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Innovative cellular...
Innovative cellular therapies for autoimmune diseases : expert-based position statement and clinical practice recommendations from the EBMT practice harmonization and guidelines committee
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- Greco, Raffaella (författare)
- Univ Vita Salute San Raffaele, IRCCS San Raffaele Hosp, Unit Hematol & Bone Marrow Transplantat, Milan, Italy.;Practice Harmonizat & Guidelines Comm EBMT, Barcelona, Spain.;ADWP EBMT, Barcelona, Spain.;Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Hematol & Bone Marrow Transplantat Unit, Via Olgettina 60, I-20132 Milan, Italy.
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- Alexander, Tobias (författare)
- Charite Univ Med Berlin, Berlin, Germany.;Free Univ Berlin, Berlin, Germany.;Humboldt Univ, Berlin, Germany.;Berlin Inst Hlth, Dept Rheumatol & Clin Immunol, Berlin, Germany.
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- Del Papa, Nicoletta (författare)
- Univ Milan, Rheumatol Dept, Scleroderma Clin, ASST G Pini CTO, Milan, Italy.
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- Mueller, Fabian (författare)
- Univ Hosp Erlangen, Dept Internal Med Hematol & Oncol 5, Erlangen, Germany.;Bayr Zentrum Krebsforsch BZKF, Erlangen, Germany.
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- Saccardi, Riccardo (författare)
- Careggi Univ Hosp, Cellular Therapies & Transfus Med Unit, Florence, Italy.
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- Sanchez-Guijo, Fermin (författare)
- Univ Salamanca, IBSAL Univ Hosp Salamanca, Dept Hematol, Salamanca, Spain.;Univ Salamanca, Dept Med, Salamanca, Spain.
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- Schett, Georg (författare)
- FAU Erlangen Nurnberg, Dept Internal Med Rheumatol & Immunol 3, Erlangen, Germany.;Univ Klinikum Erlangen, Erlangen, Germany.;Friedrich Alexander Univ FAU Erlangen Nurnberg, Deutsch Zentrum Immuntherapie, Univ Klinikum Erlangen, Erlangen, Germany.
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- Sharrack, Basil (författare)
- Sheffield Teaching Hosp NHS Fdn Trust, Dept Neurosci & Sheffield NIHR Translat Neurosci B, Sheffield, England.;Univ Sheffield, Sheffield, England.
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- Snowden, John A. (författare)
- Univ Sheffield, Sheffield Teaching Hosp NHS Fdn Trust, Sch Med & Populat Hlth, Dept Haematol,Div Clin Med, Sheffield, England.
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- Tarte, Karin (författare)
- Univ Rennes, SITI Lab, CHU Rennes, EFS Bretagne, Rennes, France.
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- Onida, Francesco (författare)
- Univ Milan, Hematol & ASCT Unit, ASST Fatebenefratelli Sacco, Milan, Italy.;Practice Harmonizat & Guidelines Comm EBMT, Barcelona, Spain.
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- Sanchez-Ortega, Isabel (författare)
- Secretary Practice Harmonizat & Guidelines Comm EB, Barcelona, Spain.;Execut Off, Barcelona, Spain.
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- Burman, Joachim, 1974- (författare)
- Uppsala universitet,Institutionen för medicinska vetenskaper
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- Llorente, Cristina Castilla (författare)
- Gustave Roussy, Hematol Dept, Villejuif, France.
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- Cervera, Ricard (författare)
- Hosp Clin Barcelona, Reference Ctr Syst Autoimmune Dis UEC CSUR, Dept Autoimmune Dis, Catalan & Spanish Hlth Syst ERN ReCONNET, ,Catalonia, Barcelona, Catalonia, Spain.
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- Ciceri, Fabio (författare)
- Univ Vita Salute San Raffaele, IRCCS San Raffaele Hosp, Unit Hematol & Bone Marrow Transplantat, Milan, Italy.
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- Doria, Andrea (författare)
- Univ Padua, Dept Med DiMED, Rheumatol Unit, Padua, Italy.
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- Henes, Joerg (författare)
- Univ Hosp Tuebingen, Ctr Interdisciplinary Rheumatol Immunol & Autoimmu, Tubingen, Germany.;Univ Hosp Tuebingen, Dept Internal Med Haematol Oncol Clin Immunol & Rh, Tubingen, Germany.
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- Lindsay, James (författare)
- Royal London Hosp, Dept Gastroenterol, Barts Hlth NHS Trust, London, England.;Queen Mary Univ London, Blizard Inst, Ctr Immunobiol, Barts & London Sch Med & Dent, London, England.
