 4500 | |
001 | oai:DiVA.org:uu-462626 | |
003 | SwePub | |
008 | 211228s2021 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4626262 URI |
024 | 7 | a https://doi.org/10.1002/cpt.23332 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Sangkuhl, Katrin4 aut |
245 | 1 0 | a PharmVar GeneFocus :b CYP2C9 |
264 | c 2021-07-12 | |
264 | 1 | b John Wiley & Sons,c 2021 |
338 | a electronic2 rdacarrier | |
520 | a The Pharmacogene Variation Consortium (PharmVar) catalogues star (*) allele nomenclature for the polymorphic human CYP2C9 gene. Genetic variation within the CYP2C9 gene locus impacts the metabolism or bioactivation of many clinically important drugs, including nonsteroidal anti-inflammatory drugs, phenytoin, antidiabetic agents, and angiotensin receptor blockers. Variable CYP2C9 activity is of particular importance regarding efficacy and safety of warfarin and siponimod as indicated in their package inserts. This GeneFocus provides a comprehensive overview and summary of CYP2C9 and describes how haplotype information catalogued by PharmVar is utilized by the Pharmacogenomics Knowledgebase and the Clinical Pharmacogenetics Implementation Consortium. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Klinisk laboratoriemedicin0 (SwePub)302232 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Clinical Laboratory Medicine0 (SwePub)302232 hsv//eng |
653 | a Clinical Pharmacology | |
653 | a Klinisk farmakologi | |
700 | 1 | a Claudio-Campos, Karla4 aut |
700 | 1 | a Cavallari, Larisa H4 aut |
700 | 1 | a Agundez, Jose A G4 aut |
700 | 1 | a Whirl-Carrillo, Michelle4 aut |
700 | 1 | a Duconge, Jorge4 aut |
700 | 1 | a Del Tredici, Andria L4 aut |
700 | 1 | a Wadelius, Miau Uppsala universitet,Institutionen för medicinska vetenskaper,Science for Life Laboratory, SciLifeLab,Klinisk farmakogenomik och osteoporos, Clinical pharmacogenomics and osteoporosis4 aut0 (Swepub:uu)miawadel |
700 | 1 | a Rodrigues Botton, Mariana4 aut |
700 | 1 | a Woodahl, Erica L4 aut |
700 | 1 | a Scott, Stuart A4 aut |
700 | 1 | a Klein, Teri E4 aut |
700 | 1 | a Pratt, Victoria M4 aut |
700 | 1 | a Daly, Ann K4 aut |
700 | 1 | a Gaedigk, Andrea4 aut |
710 | 2 | a Uppsala universitetb Institutionen för medicinska vetenskaper4 org |
773 | 0 | t Clinical Pharmacology and Therapeuticsd : John Wiley & Sonsg 110:3, s. 662-676q 110:3<662-676x 0009-9236x 1532-6535 |
856 | 4 | u https://doi.org/10.1002/cpt.2333y Fulltext |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1623293/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cpt.2333 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-462626 |
856 | 4 8 | u https://doi.org/10.1002/cpt.2333 |
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