Sökning: onr:"swepub:oai:DiVA.org:uu-498948" > Aggregation tests i...
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000 | 35327naa a2203349 4500 | |
001 | oai:DiVA.org:uu-498948 | |
003 | SwePub | |
008 | 230322s2023 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:152000895 | |
009 | oai:lup.lub.lu.se:03b290d6-d650-490a-9e52-2fcb867a25b3 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4989482 URI |
024 | 7 | a https://doi.org/10.1186/s13073-022-01152-52 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1520008952 URI |
024 | 7 | a https://lup.lub.lu.se/record/03b290d6-d650-490a-9e52-2fcb867a25b32 URI |
040 | a (SwePub)uud (SwePub)kid (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Mueller, Stefanie H.u UCL, Inst Hlth Informat, London, England.,University College London4 aut |
245 | 1 0 | a Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry |
264 | c 2023-01-26 | |
264 | 1 | b BioMed Central (BMC),c 2023 |
338 | a electronic2 rdacarrier | |
520 | a Background: Low-frequency variants play an important role in breast cancer (BC) susceptibility. Gene-based methods can increase power by combining multiple variants in the same gene and help identify target genes.Methods: We evaluated the potential of gene-based aggregation in the Breast Cancer Association Consortium cohorts including 83,471 cases and 59,199 controls. Low-frequency variants were aggregated for individual genes' coding and regulatory regions. Association results in European ancestry samples were compared to single-marker association results in the same cohort. Gene-based associations were also combined in meta-analysis across individuals with European, Asian, African, and Latin American and Hispanic ancestry.Results: In European ancestry samples, 14 genes were significantly associated (q < 0.05) with BC. Of those, two genes, FMNL3 (P = 6.11 x 10(-6)) and AC058822.1 (P = 1.47 x 10(-4)), represent new associations. High FMNL3 expression has previously been linked to poor prognosis in several other cancers. Meta-analysis of samples with diverse ancestry discovered further associations including established candidate genes ESR1 and CBLB. Furthermore, literature review and database query found further support for a biologically plausible link with cancer for genes CBLB, FMNL3, FGFR2, LSP1, MAP3K1, and SRGAP2C.Conclusions: Using extended gene-based aggregation tests including coding and regulatory variation, we report identification of plausible target genes for previously identified single-marker associations with BC as well as the discovery of novel genes implicated in BC development. Including multi ancestral cohorts in this study enabled the identification of otherwise missed disease associations as ESR1 (P = 1.31 x 10(-5)), demonstrating the importance of diversifying study cohorts. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
653 | a Breast cancer susceptibility | |
653 | a Diverse ancestry | |
653 | a Rare variants | |
653 | a Gene regulation | |
653 | a Genome-wide association study | |
653 | a Breast cancer susceptibility | |
653 | a Diverse ancestry | |
653 | a Gene regulation | |
653 | a Genome-wide association study | |
653 | a Rare variants | |
653 | a African | |
653 | a ancestry group | |
653 | a Article | |
653 | a Asian | |
653 | a boredom susceptibility | |
653 | a breast cancer | |
653 | a cancer prognosis | |
653 | a CBLB gene | |
653 | a cohort analysis | |
653 | a controlled study | |
653 | a ESR1 gene | |
653 | a European | |
653 | a FGFR2 gene | |
653 | a FMNL3 gene | |
653 | a gene base aggregation | |
653 | a gene expression level | |
653 | a gene structure | |
653 | a genetic association | |
653 | a genetic association study | |
653 | a genetic code | |
653 | a genetic variability | |
653 | a Hispanic | |
653 | a human | |
653 | a human cell | |
653 | a human tissue | |
653 | a LSP1 gene | |
653 | a major clinical study | |
653 | a MAP3K1 gene | |
653 | a meta analysis (topic) | |
653 | a South and Central America | |
653 | a SRGAP2C gene | |
653 | a statistical significance | |
653 | a tumor-related gene | |
653 | a Black person | |
653 | a breast tumor | |
653 | a female | |
653 | a genetic predisposition | |
