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Otitis media :
Otitis media : Interactions between host and environment, immune and inflammatory responses
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- Nokso-Koivisto, Johanna (författare)
- Univ Helsinki, Helsinki Univ Hosp, Dept Otorhinolaryngol, Helsinki, Finland.;Helsinki Univ Hosp, Dept Otorhinolaryngol, POB 263, Helsinki 00290, Finland.,Helsinki University Central Hospital
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- Ehrlich, Garth D. (författare)
- Drexel Univ, Coll Med, Dept Microbiol & Immunol, Philadelphia, PA USA.;Drexel Univ, Coll Med, Dept Otolaryngol Head & Neck Surg, Philadelphia, PA USA.,Drexel University
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- Enoksson, Frida (författare)
- Lund University,Lunds universitet,Kliniska Vetenskaper, Helsingborg,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Clinical Sciences, Helsingborg,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Komatsu, Kensei (författare)
- Georgia State Univ, Inst Biomed Sci, Ctr Inflammat Immun & Infect, Atlanta, GA USA.,Georgia State University
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- Mason, Kevin (författare)
- Ohio State Univ, Res Inst Nationwide Childrens Hosp, Infect Dis Inst, Sch Med, Columbus, OH USA.,Ohio State University
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- Melhus, Åsa (författare)
- Uppsala University,Uppsala universitet,Klinisk mikrobiologi
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- Patel, Janak A. (författare)
- Univ Texas, Med Branch, Dept Infect Control & Healthcare Epidemiol, Galveston, TX USA.;Univ Texas, Dept Pediat, Div Pediat Infect Dis, Med Branch, Galveston, TX USA.,University of Texas Medical Branch
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- Vijayasekaran, Shiyan (författare)
- Univ Western Australia, Perth Childrens Hosp, Perth ENT Ctr, Perth, Australia.,University of Western Australia, Perth
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- Ryan, Allen (författare)
- Univ Calif San Diego, Dept Surg, Div Otolaryngol, San Diego, CA USA.,University of California, San Diego
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Univ Helsinki, Helsinki Univ Hosp, Dept Otorhinolaryngol, Helsinki, Finland;Helsinki Univ Hosp, Dept Otorhinolaryngol, POB 263, Helsinki 00290, Finland. Helsinki University Central Hospital (creator_code:org_t)
- Elsevier, 2024
- 2024
- Engelska.
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Ingår i: International Journal of Pediatric Otorhinolaryngology. - : Elsevier. - 0165-5876 .- 1872-8464. ; 176
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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http://dx.doi.org/10... (free)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- ObjectiveTo review and highlight progress in otitis media (OM) research in the areas of immunology, inflammation, environmental influences and host-pathogen responses from 2019 to 2023. Opportunities for innovative future research were also identified.Data sourcesPubMed database of the National Library of Medicine.Review methodsKey topics were assigned to each panel member for detailed review. Search of the literature was from June 2019 until February 2023. Draft reviews were collated, circulated, and discussed among panel members at the 22nd International Symposium on Recent Advances in Otitis Media in June 2023. The final manuscript was prepared and approved by all the panel members.ConclusionsImportant advances were identified in: environmental influences that enhance OM susceptibility; polymicrobial middle ear (ME) infections; the role of adaptive immunity defects in otitis-proneness; additional genes linked to OM; leukocyte contributions to OM pathogenesis and recovery; and novel interventions in OM based on host responses to infection. Innovative areas of research included: identification of novel bacterial genes and pathways important for OM persistence, bacterial adaptations and evolution that enhance chronicity; animal and human ME gene expression, including at the single-cell level; and Sars-CoV-2 infection of the ME and Eustachian tube.d
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Mikrobiologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Microbiology in the medical area (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Oto-rhino-laryngologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Otorhinolaryngology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Nyckelord
- Otitis media
- Immunology
- Inflammatory
- Bacteria
- Virus
- Environment
- Bacteria
- Environment
- Immunology
- Inflammatory
- Otitis media
- Virus
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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