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Advances in the Sen...
Advances in the Sensing and Treatment of Wound Biofilms
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- Darvishi, Sorour (författare)
- Univ Cambridge, Dept Chem Engn & Biotechnol, Philippa Fawcett Dr, Cambridge CB3 0AS, England.;Ecole Polytech Fed Lausanne, Dept Chem & Chem Engn, CH-1951 Sion, Switzerland
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- Tavakoli, Shima (författare)
- Uppsala universitet,Polymerkemi
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- Kharaziha, Mahshid (författare)
- Isfahan Univ Technol, Dept Mat Engn, Esfahan 8415683111, Iran
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- Girault, Hubert H. (författare)
- Ecole Polytech Fed Lausanne, Dept Chem & Chem Engn, CH-1951 Sion, Switzerland
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- Kaminski, Clemens F. (författare)
- Univ Cambridge, Dept Chem Engn & Biotechnol, Philippa Fawcett Dr, Cambridge CB3 0AS, England
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- Mela, Ioanna (författare)
- Univ Cambridge, Dept Chem Engn & Biotechnol, Philippa Fawcett Dr, Cambridge CB3 0AS, England
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Univ Cambridge, Dept Chem Engn & Biotechnol, Philippa Fawcett Dr, Cambridge CB3 0AS, England;Ecole Polytech Fed Lausanne, Dept Chem & Chem Engn, CH-1951 Sion, Switzerland Polymerkemi (creator_code:org_t)
- 2022-02-03
- 2022
- Engelska.
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Ingår i: Angewandte Chemie International Edition. - : Wiley-VCH Verlagsgesellschaft. - 1433-7851 .- 1521-3773. ; 61:13
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Wound biofilms represent a particularly challenging problem in modern medicine. They are increasingly antibiotic resistant and can prevent the healing of chronic wounds. However, current treatment and diagnostic options are hampered by the complexity of the biofilm environment. In this review, we present new chemical avenues in biofilm sensors and new materials to treat wound biofilms, offering promise for better detection, chemical specificity, and biocompatibility. We briefly discuss existing methods for biofilm detection and focus on novel, sensor-based approaches that show promise for early, accurate detection of biofilm formation on wound sites and that can be translated to point-of-care settings. We then discuss technologies inspired by new materials for efficient biofilm eradication. We focus on ultrasound-induced microbubbles and nanomaterials that can both penetrate the biofilm and simultaneously carry active antimicrobials and discuss the benefits of those approaches in comparison to conventional methods.
Ämnesord
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
Nyckelord
- biofilms
- biosensors
- medicinal chemistry
- nanotechnology
- wound biofilms
Publikations- och innehållstyp
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