653 | a genetic screening | |
653 | a genetics | |
653 | a genome-wide association study | |
653 | a meta analysis | |
653 | a procedures | |
653 | a single nucleotide polymorphism | |
653 | a FMNL3 protein, human | |
653 | a methenamine | |
653 | a Black People | |
653 | a Breast Neoplasms | |
653 | a Female | |
653 | a Formins | |
653 | a Genetic Predisposition to Disease | |
653 | a Genetic Testing | |
653 | a Genome-Wide Association Study | |
653 | a Humans | |
653 | a Polymorphism, Single Nucleotide | |
700 | 1 | a Lai, Alvina G.u UCL, Inst Hlth Informat, London, England.4 aut |
700 | 1 | a Valkovskaya, Mariau UCL, Div Psychiat, London, England.4 aut |
700 | 1 | a Michailidou, Kyriakiu Cyprus Inst Neurol & Genet, Biostat Unit, CY-2371 Nicosia, Cyprus.;Cyprus Inst Neurol & Genet, Cyprus Sch Mol Med, CY-2371 Nicosia, Cyprus.;Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Cambridge CB1 8RN, England.4 aut |
700 | 1 | a Bolla, Manjeet K.u Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Cambridge CB1 8RN, England.4 aut |
700 | 1 | a Wang, Qinu Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Cambridge CB1 8RN, England.4 aut |
700 | 1 | a Dennis, Joeu Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Cambridge CB1 8RN, England.4 aut |
700 | 1 | a Lush, Michaelu Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Cambridge CB1 8RN, England.4 aut |
700 | 1 | a Abu-Ful, Zomorudau Carmel Hosp, Clalit Natl Canc Control Ctr, IL-35254 Haifa, Israel.;Technion Fac Med, IL-35254 Haifa, Israel.4 aut |
700 | 1 | a Ahearn, Thomas U.u NCI, Div Canc Epidemiol & Genet, US Dept HHS, NIH, Bethesda, MD 20850 USA.4 aut |
700 | 1 | a Andrulis, Irene L.u Lunenfeld Tanenbaum Res Inst Mt Sinai Hosp, Fred A Litwin Ctr Canc Genet, Toronto, ON M5G 1X5, Canada.;Univ Toronto, Dept Mol Genet, Toronto, ON M5S 1A8, Canada.4 aut |
700 | 1 | a Anton-Culver, Hodau Univ Calif Irvine, Genet Epidemiol Res Inst, Dept Med, Irvine, CA 92617 USA.4 aut |
700 | 1 | a Antonenkova, Natalia N.u NN Alexandrov Res Inst Oncol & Med Radiol, Minsk 223040, BELARUS.4 aut |
700 | 1 | a Arndt, Volkeru German Canc Res Ctr, Div Clin Epidemiol & Aging Res, D-69120 Heidelberg, Germany.4 aut |
700 | 1 | a Aronson, Kristan J.u Queens Univ, Canc Res Inst, Dept Publ Hlth Sci, Kingston, ON K7L 3N6, Canada.4 aut |
700 | 1 | a Augustinsson, A.u Lund University,Lunds universitet,Karolinska Institutet,Vård i högteknologisk miljö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Cancerepidemiologi & strål,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Care in high technological environments,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Cancerepidemiology and radiation,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)med-aea |
700 | 1 | a Baert, Thaisu Univ Hosp Leuven, Leuven Multidisciplinary Breast Ctr, Leuven Canc Inst, Dept Oncol, B-3000 Louvain, Belgium.4 aut |
700 | 1 | a Freeman, Laura E. Beaneu NCI, Div Canc Epidemiol & Genet, US Dept HHS, NIH, Bethesda, MD 20850 USA.4 aut |
700 | 1 | a Beckmann, Matthias W.u Friedrich Alexander Univ Erlangen Nuremberg FAU, Univ Hosp Erlangen, Comprehens Canc Ctr Erlangen EMN, Dept Gynecol & Obstet, D-91054 Erlangen, Germany.4 aut |
700 | 1 | a Behrens, Sabineu German Canc Res Ctr, Div Canc Epidemiol, D-69120 Heidelberg, Germany.4 aut |
700 | 1 | a Benitez, Javieru Biomed Network Rare Dis CIBERER, Madrid 28029, Spain.;Spanish Natl Canc Res Ctr CNIO, Human Canc Genet Programme, Madrid 28029, Spain.4 aut |
700 | 1 | a Bermisheva, Marinau Russian Acad Sci, Inst Biochem & Genet, Ufa Fed Res Ctr, Ufa 450054, Russia.4 aut |
700 | 1 | a Blomqvist, Carlu Univ Helsinki, Helsinki Univ Hosp, Dept Oncol, Helsinki 00290, Finland.;Örebro Univ Hosp, Dept Oncol, S-70185 Örebro, Sweden.4 aut |
700 | 1 | a Bogdanova, Natalia, Vu NN Alexandrov Res Inst Oncol & Med Radiol, Minsk 223040, BELARUS.;Hannover Med Sch, Depart Ment Radiat Oncol, D-30625 Hannover, Germany.;Hannover Med Sch, Gynaecol Res Unit, D-30625 Hannover, Germany.4 aut |
700 | 1 | a Bojesen, Stig E.u Copenhagen Univ Hosp, Herlev & Gentofte Hosp, Copenhagen Gen Populat Study, DK-2730 Herlev, Denmark.;Copenhagen Univ Hosp, Herlev & Gentofte Hosp, Dept Clin Biochem, DK-2730 Herlev, Denmark.;Univ Copenhagen, Fac Hlth & Med Sci, DK-2200 Copenhagen, Denmark.4 aut |
