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Peptide Conjugated ...
Peptide Conjugated Dihydroazulene/Vinylheptafulvene Photoswitches in Aqueous Environment
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- Corbet, Brian P. (författare)
- Univ Gottingen, Inst Organ & Biomol Chem, Dept Chem, Tammannstr 2, D-37077 Gottingen, Germany.;Univ Gottingen, Cluster Excellence Multiscale Bioimaging Mol Mach, D-37075 Gottingen, Germany.
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- Schlueter, J. Malte (författare)
- Univ Gottingen, Inst Organ & Biomol Chem, Dept Chem, Tammannstr 2, D-37077 Gottingen, Germany.
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- Cotroneo, Elena R. (författare)
- Univ Gottingen, Inst Organ & Biomol Chem, Dept Chem, Tammannstr 2, D-37077 Gottingen, Germany.
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- Crespi, Stefano (författare)
- Uppsala universitet,Syntetisk molekylär kemi
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- Simeth, Nadja A. (författare)
- Univ Gottingen, Inst Organ & Biomol Chem, Dept Chem, Tammannstr 2, D-37077 Gottingen, Germany.;Univ Gottingen, Cluster Excellence Multiscale Bioimaging Mol Mach, D-37075 Gottingen, Germany.
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Univ Gottingen, Inst Organ & Biomol Chem, Dept Chem, Tammannstr 2, D-37077 Gottingen, Germany;Univ Gottingen, Cluster Excellence Multiscale Bioimaging Mol Mach, D-37075 Gottingen, Germany. Univ Gottingen, Inst Organ & Biomol Chem, Dept Chem, Tammannstr 2, D-37077 Gottingen, Germany. (creator_code:org_t)
- 2022-11-24
- 2023
- Engelska.
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Ingår i: European Journal of Organic Chemistry. - : John Wiley & Sons. - 1434-193X .- 1099-0690. ; 26:1
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Light-responsive molecules have seen a major advance in modulating biological functions in recent years. Especially photoswitches are highly attractive building blocks due to the reversible nature of their light-mediated reactivity. They are frequently used to affect both the properties of small bioactive compounds and biomacromolecules if incorporated suitably. Despite their success in a plethora of applications, only a limited set of photochromic core structures is routinely employed and a large number of photochromic couples are under-investigated in biological context. Broadening the toolbox of photoswitches available to modulate biological activity would open new avenues and unlock the full potential of photoswitchable molecules for biological studies. In this work, we explore the photochemical and thermal properties of the dihydroazulene/vinylheptafulvene photochromic couple as peptide conjugates in aqueous environment.
Ämnesord
- NATURVETENSKAP -- Kemi -- Organisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Organic Chemistry (hsv//eng)
- NATURVETENSKAP -- Kemi -- Fysikalisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Physical Chemistry (hsv//eng)
Nyckelord
- Dihydroazulene
- Vinylheptafulvene
- Photochemistry
- Photopharmacology
- Photoswitches
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