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Insights into healt...
Insights into health promoting effects and myochemical profiles of pine mushroom Tricholoma matsutake
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- Zhou, Yifan (författare)
- ABNU HKBU United Int Coll, Food Sci & Technol Program, Zhuhai, Peoples R China.;Natl Univ Singapore, Dept Food Sci & Technol, Singapore, Singapore.
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- El-Seedi, Hesham R. (författare)
- Uppsala universitet,Farmakognosi
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- Xu, Baojun (författare)
- ABNU HKBU United Int Coll, Food Sci & Technol Program, Zhuhai, Peoples R China.
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ABNU HKBU United Int Coll, Food Sci & Technol Program, Zhuhai, Peoples R China;Natl Univ Singapore, Dept Food Sci & Technol, Singapore, Singapore. Farmakognosi (creator_code:org_t)
- 2022-01-05
- 2023
- Engelska.
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Ingår i: Critical reviews in food science and nutrition. - : Taylor & Francis. - 1040-8398 .- 1549-7852. ; 63:22, s. 5698-5723
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Tricholoma matsutake (TM) is a valuable edible mushroom that has attracted increasing attention due to its potential medicinal values and functional uses. However, the chemical composition and molecular mechanisms behinds TM are not specifically summarized yet. Hence, this review aims to systematically analyze the research progress on the characterization of chemical compositions and the reported health effects of TM in the last 20 years. The myochemical profiles of TM consist of proteins with amino acids, fatty acids, nucleic acids with their derivatives, polysaccharides, minerals, volatile components, phenolic compounds, and steroids. The bioactive substances in TM exert their health effects mainly by regulating body immunity and restoring the balance of the redox system. NF-kappa B signaling pathway and its downstream cytokines such as TNF-alpha and IL-6 are the key molecular mechanisms. In addition, MAPK, PI3K-Akt, and JAK-STAT are also involved. NF-kappa B, MAPK, and PI3K-Akt are also highly related to cancer regulation and thus TM has great anticancer potential. Considering that most studies have only investigated the dosage and inhibition rate of TM on cancer cell lines, more extensive studies need to focus on the specific molecular mechanisms behind these anticancer effects in the future.
Ämnesord
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
Nyckelord
- Anti-tumor
- chemical composition
- immunity regulation
- inflammation response
- NF-kappa B
- Tricholoma matsutake
Publikations- och innehållstyp
- ref (ämneskategori)
- for (ämneskategori)
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