700 | 1 | a Bonanni, Bernardou European Inst Oncol IRCCS, Div Canc Prevent & Genet, IEO, I-20141 Milan, Italy.,University College London4 aut |
700 | 1 | a Brenner, Hermannu German Canc Res Ctr, Div Clin Epidemiol & Aging Res, D-69120 Heidelberg, Germany.;German Canc Res Ctr, Natl Ctr Tumor Dis NCT, Div Prevent Oncol, D-69120 Heidelberg, Germany.;German Canc Res Ctr, German Canc Consortium DKTK, D-69120 Heidelberg, Germany.4 aut |
700 | 1 | a Brucker, Sara Y.u Univ Tubingen, Dept Gynecol & Obstet, D-72076 Tubingen, Germany.4 aut |
700 | 1 | a Buys, Saundra S.u Huntsman Canc Inst, Dept Med, Salt Lake City, UT 84112 USA.4 aut |
700 | 1 | a Castelao, Jose E.u Inst Invest Sanitaria Galicia Sur IISGS, Oncol & Genet Unit, Xerencia Xest Integrada Vigo SERGAS, Vigo 36312, Spain.4 aut |
700 | 1 | a Chan, Tsun L.u Hong Kong Hereditary Breast Canc Family Registry, Hong Kong, Peoples R China.;Hong Kong Sanat & Hosp, Dept Mol Pathol, Hong Kong, Peoples R China.4 aut |
700 | 1 | a Chang-Claude, Jennyu German Canc Res Ctr, Div Canc Epidemiol, D-69120 Heidelberg, Germany.;Univ Canc Ctr Hamburg UCCH, Univ Med Ctr Hamburg Eppendorf, Canc Epidemiol Grp, D-20246 Hamburg, Germany.4 aut |
700 | 1 | a Chanock, Stephen J.u NCI, Div Canc Epidemiol & Genet, US Dept HHS, NIH, Bethesda, MD 20850 USA.4 aut |
700 | 1 | a Choi, Ji-Yeobu Seoul Natl Univ, Dept Biomed Sci, Grad Sch, Seoul 03080, South Korea.;Seoul Natl Univ, Canc Res Inst, Seoul 03080, South Korea.;Seoul Natl Univ, Inst Hlth Policy & Management, Med Res Ctr, Seoul 03080, South Korea.4 aut |
700 | 1 | a Chung, Wendy K.u Karolinska Institutet4 aut |
700 | 1 | a Colonna, Sarah, Vu Huntsman Canc Inst, Dept Med, Salt Lake City, UT 84112 USA.4 aut |
700 | 1 | a Cornelissen, Stenu Netherlands Canc Inst, Div Mol Pathol, Antoni Van Leeuwenhoek Hosp, NL-1066 CX Amsterdam, Netherlands.4 aut |
700 | 1 | a Couch, Fergus J.u Mayo Clin, Dept Lab Med & Pathol, Rochester, MN 55905 USA.4 aut |
700 | 1 | a Czene, Kamilau Karolinska Institutet4 aut |
700 | 1 | a Daly, Mary B.u Fox Chase Canc Ctr, Dept Clin Genet, Philadelphia, PA 19111 USA.4 aut |
700 | 1 | a Devilee, Peteru Leiden Univ Med Ctr, Dept Pathol, NL-2333 ZA Leiden, Netherlands.;Leiden Univ Med Ctr, Dept Human Genet, NL-2333 ZA Leiden, Netherlands.4 aut |
700 | 1 | a Dork, Thilou Hannover Med Sch, Gynaecol Res Unit, D-30625 Hannover, Germany.4 aut |
700 | 1 | a Dossus, Laureu Int Agcy Res Canc IARC WHO, Nutr & Metab Sect, F-69372 Lyon, France.4 aut |
700 | 1 | a Dwek, Miriamu Univ Westminster, Sch Life Sci, London W1W 6UW, England.4 aut |
700 | 1 | a Eccles, Diana M.u Univ Southampton, Fac Med, Southampton SO17 1BJ, Hants, England.4 aut |
700 | 1 | a Ekici, Arif B.u Friedrich Alexander Univ Erlangen Nuremberg FAU, Univ Hosp Erlangen, Comprehens Canc Ctr Erlangen EMN, Inst Human Genet, D-91054 Erlangen, Germany.4 aut |
700 | 1 | a Eliassen, A. Heatheru Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Channing Div Network Med, Boston, MA 02115 USA.;Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.;Harvard TH Chan Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA.4 aut |
700 | 1 | a Engel, Christophu Univ Leipzig, Inst Med Informat Stat & Epidemiol, D-04107 Leipzig, Germany.;Univ Leipzig, LIFE Leipzig Res Ctr Civilizat Dis, D-04103 Leipzig, Germany.4 aut |
700 | 1 | a Evans, D. Garethu Univ Manchester, Manchester Acad Hlth Sci Ctr, Fac Biol, Sch Biol Sci, Manchester, Lancs, England.;Manchester Univ NHS Fdn Trust, Manchester Acad Hlth Sci Ctr, Manchester Ctr Genom Med, North West Genom Lab Hub,St Marys Hosp, Manchester, Lancs, England.4 aut |
700 | 1 | a Fasching, Peter A.u Friedrich Alexander Univ Erlangen Nuremberg FAU, Univ Hosp Erlangen, Comprehens Canc Ctr Erlangen EMN, Dept Gynecol & Obstet, D-91054 Erlangen, Germany.;Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Div Hematol & Oncol, Los Angeles, CA 90095 USA.4 aut |
700 | 1 | a Fletcher, Oliviau Breast Canc Now Toby Robins Res Ctr, Inst Canc Res, London SW7 3RP, England.4 aut |
700 | 1 | a Flyger, Henriku Copenhagen Univ Hosp, Herlev & Gentofte Hosp, Dept Breast Surg, DK-2730 Herlev, Denmark.4 aut |
