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Detection and corre...
Detection and correction of patient motion in dynamic 15O-water PET MPI.
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Christensen, Nana L (författare)
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- Nordström, Jonny (författare)
- Uppsala universitet,Radiologi
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Madsen, Simon (författare)
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Madsen, Michael A (författare)
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Gormsen, Lars C (författare)
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- Kero, Tanja (författare)
- Uppsala universitet,Radiologi
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- Lubberink, Mark (författare)
- Uppsala universitet,Radiologi
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Tolbod, Lars P (författare)
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(creator_code:org_t)
- Elsevier, 2023
- 2023
- Engelska.
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Ingår i: Journal of Nuclear Cardiology. - : Elsevier. - 1071-3581 .- 1532-6551. ; 30:6, s. 2736-2749
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Patient motion constitutes a limitation to 15O-water cardiac PET imaging. We examined the ability of image readers to detect and correct patient motion using simulated motion data and clinical patient scans.METHODS: Simulated data consisting of 16 motions applied to 10 motion-free scans were motion corrected using two approaches, pre-analysis and post-analysis for motion identification. Both approaches employed a manual frame-by-frame correction method. In addition, a clinical cohort was analyzed for assessment of prevalence and effect of motion and motion correction.RESULTS: Motion correction was performed on 94% (pre-analysis) and 64% (post-analysis) of the scans. Large motion artifacts were corrected in 91% (pre-analysis) and 74% (post-analysis) of scans. Artifacts in MBF were reduced in 56% (pre-analysis) and 58% (post-analysis) of the scans. The prevalence of motion in the clinical patient cohort (n = 762) was 10%. Motion correction altered exam interpretation in only 10 (1.3%) clinical patient exams.CONCLUSION: Frame-by-frame motion correction after visual inspection is useful in reducing motion artifacts in cardiac 15O-water PET. Reviewing the initial results (parametric images and polar maps) as part of the motion correction process, reduced erroneous corrections in motion-free scans. In a large clinical cohort, the impact of motion correction was limited to few patients.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Nyckelord
- PET
- image analysis
- myocardial blood flow
- perfusion agents
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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