onr:"swepub:oai:DiVA.org:uu-486672"
Sökning: onr:"swepub:oai:DiVA.org:uu-486672" > Single cell metabol...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04269naa a2200469 4500 | |
| 001 | oai:DiVA.org:uu-486672 | |
| 003 | SwePub | |
| 008 | 221014s2022 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4866722 URI |
| 024 | 7 | a https://doi.org/10.1007/s11306-022-01934-32 DOI |
| 040 | a (SwePub)uu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a for2 swepub-publicationtype |
| 100 | 1 | a Ali, Ahmedu Leiden Univ, Leiden Acad Ctr Drug Res, Gorlaeus Bldg Einsteinweg 55, NL-2333 CC Leiden, Netherlands.4 aut |
| 245 | 1 0 | a Single cell metabolism :b current and future trends |
| 264 | c 2022-10-01 | |
| 264 | 1 | b Springer,c 2022 |
| 338 | a print2 rdacarrier | |
| 520 | a Single cell metabolomics is an emerging and rapidly developing field that complements developments in single cell analysis by genomics and proteomics. Major goals include mapping and quantifying the metabolome in sufficient detail to provide useful information about cellular function in highly heterogeneous systems such as tissue, ultimately with spatial resolution at the individual cell level. The chemical diversity and dynamic range of metabolites poses particular challenges for detection, identification and quantification. In this review we discuss both significant technical issues of measurement and interpretation, and progress toward addressing them, with recent examples from diverse biological systems. We provide a framework for further directions aimed at improving workflow and robustness so that such analyses may become commonly applied, especially in combination with metabolic imaging and single cell transcriptomics and proteomics. | |
| 650 | 7 | a NATURVETENSKAPx Biologix Biokemi och molekylärbiologi0 (SwePub)106022 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Biochemistry and Molecular Biology0 (SwePub)106022 hsv//eng |
| 653 | a Single cell metabolism | |
| 653 | a Spatial metabolomics | |
| 653 | a Metabolic imaging | |
| 700 | 1 | a Davidson, Shawnu Princeton Univ, Lewis Sigler Inst Integrat Genom, Princeton, NJ 08544 USA.4 aut |
| 700 | 1 | a Fraenkel, Ernestu MIT, Dept Biol Engn, 77 Massachusetts Ave, Cambridge, MA 02139 USA.;MIT, Computat & Syst Biol Program, 77 Massachusetts Ave, Cambridge, MA 02139 USA.4 aut |
| 700 | 1 | a Gilmore, Ianu Natl Phys Lab, Teddington TW11 0LW, Middx, England.4 aut |
| 700 | 1 | a Hankemeier, Thomasu Leiden Univ, Leiden Acad Ctr Drug Res, Room GW4 07,Gorlaeus Bldg,Einsteinweg 55, NL-2333 CC Leiden, Netherlands.4 aut |
| 700 | 1 | a Kirwan, Jennifer A.u Charite Univ Med Berlin, Berlin Inst Hlth, Metabol Platform, Translat Res Unit, Anna Louisa Karsch Str 2, D-10178 Berlin, Germany.4 aut |
| 700 | 1 | a Lane, Andrew N.u Univ Kentucky, Dept Toxicol & Canc Biol, 789 S Limestone St, Lexington, KY 40536 USA.;Univ Kentucky, Ctr Environm & Syst Biochem, 789 S Limestone St, Lexington, KY 40536 USA.4 aut |
| 700 | 1 | a Lanekoff, Ingela,c Assoc. Prof.d 1975-u Uppsala universitet,Analytisk kemi4 aut0 (Swepub:uu)ingla753 |
| 700 | 1 | a Larion, Mioarau NCI, Ctr Canc Res, Bldg 37,Room 1136A, Bethesda, MD 20892 USA.4 aut |
| 700 | 1 | a McCall, Laura-Isobelu Univ Oklahoma, Dept Chem & Biochem, Dept Microbiol & Plant Biol, Labs Mol Anthropol & Microbiome Res, 101 Stephenson Pkwy,room 3750, Norman, OK 73019 USA.4 aut |
| 700 | 1 | a Murphy, Michaelu MIT, Dept Biol Engn, Dept Elect Engn & Comp Sci, 77 Massachusetts Ave, Cambridge, MA 02139 USA.;MIT, Computat & Syst Biol Program, 77 Massachusetts Ave, Cambridge, MA 02139 USA.4 aut |
| 700 | 1 | a Sweedler, Jonathan V.u Univ Illinois, Dept Chem, 505 South Mathews Ave, Urbana, IL 61801 USA.;Univ Illinois, Beckman Inst, 505 South Mathews Ave, Urbana, IL 61801 USA.4 aut |
| 700 | 1 | a Zhu, Caigangu Univ Kentucky, Dept Biomed Engn, Lexington, KY 40536 USA.4 aut |
| 710 | 2 | a Leiden Univ, Leiden Acad Ctr Drug Res, Gorlaeus Bldg Einsteinweg 55, NL-2333 CC Leiden, Netherlands.b Princeton Univ, Lewis Sigler Inst Integrat Genom, Princeton, NJ 08544 USA.4 org |
| 773 | 0 | t Metabolomicsd : Springerg 18:10q 18:10x 1573-3882x 1573-3890 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-486672 |
| 856 | 4 8 | u https://doi.org/10.1007/s11306-022-01934-3 |
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