700 | 1 | a Gago-Dominguez, Manuelau Complejo Hosp Univ Santiago, Inst Invest Sanitaria Santiago Compostela IDIS, SERGAS, Fdn Poebl Galega Med Xenom, Santiago De Compostela 15706, Spain.;Univ Calif San Diego, Moores Canc Ctr, La Jolla, CA 92037 USA.4 aut |
700 | 1 | a Gao, Yu-Tangu Shanghai Canc Inst, Dept Epidemiol, Shanghai 20032, Peoples R China.4 aut |
700 | 1 | a Garcia-Closas, Montserratu NCI, Div Canc Epidemiol & Genet, US Dept HHS, NIH, Bethesda, MD 20850 USA.4 aut |
700 | 1 | a Garcia-Saenz, Jose A.u Hosp Clin San Carlos, Ctr Invest Biomed Red Canc CIBERONC, Inst Invest Sanitaria San Carlos IdISSC, Med Oncol Dept, Madrid 28040, Spain.4 aut |
700 | 1 | a Genkinger, Jeanineu Columbia Univ, Mailman Sch Publ Hlth, Dept Epidemiol, New York, NY 10032 USA.4 aut |
700 | 1 | a Gentry-Maharaj, Aleksandrau UCL, Inst Clin Trials & Methodol, London WC1V 6LJ, England.4 aut |
700 | 1 | a Grassmann, Felixu Karolinska Institutet4 aut |
700 | 1 | a Guenel, Pascalu Univ Paris Saclay, Ctr Res Epidemiol & Populat Hlth CESP, INSERM, Team Exposome & Hered, F-94805 Villejuif, France.4 aut |
700 | 1 | a Gundert, Melanieu German Canc Res Ctr, Mol Epidemiol Grp, C08069120, Heidelberg, Germany.;Heidelberg Univ, Univ Womens Clin Heidelberg, Mol Biol Breast Canc, D-69120 Heidelberg, Germany.;Helmholtz Zentrum Munchen, Inst Diabet Res, German Res Ctr Environm Hlth, D-85764 Neuherberg, Germany.4 aut |
700 | 1 | a Haeberle, Lotharu Friedrich Alexander Univ Erlangen Nuremberg FAU, Univ Hosp Erlangen, Comprehens Canc Ctr Erlangen EMN, Dept Gynecol & Obstet, D-91054 Erlangen, Germany.4 aut |
700 | 1 | a Hahnen, Ericu Univ Cologne, Univ Hosp Cologne, Fac Med, Ctr Familial Breast & Ovarian Canc, D-50937 Cologne, Germany.;Univ Cologne, Univ Hosp Cologne, Fac Med, Ctr Integrated Oncol CIO, D-50937 Cologne, Germany.4 aut |
700 | 1 | a Haiman, Christopher A.u Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Los Angeles, CA 90033 USA.4 aut |
700 | 1 | a Hakansson, Niclasu Karolinska Institutet4 aut |
700 | 1 | a Hall, Peru Karolinska Institutet4 aut |
700 | 1 | a Harkness, Elaine F.u Univ Manchester, Manchester Acad Hlth Sci Ctr, Fac Biol, Div Informat, Manchester, Lancs, England.;Manchester Univ NHS Fdn Trust, Wythenshawe Hosp, Nightingale & Genesis Prevent Ctr, Manchester, Lancs, England.;Manchester Univ NHS Fdn Trust, Manchester Acad Hlth Sci Ctr, NIHR Manchester Biomed Res Unit, Manchester, Lancs, England.4 aut |
700 | 1 | a Harrington, Patricia A.u Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Oncol, Cambridge, England.4 aut |
700 | 1 | a Hartikainen, Jaana M.u Univ Eastern Finland, Translat Canc Res Area, Kuopio 70210, Finland.;Univ Eastern Finland, Inst Clin Med Pathol & Forens Med, Kuopio 70210, Finland.4 aut |
700 | 1 | a Hartman, Mikaelu Natl Univ Singapore, Natl Univ Hlth Syst, Saw Swee Hock Sch Publ Hlth, Singapore 119077, Singapore.;Natl Univ Hlth Syst, Dept Surg, Singapore 119228, Singapore.4 aut |
700 | 1 | a Hein, Alexanderu Friedrich Alexander Univ Erlangen Nuremberg FAU, Univ Hosp Erlangen, Comprehens Canc Ctr Erlangen EMN, Dept Gynecol & Obstet, D-91054 Erlangen, Germany.4 aut |
700 | 1 | a Ho, Weang-Keeu Univ Nottingham, Dept Math Sci, Fac Sci & Engn, Malaysia Campus, Semenyih 43500, Selangor, Malaysia.;Canc Res Malaysia, Breast Canc Res Programme, Subang Jaya 47500, Selangor, Malaysia.4 aut |
700 | 1 | a Hooning, Maartje J.u Erasmus MC Canc Inst, Dept Med Oncol, NL-3015 GD Rotterdam, Netherlands.4 aut |
700 | 1 | a Hoppe, Reineru Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-70376 Stuttgart, Germany.;Univ Tubingen, D-72074 Tubingen, Germany.4 aut |
700 | 1 | a Hopper, John L.u Univ Melbourne, Ctr Epidemiol & Biostat, Melbourne Sch Populat & Global Hlth, Melbourne, Vic 3010, Australia.4 aut |
700 | 1 | a Houlston, Richard S.u Inst Canc Res, Div Genet & Epidemiol Ogy, London SM2 5NG, England.4 aut |
700 | 1 | a Howell, Anthonyu Univ Manchester, Div Canc Sci, Manchester M13 9PL, Lancs, England.4 aut |
700 | 1 | a Hunter, David J.u Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.;Univ Oxford, Nuffield Dept Populat Hlth, Oxford OX3 7LF, England.4 aut |
700 | 1 | a Huo, Dezhengu Univ Chicago, Ctr Clin Canc Genet, Chicago, IL 60637 USA.4 aut |
