Sökning: onr:"swepub:oai:DiVA.org:uu-485646" > Population-Based Co...
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000 | 05426naa a2200481 4500 | |
001 | oai:DiVA.org:uu-485646 | |
003 | SwePub | |
008 | 221006s2022 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:149999543 | |
009 | oai:DiVA.org:liu-186814 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4856462 URI |
024 | 7 | a https://doi.org/10.1245/s10434-022-11922-52 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1499995432 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1868142 URI |
040 | a (SwePub)uud (SwePub)kid (SwePub)liu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Hayami, Masaruu Karolinska Univ Hosp, Dept Upper Abdominal Surg, Ctr Digest Dis, Stockholm, Sweden.;Japanese Fdn Canc Res, Canc Inst Hosp, Dept Surg Gastroenterol, Gastroenterol Ctr, Tokyo, Japan.4 aut |
245 | 1 0 | a Population-Based Cohort Study from a Prospective National Registry :b Better Long-Term Survival in Esophageal Cancer After Minimally Invasive Compared with Open Transthoracic Esophagectomy |
264 | c 2022-06-25 | |
264 | 1 | b Springer Nature,c 2022 |
338 | a print2 rdacarrier | |
520 | a Background Recent research indicates long-term survival benefits of minimally invasive esophagectomy (MIE) compared with open esophagectomy (OE) for patients with esophageal and gastroesophageal junction (GEJ) cancers, but there is a need for more population-based studies. Methods We conducted a prospective population-based nationwide cohort study including all patients in Sweden diagnosed with esophageal or junctional cancer who underwent a transthoracic esophagectomy with intrathoracic anastomosis. Data were collected from the Swedish National Register for Esophageal and Gastric Cancer in 2006-2019. Patients were grouped into OE and MIE including hybrid MIE (HMIE) and totally MIE (TMIE). Overall survival and short-term postoperative outcomes were compared using Cox regression and logistic regression models, respectively. All models were adjusted for age, sex, American Society of Anesthesiologists (ASA) score, clinical T and N stage, neoadjuvant therapy, year of surgery, and hospital volume. Results Among 1404 patients, 998 (71.1%) underwent OE and 406 (28.9%) underwent MIE. Compared with OE, overall survival was better following MIE (hazard ratio [HR] 0.72, 95% confidence interval [CI] 0.55-0.94), TMIE (HR 0.67, 95% CI 0.47-0.94), and possibly also after HMIE (HR 0.76, 95% CI 0.56-1.02). MIE was associated with shorter operation time, less intraoperative bleeding, higher number of resected lymph nodes, and shorter hospital stay compared with OE. MIE was also associated with fewer overall complications (odds ratio [OR] 0.70, 95% CI 0.47-1.03) as well as non-surgical complications (OR 0.64, 95% CI 0.40-1.00). Conclusions MIE seems to offer better survival and similar or improved short-term postoperative outcomes in esophageal and GEJ cancers compared with OE in this unselected population-based cohort. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng |
700 | 1 | a Ndegwa, Nelsonu Karolinska Inst, Div Surg, Dept Clin Sci Intervent & Technol CLINTEC, Stockholm, Sweden.;Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden.4 aut |
700 | 1 | a Lindblad, Matsu Karolinska Institutet,Karolinska Univ Hosp, Sweden; Karolinska Inst, Sweden4 aut |
700 | 1 | a Linder, Gustavu Uppsala universitet,Gastrointestinalkirurgi,Uppsala Univ, Sweden4 aut0 (Swepub:uu)gulin499 |
700 | 1 | a Hedberg, Jakob,d 1972-u Uppsala universitet,Gastrointestinalkirurgi,Uppsala Univ, Sweden4 aut0 (Swepub:uu)jakhe890 |
700 | 1 | a Edholm, Davidu Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US4 aut0 (Swepub:liu)daved38 |
700 | 1 | a Johansson, Janu Karolinska Institutet,Skane Univ Hosp, Sweden4 aut |
700 | 1 | a Lagergren, Jesperu Karolinska Univ Hosp, Karolinska Inst, Dept Mol Med & Surg, Upper Gastrointestinal Surg, Stockholm, Sweden.;Kings Coll London, Sch Canc & Pharmaceut Sci, London, England.4 aut |
700 | 1 | a Lundell, Larsu Karolinska Institutet,Karolinska Inst, Sweden; Odense Univ Hosp, Denmark4 aut |
700 | 1 | a Nilsson, Magnusu Karolinska Institutet,Karolinska Univ Hosp, Sweden; Karolinska Inst, Sweden4 aut |
700 | 1 | a Rouvelas, Ioannisu Karolinska Institutet,Karolinska Univ Hosp, Sweden; Karolinska Inst, Sweden4 aut |
710 | 2 | a Karolinska Univ Hosp, Dept Upper Abdominal Surg, Ctr Digest Dis, Stockholm, Sweden.;Japanese Fdn Canc Res, Canc Inst Hosp, Dept Surg Gastroenterol, Gastroenterol Ctr, Tokyo, Japan.b Karolinska Inst, Div Surg, Dept Clin Sci Intervent & Technol CLINTEC, Stockholm, Sweden.;Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden.4 org |
773 | 0 | t Annals of Surgical Oncologyd : Springer Natureg 29:9, s. 5609-5621q 29:9<5609-5621x 1068-9265x 1534-4681 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-485646 |
856 | 4 8 | u https://doi.org/10.1245/s10434-022-11922-5 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:149999543 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-186814 |
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