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Incidence, risk fac...
Incidence, risk factors and outcomes of acute kidney injury among COVID-19 patients : A systematic review of systematic reviews
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- Mallhi, Tauqeer Hussain (författare)
- Jouf Univ, Coll Pharm, Dept Clin Pharm, Sakaka, Saudi Arabia.
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- Khan, Yusra Habib (författare)
- Jouf Univ, Coll Pharm, Dept Clin Pharm, Sakaka, Saudi Arabia.;Jouf Univ, Hlth Sci Res Unit, Sakaka, Saudi Arabia.
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- Alzarea, Abdulaziz Ibrahim (författare)
- Jouf Univ, Coll Pharm, Dept Clin Pharm, Sakaka, Saudi Arabia.
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- Khan, Faiz Ullah (författare)
- Xi An Jiao Tong Univ, Sch Pharm, Dept Pharm Adm, Clin Pharm, Xian, Peoples R China.
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- Alotaibi, Nasser Hadal (författare)
- Jouf Univ, Coll Pharm, Dept Clin Pharm, Sakaka, Saudi Arabia.
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- Alanazi, Abdullah Salah (författare)
- Jouf Univ, Coll Pharm, Dept Clin Pharm, Sakaka, Saudi Arabia.;Jouf Univ, Hlth Sci Res Unit, Sakaka, Saudi Arabia.
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- Hammad Butt, Muhammad (författare)
- Uppsala universitet,Institutionen för läkemedelskemi
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- Alatawi, Ahmed D. (författare)
- Jouf Univ, Coll Pharm, Dept Clin Pharm, Sakaka, Saudi Arabia.
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- Salman, Muhammad (författare)
- Lahore Coll Women Univ, Inst Pharm, Fac Pharmaceut & Allied Hlth Sci, Lahore, Pakistan.
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- Alzarea, Sami I. (författare)
- Jouf Univ, Coll Pharm, Dept Pharmacol, Sakaka, Saudi Arabia.
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- Almalki, Ziyad Saeed (författare)
- Prince Sattam Bin Abdulaziz Univ, Coll Pharm, Dept Clin Pharm, Al Kharj, Saudi Arabia.
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- Alghazi, Mansoor A. (författare)
- King Abdul Aziz Med City, Dept Pharmaceut Care, Riyadh, Saudi Arabia.
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- Algarni, Majed Ahmed (författare)
- Taif Univ, Coll Pharm, Dept Clin Pharm, Taif, Saudi Arabia.
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Jouf Univ, Coll Pharm, Dept Clin Pharm, Sakaka, Saudi Arabia Jouf Univ, Coll Pharm, Dept Clin Pharm, Sakaka, Saudi Arabia.;Jouf Univ, Hlth Sci Res Unit, Sakaka, Saudi Arabia. (creator_code:org_t)
- 2022-11-04
- 2022
- Engelska.
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Ingår i: Frontiers in Medicine. - : Frontiers Media S.A.. - 2296-858X. ; 9
- Relaterad länk:
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https://doi.org/10.3...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Ämnesord
Stäng
- The COVID-19 associated acute kidney injury (CAKI) has emerged as a potential intricacy during the management of patients. Navigating the rapidly growing body of scientific literature on CAKI is challenging, and ongoing critical appraisal of this complication is essential. This study aimed to summarize and critically appraise the systematic reviews (SRs) on CAKI to inform the healthcare providers about its prevalence, risk factors and outcomes. All the SRs were searched in major databases (PubMed, EMBASE, Web of Science) from inception date to December 2021. This study followed SR of SRs methodology, all the records were screened, extracted and subjected to quality assessment by assessing the methodological quality of systematic reviews (AMSTAR-2). The extracted data were qualitatively synthesized and tabulated. This review protocol was registered in PROSPERO (CRD42022299444). Of 3,833 records identified; 42 SRs were included in this overview. The quality appraisal of the studies showed that 17 SRs were of low quality, while 8 moderate and 17 were of high-quality SRs. The incidence of CAKI ranged from 4.3% to 36.4% in overall COVID-19 patients, 36%-50% in kidney transplant recipients (KTRs), and up to 53% in severe or critical illness. Old age, male gender, cardiovascular disease, chronic kidney disease, diabetes mellitus and hypertension were frequently reported risk factors of CAKI. The need of renal replacement therapy (RRT) was up to 26.4% in overall COVID-19 patients, and 39% among those having CAKI. The occurrence of acute kidney injury (AKI) was found independent predictor of death, where mortality rate among CAKI patients ranged from 50% to 93%. This overview of SRs underscores that CAKI occurs frequently among COVID-19 patients and associated with high mortality, need of RRT and adverse outcomes. However, the confidence of these results is moderate to low which warrants the need of more SRs having established methodological standards.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- COVID-19
- SARS-CoV-2
- coronavirus
- acute kidney injury
- complications
- mortality
- risk factors
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Mallhi, Tauqeer ...
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Khan, Yusra Habi ...
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Alzarea, Abdulaz ...
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Khan, Faiz Ullah
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Alotaibi, Nasser ...
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Alanazi, Abdulla ...
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Hammad Butt, Muh ...
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Alatawi, Ahmed D ...
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Salman, Muhammad
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Alzarea, Sami I.
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Almalki, Ziyad S ...
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Alghazi, Mansoor ...
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Algarni, Majed A ...
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