700 | 1 | a Investigators, Abctbu Univ Sydney, Westmead Inst Med Res, Australian Breast Canc Tissue Bank, Sydney, NSW 2145, Australia.4 aut |
700 | 1 | a Ito, Hidemiu Aichi Canc Ctr Res Inst, Div Canc Informat & Control, Nagoya, Aichi 4648681, Japan.;Nagoya Univ, Div Canc Epidemiol, Grad Sch Med, Nagoya, Aichi 4668550, Japan.4 aut |
700 | 1 | a Iwasaki, Motokiu Natl Canc Ctr Inst Canc Control, Ctr Publ Hlth Sci, Div Epidemiol, Tokyo 1040045, Japan.4 aut |
700 | 1 | a Jakubowska, Annau Pomeranian Med Univ, Dept Genet & Pathol, PL-71252 Szczecin, Poland.;Pomeranian Med Univ, Independent Lab Mol Biol & Genet Diagnost, PL-71252 Szczecin, Poland.4 aut |
700 | 1 | a Janni, Wolfgangu Univ Hosp Ulm, Dept Gynaecol & Obstet, D-89075 Ulm, Germany.4 aut |
700 | 1 | a John, Esther M.u Stanford Univ, Sch Med, Dept Epidemiol & Populat Hlth, Stanford, CA 94305 USA.;Stanford Univ, Sch Med, Stanford Canc Inst, Dept Med, Stanford, CA 94304 USA.4 aut |
700 | 1 | a Jones, Michael E.u Inst Canc Res, Div Genet & Epidemiol Ogy, London SM2 5NG, England.4 aut |
700 | 1 | a Jung, Audreyu German Canc Res Ctr, Div Canc Epidemiol, D-69120 Heidelberg, Germany.4 aut |
700 | 1 | a Kaaks, Rudolfu German Canc Res Ctr, Div Canc Epidemiol, D-69120 Heidelberg, Germany.4 aut |
700 | 1 | a Kang, Daeheeu Seoul Natl Univ, Canc Res Inst, Seoul 03080, South Korea.;Seoul Natl Univ, Coll Med, Dept Prevent Med, Seoul 03080, South Korea.4 aut |
700 | 1 | a Khusnutdinova, Elza K.u Russian Acad Sci, Inst Biochem & Genet, Ufa Fed Res Ctr, Ufa 450054, Russia.;Bashkir State Univ, Dept Genet & Fundamental Med, Ufa 450000, Russia.4 aut |
700 | 1 | a Kim, Sung-Wonu Daerim St Marys Hosp, Dept Surg, Seoul 07442, South Korea.4 aut |
700 | 1 | a Kitahara, Cari M.u NCI, Radiat Epidemiol Branch, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.4 aut |
700 | 1 | a Koutros, Stellau NCI, Div Canc Epidemiol & Genet, US Dept HHS, NIH, Bethesda, MD 20850 USA.4 aut |
700 | 1 | a Kraft, Peteru Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.;Harvard TH Chan Sch Publ Hlth, Program Genet Epidemiol & Stat Genet, Boston, MA 02115 USA.4 aut |
700 | 1 | a Kristensen, Vessela N.u Univ Oslo, Fac Med, Inst Clin Med, N-0450 Oslo, Norway. Vestre Viken Hosp, Dept Res, N-3019 Drammen, Norway. Oslo Univ Hosp Ullev, Dept Canc, Div Surg, Sect Breast & Endocrine Surg, N-0450 Oslo, Norway. Oslo Univ Hosp, Dept Radiol & Nucl Med, N-0379 Oslo, Norway. Akershus Univ Hosp, Dept Pathol, N-1478 Lorenskog, Norway. Oslo Univ Hosp, Inst Canc Res, Dept Tumor Biol, N-0379 Oslo, Norway. Oslo Univ Hosp, Dept Oncol, Div Surg Canc & Transplantat Med, Radiumhosp, N-0379 Oslo, Norway. Oslo Univ Hosp, Natl Advisory Unit Late Effects Canc Treatment, N-0379 Oslo, Norway. Akershus Univ Hosp, Dept Oncol, N-1478 Lorenskog, Norway. Oslo Univ Hosp, Oslo Breast Canc Res Consortium, N-0379 Oslo, Norway.;Oslo Univ Hosp, Dept Med Genet, N-0379 Oslo, Norway.;Univ Oslo, N-0379 Oslo, Norway.4 aut |
700 | 1 | a Kubelka-Sabit, Katerinau Clin Hosp Acibadem Sistina, Dept Histopathol & Cytol, Skopje 1000, North Macedonia.4 aut |
700 | 1 | a Kurian, Allison W.u Stanford Univ, Sch Med, Dept Epidemiol & Populat Hlth, Stanford, CA 94305 USA.;Stanford Univ, Sch Med, Stanford Canc Inst, Dept Med, Stanford, CA 94304 USA.4 aut |
700 | 1 | a Kwong, Avau Hong Kong Hereditary Breast Canc Family Registry, Hong Kong, Peoples R China.;Univ Hong Kong, Dept Surg, Hong Kong, Peoples R China.;Hong Kong Sanat & Hosp, Dept Surg, Hong Kong, Peoples R China.;Hong Kong Sanat & Hosp, Canc Genet Ctr, Hong Kong, Peoples R China.4 aut |
700 | 1 | a Lacey, James, Vu City Hope Natl Med Ctr, Depart Ment Computat & Quantitat Med, Duarte, CA 91010 USA.;City Hope Natl Med Ctr, City Hope Comprehens Canc Ctr, Duarte, CA 91010 USA.4 aut |
700 | 1 | a Lambrechts, Dietheru VIB Ctr Canc Biol, B-3001 Louvain, Belgium.;Univ Leuven, Dept Human Genet, Lab Translat Genet, B-3000 Louvain, Belgium.4 aut |
700 | 1 | a Le Marchand, Loicu Univ Hawaii Canc Ctr, Epidemiol Program, Honolulu, HI 96813 USA.4 aut |
700 | 1 | a Li, Jingmeiu Genome Inst Singapore, Human Genet Div, Singapore 138672, Singapore.4 aut |
700 | 1 | a Linet, Marthau NCI, Radiat Epidemiol Branch, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.4 aut |
