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An adaptive control...
An adaptive controller for propofol in anesthesia under synergistic remifentanil disturbances
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- Martins da Silva, Margarida (författare)
- Uppsala universitet,Avdelningen för systemteknik,Reglerteknik,Dep. Matematica Fac. Ciencias da Universidade do Porto, Porto, Portugal; Center for Research and Developments in Mathematics and Applications, Campus Universitario de Santiago, Aveiro, Portugal
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- Wigren, Torbjörn (författare)
- Uppsala universitet,Reglerteknik,Avdelningen för systemteknik
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- Mendonca, Teresa (författare)
- Dep. Matematica Fac. Ciencias da Universidade do Porto, Porto, Portugal; Center for Research and Developments in Mathematics and Applications, Campus Universitario de Santiago, Aveiro, Portuga
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(creator_code:org_t)
- Uppsala : Uppsala University, 2012
- Engelska 10 s.
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Serie: Technical report / Department of Information Technology, Uppsala University, 1404-3203 ; 2012-011
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Abstract
Ämnesord
Stäng
- An adaptive controller for propofol administration relying on a minimally parameterized SISO Wiener model for the depth of anesthesia is proposed. The exact linearization of this minimal Wiener structure using the continuous-time model parameters estimated online by an extended Kalman filter is a key point in the design. A linear quadratic Gaussian controller is developed for the exactly linearized system. The depth of anesthesia is considered to be measured by the bispectral index. Excellent results were obtained when the robustness of the proposed controller with respect to inter and intrapatient variability was assessed through simulations on a database of 500 patients. The closed-loop system showed good disturbance rejection properties when the synergistic effect of remifentanil in the depth of anesthesia was considered.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Elektroteknik och elektronik -- Reglerteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Electrical Engineering, Electronic Engineering, Information Engineering -- Control Engineering (hsv//eng)
Publikations- och innehållstyp
- vet (ämneskategori)
- rap (ämneskategori)