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Rapid gene content ...
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Schlebusch, Stephen A.Charles Univ Prague, Fac Sci, Dept Zool, Prague, Czech Republic.
(författare)
Rapid gene content turnover on the germline-restricted chromosome in songbirds
- Artikel/kapitelEngelska2023
Förlag, utgivningsår, omfång ...
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Springer Nature,2023
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electronicrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:uu-510143
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-510143URI
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https://doi.org/10.1038/s41467-023-40308-8DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Songbirds have an extra chromosome with unknown function found only in their germline. This study assembles and compares this chromosome in two closely related nightingale species, finding large differences in genetic content and only one conserved gene with probable essential function. The germline-restricted chromosome (GRC) of songbirds represents a taxonomically widespread example of programmed DNA elimination. Despite its apparent indispensability, we still know very little about the GRC's genetic composition, function, and evolutionary significance. Here we assemble the GRC in two closely related species, the common and thrush nightingale. In total we identify 192 genes across the two GRCs, with many of them present in multiple copies. Interestingly, the GRC appears to be under little selective pressure, with the genetic content differing dramatically between the two species and many GRC genes appearing to be pseudogenized fragments. Only one gene, cpeb1, has a complete coding region in all examined individuals of the two species and shows no copy number variation. The acquisition of this gene by the GRC corresponds with the earliest estimates of the GRC origin, making it a good candidate for the functional indispensability of the GRC in songbirds.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Ridl, JakubCharles Univ Prague, Fac Sci, Dept Zool, Prague, Czech Republic.;Czech Acad Sci, Inst Mol Genet, Prague, Czech Republic.
(författare)
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Poignet, ManonCharles Univ Prague, Fac Sci, Dept Zool, Prague, Czech Republic.
(författare)
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Ruiz-Ruano, Francisco J.Uppsala universitet,Systematisk biologi,Science for Life Laboratory, SciLifeLab,Univ East Anglia, Sch Biol Sci, Norwich, England.;Univ Bonn, Inst Evolutionary Biol & Ecol, An Immenburg 1, D-53121 Bonn, Germany.;Leibniz Inst Anal Biodivers Change, Ctr Mol Biodivers Res, Adenauerallee 127, D-53113 Bonn, Germany.(Swepub:uu)fraru543
(författare)
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Reif, JiriCharles Univ Prague, Inst Environm Studies, Fac Sci, Prague, Czech Republic.;Palacky Univ, Fac Sci, Dept Zool, Olomouc, Czech Republic.
(författare)
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Pajer, PetrMil Hlth Inst, Mil Med Agcy, Tychonova 1, San Antonio 16001, Czech Republic.
(författare)
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Paces, JanCzech Acad Sci, Inst Mol Genet, Prague, Czech Republic.
(författare)
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Albrecht, TomasCharles Univ Prague, Fac Sci, Dept Zool, Prague, Czech Republic.;Czech Acad Sci, Inst Vertebrate Biol, Brno, Czech Republic.
(författare)
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Suh, AlexanderUppsala universitet,Science for Life Laboratory, SciLifeLab,Systematisk biologi,Univ East Anglia, Sch Biol Sci, Norwich, England.;Leibniz Inst Anal Biodivers Change, Ctr Mol Biodivers Res, Adenauerallee 127, D-53113 Bonn, Germany.(Swepub:uu)alesu519
(författare)
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Reifova, RadkaCharles Univ Prague, Fac Sci, Dept Zool, Prague, Czech Republic.
(författare)
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Charles Univ Prague, Fac Sci, Dept Zool, Prague, Czech Republic.Charles Univ Prague, Fac Sci, Dept Zool, Prague, Czech Republic.;Czech Acad Sci, Inst Mol Genet, Prague, Czech Republic.
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Nature Communications: Springer Nature14:12041-1723
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Schlebusch, Step ...
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Ridl, Jakub
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Poignet, Manon
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Ruiz-Ruano, Fran ...
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Reif, Jiri
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Pajer, Petr
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visa fler...
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Paces, Jan
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Albrecht, Tomas
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Suh, Alexander
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Reifova, Radka
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visa färre...
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