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High prevalence of ...
High prevalence of interstitial lung abnormalities in middle-aged never-smokers
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- Pesonen, Ida (författare)
- Karolinska Institute,Karolinska Institutet,Karolinska Inst, Sweden; Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden,Respiratory Medicine Unit, Department of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden; Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden
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- Johansson, Fredrik (författare)
- Danderyd Hosp, Sweden,Medical Library, Danderyd Hospital, Stockholm, Sweden
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- Johnsson, Åse (Allansdotter), 1966 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology,Region Västra Götaland, Sahlgrenska University Hospital, Department of Radiology, Gothenburg, Sweden; Department of Radiology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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- Blomberg, Anders, 1961- (författare)
- Umeå universitet,Umeå University,Avdelningen för medicin
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- Boijsen, Marianne, 1948 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology,Region Västra Götaland, Sahlgrenska University Hospital, Department of Radiology, Gothenburg, Sweden; Department of Radiology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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- Brandberg, John, 1966 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology,Region Västra Götaland, Sahlgrenska University Hospital, Department of Radiology, Gothenburg, Sweden; Department of Radiology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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- Cederlund, Kerstin (författare)
- Karolinska Institute,Karolinska Institutet,Karolinska Inst, Sweden,Department of Clinical Science, Intervention and Technology, Karolinska Institute, Stockholm, Sweden
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- Egesten, Arne (författare)
- Lund University,Lunds universitet,Lungmedicin, allergologi och palliativ medicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Nya strategier för att förhindra skadlig luftvägsinflammation,Forskargrupper vid Lunds universitet,Hereditärt angioödem (HAE) – epidemiologi, genetik och patofysiologi,Respiratory Medicine, Allergology, and Palliative Medicine,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Novel strategies targeting detrimental airway inflammation,Lund University Research Groups,Hereditary angioedema (HAE) – epidemiology, genetics and pathophysiology,Respiratory Medicine, Allergology and Palliative Medicine, Department of Clinical Sciences Lund, Lund University and Skåne University Hospital, Lund, Sweden
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- Emilsson, Össur Ingi (författare)
- Uppsala University,Uppsala universitet,Lung- allergi- och sömnforskning,Faculty of Medicine, University of Iceland, Reykjavik, Iceland; Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden,Univ Iceland, Iceland; Uppsala Univ, Sweden
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- Engvall, Jan (författare)
- Linköping University,Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Fysiologiska kliniken US,CMIV, Centre of Medical Image Science and Visualization, Linköping University, Linköping, Sweden; Department of Clinical Physiology, Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden
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- Frølich, Andreas (författare)
- Umeå universitet,Umeå University,Avdelningen för medicin
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- Hagström, Emil (författare)
- Uppsala University,Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR),Uppsala Univ, Sweden; Uppsala Univ, Sweden,Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden
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- Lindberg, Eva (författare)
- Uppsala University,Uppsala universitet,Lung- allergi- och sömnforskning,Uppsala Univ, Sweden,Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden
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- Malinovschi, Andrei, 1978- (författare)
- Uppsala University,Uppsala universitet,Klinisk fysiologi,Umea Univ, Sweden; Uppsala Univ, Sweden,Department of Medical Sciences, Clinical Physiology, Uppsala University, Sweden
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- Stenfors, Nikolai (författare)
- Umeå universitet,Umeå University,Avdelningen för medicin
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- Swahn, Eva (författare)
- Linköping University,Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US,Department of Cardiology and Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden
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- Tanash, Hanan (författare)
- Lund University,Lunds universitet,Medicin/akutsjukvård, Lund,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Medicine, Lund,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Internal Medicine - Epidemiology,Lund University Research Groups,Department of Respiratory Medicine, Skåne University Hospital, Lund University, Malmö, Sweden
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- Themudo, Raquel (författare)
- Karolinska Institutet,Karolinska Inst, Sweden; Karolinska Univ Hosp Huddinge, Sweden,Department of Clinical Science, Intervention and Technology at Karolinska Institute, Division of Medical Imaging and Technology, Stockholm, Sweden; Department of Radiology, Karolinska University Hospital in Huddinge, Stockholm, Sweden
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- Torén, Kjell, 1952 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Section of Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
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- Vanfleteren, Lowie E G W (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,COPD Center, Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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- Wollmer, Per (författare)
- Lund University,Lunds universitet,Klinisk fysiologi och nuklearmedicin, Malmö,Forskargrupper vid Lunds universitet,LTH profilområde: Aerosoler,LTH profilområden,Lunds Tekniska Högskola,Clinical Physiology and Nuclear Medicine, Malmö,Lund University Research Groups,LTH Profile Area: Aerosols,LTH Profile areas,Faculty of Engineering, LTH,Department of Translational Medicine, Lund University, Lund, Sweden