700 | 1 | a Lo, Wing-Yeeu Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-70376 Stuttgart, Germany.;Univ Tubingen, D-72074 Tubingen, Germany.4 aut |
700 | 1 | a Long, Jirongu Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Vanderbilt Ingram Canc Ctr, Dept Med,Sch Med, Nashville, TN 37232 USA.4 aut |
700 | 1 | a Lophatananon, Artitayau Univ Manchester, Fac Biol, Sch Hlth Sci, Div Populat Hlth Hlth Serv Res & Primary Care, Manchester M13 9PL, Lancs, England.4 aut |
700 | 1 | a Mannermaa, Artou Univ Eastern Finland, Translat Canc Res Area, Kuopio 70210, Finland.;Univ Eastern Finland, Inst Clin Med Pathol & Forens Med, Kuopio 70210, Finland.;Kuopio Univ Hosp, Biobank Eastern Finland, Kuopio, Finland.4 aut |
700 | 1 | a Manoochehri, Mehdiu German Canc Res Ctr, Mol Genet Breast Canc, D-69120 Heidelberg, Germany.4 aut |
700 | 1 | a Margolin, Sarau Karolinska Institutet4 aut |
700 | 1 | a Matsuo, Keitarou Nagoya Univ, Div Canc Epidemiol, Grad Sch Med, Nagoya, Aichi 4668550, Japan.;Aichi Canc Ctr Res Inst, Div Canc Epidemiol & Prevent, Nagoya, Aichi 4648681, Japan.4 aut |
700 | 1 | a Mavroudis, Dimitriosu Univ Hosp Heraklion, Dept Med Oncol, Iraklion 71110, Greece.4 aut |
700 | 1 | a Menon, Ushau UCL, Inst Clin Trials & Methodol, London WC1V 6LJ, England.4 aut |
700 | 1 | a Muir, Kennethu Univ Manchester, Fac Biol, Sch Hlth Sci, Div Populat Hlth Hlth Serv Res & Primary Care, Manchester M13 9PL, Lancs, England.4 aut |
700 | 1 | a Murphy, Rachel A.u Univ British Columbia, Sch Populat & Publ Hlth, Vancouver, BC V6T 1Z4, Canada.;BC Canc, Canc Control Res, Vancouver, BC V5Z 1L3, Canada.4 aut |
700 | 1 | a Nevanlinna, Heliu Univ Helsinki, Helsinki Univ Hosp, Dept Obstet & Gynecol, Helsinki 00290, Finland.4 aut |
700 | 1 | a Newman, William G.u Univ Manchester, Manchester Acad Hlth Sci Ctr, Fac Biol, Sch Biol Sci, Manchester, Lancs, England.;Manchester Univ NHS Fdn Trust, Manchester Acad Hlth Sci Ctr, Manchester Ctr Genom Med, North West Genom Lab Hub,St Marys Hosp, Manchester, Lancs, England.4 aut |
700 | 1 | a Niederacher, Dieteru Heinrich Heine Univ Dusseldorf, Univ Hosp Dusseldorf, Dept Gynecol & Obstet, D-40225 Dusseldorf, Germany.4 aut |
700 | 1 | a O'Brien, Katie M.u NIEHS, Epidemiol Branch, NIH, Res Triangle Pk, NC 27709 USA.4 aut |
700 | 1 | a Obi, Nadiau Univ Med Ctr Hamburg Eppendorf, Inst Med Biometry & Epidemiol, D-20246 Hamburg, Germany.4 aut |
700 | 1 | a Offit, Kennethu Mem Sloan Kettering Canc Ctr, Dept Canc Biol & Genet, Clin Genet Res Lab, New York, NY 10065 USA.;Mem Sloan Kettering Canc Ctr, Dept Med, Clin Genet Serv, New York, NY 10065 USA.4 aut |
700 | 1 | a Olopade, Olufunmilayo, Iu Univ Chicago, Ctr Clin Canc Genet, Chicago, IL 60637 USA.4 aut |
700 | 1 | a Olshan, Andrew F.u Univ North Carolina Chapel Hill, Dept Epidemiol, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA.;Univ North Carolina Chapel Hill, UNC Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA.4 aut |
700 | 1 | a Olsson, H.u Lund University,Lunds universitet,Lunds Melanomstudiegrupp,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Biomarkörer och Epi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lund Melanoma Study Group,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Biomarkers and epidemiology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)onk-hol |
700 | 1 | a Park, Sue K.u Seoul Natl Univ, Canc Res Inst, Seoul 03080, South Korea.;Seoul Natl Univ, Coll Med, Dept Prevent Med, Seoul 03080, South Korea.;Seoul Natl Univ, Coll Med, Integrated Major Innovat Med Sci, Seoul 03080, South Korea.4 aut |
700 | 1 | a Patel, Alpa, Vu Amer Canc Soc, Dept Populat Sci, Atlanta, GA 30303 USA.4 aut |
700 | 1 | a Patel, Achalu Univ North Carolina Chapel Hill, Dept Epidemiol, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA.;Univ North Carolina Chapel Hill, UNC Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA.4 aut |
700 | 1 | a Perou, Charles M.u Univ North Carolina Chapel Hill, Dept Genet, Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA.4 aut |
700 | 1 | a Peto, Julianu London Sch Hyg & Trop Med, Dept Noncommunicable Dis Epidemiol, London WC1E 7HT, England.4 aut |