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- Mackensen, Andreas (författare)
- Univ Hosp Erlangen, Dept Internal Med Hematol & Oncol 5, Erlangen, Germany.
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- Muraro, Paolo A. (författare)
- Imperial Coll London, Dept Brain Sci, London, England.
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- Ricart, Elena (författare)
- Hosp Clin Barcelona, Inst Invest Biomed August Pi & Sunyer IDIBAPS, Ctr Invest Biomed Red Enfermedades Hepat & Digest, Gastroenterol Dept, Barcelona, Spain.
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- Rovira, Montserrat (författare)
- Univ Barcelona, Hosp Clin, Inst Haematol & Oncol, Haematol Dept,BMT Unit,IDIBAPS, Barcelona, Spain.;Josep Carreras Leukaemia Res Fdn, Barcelona, Spain.
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- Zuckerman, Tsila (författare)
- Technion, Rambam Hlth Care Campus & Rappaport Fac Med, Haifa, Israel.
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- Yakoub-Agha, Ibrahim (författare)
- Univ Lille, CHU Lille, INSERM, U1286,Infinite, F-59000 Lille, France.;Practice Harmonizat & Guidelines Comm EBMT, Barcelona, Spain.
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- Farge, Dominique (författare)
- Paris Cite Univ, St Louis Hosp, Ctr Reference Malad Autoimmunes Syst Rares Ile De, Internal Med Unit 04,CRMR MATHEC,AP HP,Malad Autoi, Paris, France.;McGill Univ, Dept Med, Montreal, PQ, Canada.;St Louis Hosp, AP HP, Malad Autoimmunes & Therapie Cellulaire, Internal Med Unit UF CRMR MATHEC 04, 1 Ave Claude Vellefaux, F-75010 Paris, France.
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Univ Vita Salute San Raffaele, IRCCS San Raffaele Hosp, Unit Hematol & Bone Marrow Transplantat, Milan, Italy;Practice Harmonizat & Guidelines Comm EBMT, Barcelona, Spain.;ADWP EBMT, Barcelona, Spain.;Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Hematol & Bone Marrow Transplantat Unit, Via Olgettina 60, I-20132 Milan, Italy. Charite Univ Med Berlin, Berlin, Germany.;Free Univ Berlin, Berlin, Germany.;Humboldt Univ, Berlin, Germany.;Berlin Inst Hlth, Dept Rheumatol & Clin Immunol, Berlin, Germany. (creator_code:org_t)
- Elsevier, 2024
- 2024
- Engelska.
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Ingår i: eClinicalMedicine. - : Elsevier. - 2589-5370. ; 69
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Autoimmune diseases (ADs) are characterized by loss of immune tolerance, high chronicity, with substantial morbidity and mortality, despite conventional immunosuppression (IS) or targeted disease modifying therapies (DMTs), which usually require repeated administration. Recently, novel cellular therapies (CT), including mesenchymal stromal cells (MSC), Chimeric Antigen Receptors T cells (CART) and regulatory T cells (Tregs), have been successfully adopted in ADs. An international expert panel of the European Society for Blood and Marrow Transplantation and the International Society for the Cell and Gene Therapy, reviewed all available evidence, based on the current literature and expert practices, on use of MSC, CART and Tregs, in AD patients with rheumatological, neurological, and gastroenterological indications. Expert -based consensus and recommendations for best practice and quality of patient care were developed to support clinicians, scientists, and their multidisciplinary teams, as well as patients and care providers and will be regularly updated. Copyright (c) 2024 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY -NC -ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Hematologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Hematology (hsv//eng)
Nyckelord
- Autoimmune diseases
- Mesenchymal stem cells
- Regulatory T cells
- Chimeric antigen receptor (CAR) T cells
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Greco, Raffaella
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Alexander, Tobia ...
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Del Papa, Nicole ...
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Mueller, Fabian
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Saccardi, Riccar ...
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Sanchez-Guijo, F ...
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visa fler...
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Schett, Georg
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Sharrack, Basil
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Snowden, John A.
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Tarte, Karin
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Onida, Francesco
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Sanchez-Ortega, ...
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Burman, Joachim, ...
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Llorente, Cristi ...
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Cervera, Ricard
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Ciceri, Fabio
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Doria, Andrea
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Henes, Joerg
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Lindsay, James
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Mackensen, Andre ...
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Muraro, Paolo A.
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Ricart, Elena
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Rovira, Montserr ...
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Zuckerman, Tsila
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Yakoub-Agha, Ibr ...
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Farge, Dominique
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