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- Zaigham, Suneela (författare)
- Uppsala University,Lund University,Lunds universitet,Uppsala universitet,Klinisk fysiologi,Department of Medical Sciences, Clinical Physiology, Uppsala University, Sweden; Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden,Lund Univ, Sweden,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups
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- Östgren, Carl Johan (författare)
- Linköping University,Linköpings universitet,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Vårdcentralen Ekholmen,CMIV, Centre of Medical Image Science and Visualization, Linköping University, Linköping, Sweden; Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden
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- Sköld, C. Magnus (författare)
- Karolinska Institute,Karolinska Institutet,Karolinska Inst, Sweden; Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden,Respiratory Medicine Unit, Department of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden; Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden
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(creator_code:org_t)
- European Respiratory Society, 2023
- 2023
- Engelska.
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Ingår i: ERJ Open Research. - : European Respiratory Society. - 2312-0541. ; 9:5
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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http://dx.doi.org/10... (free)
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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https://urn.kb.se/re...
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https://lup.lub.lu.s...
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https://gup.ub.gu.se...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Interstitial lung abnormalities (ILA) are incidental findings on chest computed tomography (CT). These patterns can present at an early stage of fibrotic lung disease. Our aim was to estimate the prevalence of ILA in the Swedish population, in particular in never-smokers, and find out its association with demographics, comorbidities and symptoms.METHODS: Participants were recruited to the Swedish CArdioPulmonary BioImage Study (SCAPIS), a population-based survey including men and women aged 50-64 years performed at six university hospitals in Sweden. CT scan, spirometry and questionnaires were performed. ILA were defined as cysts, ground-glass opacities, reticular abnormality, bronchiectasis and honeycombing.FINDINGS: Out of 29 521 participants, 14 487 were never-smokers and 14 380 were men. In the whole population, 2870 (9.7%) had ILA of which 134 (0.5%) were fibrotic. In never-smokers, the prevalence was 7.9% of which 0.3% were fibrotic. In the whole population, age, smoking history, chronic bronchitis, cancer, coronary artery calcium score and high-sensitive C-reactive protein were associated with ILA. Both ILA and fibrotic ILA were associated with restrictive spirometric pattern and impaired diffusing capacity of the lung for carbon monoxide. However, individuals with ILA did not report more symptoms compared with individuals without ILA.INTERPRETATION: ILA are common in a middle-aged Swedish population including never-smokers. ILA may be at risk of being underdiagnosed among never-smokers since they are not a target for screening.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Fysiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Physiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- Lungmedicin
- Lung Medicine
- Clinical Physiology
- Klinisk fysiologi
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Pesonen, Ida
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Johansson, Fredr ...
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Johnsson, Åse (A ...
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Blomberg, Anders ...
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Boijsen, Mariann ...
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Brandberg, John, ...
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visa fler...
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Cederlund, Kerst ...
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Egesten, Arne
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Emilsson, Össur ...
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Engvall, Jan
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Frølich, Andreas
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Hagström, Emil
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Lindberg, Eva
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Malinovschi, And ...
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Stenfors, Nikola ...
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Swahn, Eva
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Tanash, Hanan
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Themudo, Raquel
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Torén, Kjell, 19 ...
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Vanfleteren, Low ...
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Wollmer, Per
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Zaigham, Suneela
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Östgren, Carl Jo ...
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Sköld, C. Magnus
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Lungmedicin och ...
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MEDICIN OCH HÄLS ...
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och Medicinska och f ...
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och Fysiologi
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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Uppsala universitet
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Karolinska Institutet
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Linköpings universitet
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Lunds universitet
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Göteborgs universitet
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Umeå universitet