700 | 1 | a Pharoah, Paul D. P.u Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Cambridge CB1 8RN, England.;Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Oncol, Cambridge, England.4 aut |
700 | 1 | a Plaseska-Karanfilska, Dijanau MASA, Res Ctr Genet Engn & Biotechnol Georgi D Efremov, Skopje 1000, North Macedonia.4 aut |
700 | 1 | a Presneau, Nadegeu Univ Westminster, Sch Life Sci, London W1W 6UW, England.4 aut |
700 | 1 | a Rack, Brigitteu Univ Hosp Ulm, Dept Gynaecol & Obstet, D-89075 Ulm, Germany.4 aut |
700 | 1 | a Radice, Paolou Fdn IRCCS Ist Nazl Tumori INT, Dept Res, Unit Mol Bases Genet Risk & Genet Testing, I-20133 Milan, Italy.4 aut |
700 | 1 | a Ramachandran, Dhanyau Hannover Med Sch, Gynaecol Res Unit, D-30625 Hannover, Germany.4 aut |
700 | 1 | a Rashid, Muhammad U.u German Canc Res Ctr, Mol Genet Breast Canc, D-69120 Heidelberg, Germany.;Shaukat Khanum Mem Canc Hosp & Res Ctr SKMCH & RC, Dept Basic Sci, Lahore 54000, Pakistan.4 aut |
700 | 1 | a Rennert, Gadu Carmel Hosp, Clalit Natl Canc Control Ctr, IL-35254 Haifa, Israel.;Technion Fac Med, IL-35254 Haifa, Israel.4 aut |
700 | 1 | a Romero, Atochau Hosp Univ Puerta de Hierro, Med Oncol Dept, Madrid 28222, Spain.4 aut |
700 | 1 | a Ruddy, Kathryn J.u Mayo Clin, Dept Oncol, Rochester, MN 55905 USA.4 aut |
700 | 1 | a Ruebner, Matthiasu Friedrich Alexander Univ Erlangen Nuremberg FAU, Univ Hosp Erlangen, Comprehens Canc Ctr Erlangen EMN, Dept Gynecol & Obstet, D-91054 Erlangen, Germany.4 aut |
700 | 1 | a Saloustros, Emmanouilu Univ Hosp Larissa, Dept Oncol, Larisa 41110, Greece.4 aut |
700 | 1 | a Sandler, Dale P.u NIEHS, Epidemiol Branch, NIH, Res Triangle Pk, NC 27709 USA.4 aut |
700 | 1 | a Sawyer, Elinor J.u Kings Coll London, Comprehens Canc Ctr, Sch Canc & Pharmaceut Sci, Guys Campus, London, England.4 aut |
700 | 1 | a Schmidt, Marjanka K.u Netherlands Canc Inst, Div Mol Pathol, Antoni Van Leeuwenhoek Hosp, NL-1066 CX Amsterdam, Netherlands.;Antoni Van Leeuwenhoek Hosp, Div Psychosocial Res & Epidemiol, Netherlands Canc Inst, NL-1066 CX Amsterdam, Netherlands.4 aut |
700 | 1 | a Schmutzler, Rita K.u Univ Cologne, Univ Hosp Cologne, Fac Med, Ctr Familial Breast & Ovarian Canc, D-50937 Cologne, Germany.;Univ Cologne, Univ Hosp Cologne, Fac Med, Ctr Integrated Oncol CIO, D-50937 Cologne, Germany.;Univ Cologne, Fac Med, Ctr Mol Med Cologne CMMC, D-50931 Cologne, Germany.;Univ Cologne, Univ Hosp Cologne, D-50931 Cologne, Germany.4 aut |
700 | 1 | a Schneider, Michael O.u Friedrich Alexander Univ Erlangen Nuremberg FAU, Univ Hosp Erlangen, Comprehens Canc Ctr Erlangen EMN, Dept Gynecol & Obstet, D-91054 Erlangen, Germany.4 aut |
700 | 1 | a Scott, Christopheru Mayo Clin, Dept Hlth Sci Res, Rochester, MN 55905 USA.4 aut |
700 | 1 | a Shah, Mitulu Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Oncol, Cambridge, England.4 aut |
700 | 1 | a Sharma, Priyankau Univ Kansas Med Ctr, Dept Internal Med, Div Med Oncol, Westwood, KS 66205 USA.4 aut |
700 | 1 | a Shen, Chen-Yangu Acad Sinica, Inst Biomed Sci, Taipei 115, Taiwan.;China Med Univ, Sch Publ Hlth, Taichung, Taiwan.4 aut |
700 | 1 | a Shu, Xiao-Ouu Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Vanderbilt Ingram Canc Ctr, Dept Med,Sch Med, Nashville, TN 37232 USA.4 aut |
700 | 1 | a Simard, Jacquesu Ctr Hosp Univ Quebec Univ Laval Res Ctr, Genom Ctr, Quebec City, PQ G1V 4G2, Canada.4 aut |
700 | 1 | a Surowy, Haraldu German Canc Res Ctr, Mol Epidemiol Grp, C08069120, Heidelberg, Germany.;Heidelberg Univ, Univ Womens Clin Heidelberg, Mol Biol Breast Canc, D-69120 Heidelberg, Germany.4 aut |
700 | 1 | a Tamimi, Rulla M.u Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.;Weill Cornell Med, Dept Populat Hlth Sci, New York, NY 10065 USA.4 aut |
700 | 1 | a Tapper, William J.u Univ Southampton, Fac Med, Southampton SO17 1BJ, Hants, England.4 aut |
700 | 1 | a Taylor, Jack A.u NIEHS, Epidemiol Branch, NIH, Res Triangle Pk, NC 27709 USA.;NIEHS, Epigenet & Stem Cell Biol Lab, NIH, Res Triangle Pk, NC 27709 USA.4 aut |
700 | 1 | a Teo, Soo Hwangu Canc Res Malaysia, Breast Canc Res Programme, Subang Jaya 47500, Selangor, Malaysia.;Univ Malaya, Fac Med, Dept Surg, Kuala Lumpur 50603, Malaysia.4 aut |
700 | 1 | a Teras, Lauren R.u Amer Canc Soc, Dept Populat Sci, Atlanta, GA 30303 USA.4 aut |
700 | 1 | a Toland, Amanda E.u Ohio State Univ, Dept Canc Biol & Genet, Columbus, OH 43210 USA.4 aut |
700 | 1 | a Tollenaar, Rob A. E. M.u Leiden Univ Med Ctr, Dept Surg, NL-2333 ZA Leiden, Netherlands.4 aut |
700 | 1 | a Torres, Dianau German Canc Res Ctr, Mol Genet Breast Canc, D-69120 Heidelberg, Germany.;Pontificia Univ Javeriana, Inst Human Genet, Bogota 110231, Colombia.4 aut |
700 | 1 | a Torres-Mejia, Gabrielau Ctr Populat Hlth Res, Natl Inst Publ Hlth, Cuernavaca 62100, Morelos, Mexico.4 aut |
700 | 1 | a Troester, Melissa A.u Univ North Carolina Chapel Hill, Dept Epidemiol, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA.;Univ North Carolina Chapel Hill, UNC Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA.4 aut |
700 | 1 | a Truong, Thereseu Univ Paris Saclay, Ctr Res Epidemiol & Populat Hlth CESP, INSERM, Team Exposome & Hered, F-94805 Villejuif, France.4 aut |
700 | 1 | a Vachon, Celine M.u Mayo Clin, Div Epidemiol, Dept Quantitat Hlth Sci, Rochester, MN 55905 USA.4 aut |
700 | 1 | a Vijai, Josephu Mem Sloan Kettering Canc Ctr, Dept Canc Biol & Genet, Clin Genet Res Lab, New York, NY 10065 USA.;Mem Sloan Kettering Canc Ctr, Dept Med, Clin Genet Serv, New York, NY 10065 USA.4 aut |
700 | 1 | a Weinberg, Clarice R.u NIEHS, Biostat & Computat Biol Branch, NIH, Res Triangle Pk, NC 27709 USA.4 aut |
700 | 1 | a Wendt, Camillau Karolinska Inst, Dept Clin Sci & Educ, Sodersjukhuset, S-11883 Stockholm, Sweden.4 aut |
700 | 1 | a Winqvist, Robertu Univ Oulu, Bioctr Oulu, Canc & Translat Med Res Unit, Lab Canc Genet & Tumor Biol, Oulu 90570, Finland.;Northern Finland Lab Ctr Oulu, Lab Canc Genet & Tumor Biol, Oulu 90570, Finland.4 aut |
700 | 1 | a Wolk, Alicjau Uppsala universitet,Institutionen för kirurgiska vetenskaper,Karolinska Inst, Inst Environm Med, S-17177 Stockholm, Sweden.4 aut0 (Swepub:uu)alwol516 |
700 | 1 | a Wu, Anna H.u Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Los Angeles, CA 90033 USA.4 aut |
700 | 1 | a Yamaji, Taikiu Natl Canc Ctr Inst Canc Control, Ctr Publ Hlth Sci, Div Epidemiol, Tokyo 1040045, Japan.4 aut |
700 | 1 | a Yang, Xiaohong R.u NCI, Div Canc Epidemiol & Genet, US Dept HHS, NIH, Bethesda, MD 20850 USA.4 aut |
700 | 1 | a Yu, Jyh-Cherngu Triserv Gen Hosp, Natl Def Med Ctr, Dept Surg, Taipei 114, Taiwan.4 aut |
700 | 1 | a Zheng, Weiu Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Vanderbilt Ingram Canc Ctr, Dept Med,Sch Med, Nashville, TN 37232 USA.4 aut |
700 | 1 | a Ziogas, Argyriosu Univ Calif Irvine, Genet Epidemiol Res Inst, Dept Med, Irvine, CA 92617 USA.4 aut |
700 | 1 | a Ziv, Eladu Univ Calif San Francisco, Diller Family Comprehens Canc Ctr, Inst Human Genet, Dept Med, San Francisco, CA 94115 USA.4 aut |
700 | 1 | a Dunning, Alison M.u Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Oncol, Cambridge, England.4 aut |
700 | 1 | a Easton, Douglas F.u Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Cambridge CB1 8RN, England.;Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Oncol, Cambridge, England.4 aut |
700 | 1 | a Hemingway, Harryu UCL, Inst Hlth Informat, London, England.;UCL, Hlth Data Res UK, London, England.;Univ Coll London Hosp, Biomed Res Ctr UCLH BRC, London, England.;Alan Turing Inst, London, England.4 aut |
700 | 1 | a Hamann, Uteu German Canc Res Ctr, Mol Genet Breast Canc, D-69120 Heidelberg, Germany.4 aut |
700 | 1 | a Kuchenbaecker, Karoline B.u UCL, Div Psychiat, London, England.;UCL, UCL Genet Inst, London, England.4 aut |
710 | 2 | a UCL, Inst Hlth Informat, London, England.b University College London4 org |
773 | 0 | t Genome Medicined : BioMed Central (BMC)g 15q 15x 1756-994X |
856 | 4 | u https://doi.org/10.1186/s13073-022-01152-5y Fulltext |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1745196/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u http://dx.doi.org/10.1186/s13073-022-01152-5x freey FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-498948 |
856 | 4 8 | u https://doi.org/10.1186/s13073-022-01152-5 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:152000895 |
856 | 4 8 | u https://lup.lub.lu.se/record/03b290d6-d650-490a-9e52-2fcb867a25b3 |
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