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The posterity of Ze...
The posterity of Zebrafish in paradigm of in vivo molecular toxicological profiling
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- Verma, Suresh K. (författare)
- KIIT Univ, Sch Biotechnol, Bhubaneswar, India.
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- Nandi, Aditya (författare)
- KIIT Univ, Sch Biotechnol, Bhubaneswar, India.
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- Sinha, Adrija (författare)
- KIIT Univ, Sch Biotechnol, Bhubaneswar, India.
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- Patel, Paritosh (författare)
- KIIT Univ, Sch Biotechnol, Bhubaneswar, India.;Kwangwoon Univ, Plasma Biosci Res Ctr, Dept Elect & Biol Phys, Seoul 01897, South Korea.
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- Mohanty, Swabhiman (författare)
- KIIT Univ, Sch Biotechnol, Bhubaneswar, India.
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- Jha, Ealisha (författare)
- KIIT Univ, Sch Biotechnol, Bhubaneswar, India.
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- Jena, Snehasmita (författare)
- KIIT Univ, Sch Biotechnol, Bhubaneswar, India.
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- Kumari, Puja (författare)
- Masaryk Univ, Fac Sci, RECETOX, Kotlarska 2, Brno 61137, Czech Republic.
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- Ghosh, Aishee (författare)
- KIIT Univ, Sch Biotechnol, Bhubaneswar, India.
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- Jerman, Ivan (författare)
- Natl Inst Chem, Hajdrihova 19, Ljubljana 1000, Slovenia.
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- Chouhan, Raghuraj Singh (författare)
- Jozef Stefan Inst, Dept Environm Sci, Jamova 39, Ljubljana 1000, Slovenia.
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- Dutt, Ateet (författare)
- Univ Nacl Autonoma Mexico, Inst Invest Mat, Mexico City, Mexico.
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- Samal, Shailesh Kumar (författare)
- Karolinska Inst, Inst Environm Med, Unit Immunol & Chron Dis, S-17177 Stockholm, Sweden.
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- Mishra, Yogendra Kumar (författare)
- Univ Southern Denmark, NanoSYD, Mads Clausen Inst, Alsion 2, DK-6400 Sonderborg, Denmark.
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- Varma, Rajender S. (författare)
- Tech Univ Liberec TUL, Inst Nanomat, Adv Technol & Innovat CxI, Studentska 1402-2, Liberec 1, Czech Republic.
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- Panda, Pritam Kumar, PhD Student, 1991- (författare)
- Uppsala universitet,Materialteori
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- Kaushik, Nagendra Kumar (författare)
- Kwangwoon Univ, Plasma Biosci Res Ctr, Dept Elect & Biol Phys, Seoul 01897, South Korea.
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- Singh, Deobrat (författare)
- Uppsala universitet,Materialteori
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- Suar, Mrutyunjay (författare)
- KIIT Univ, Sch Biotechnol, Bhubaneswar, India.
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KIIT Univ, Sch Biotechnol, Bhubaneswar, India KIIT Univ, Sch Biotechnol, Bhubaneswar, India.;Kwangwoon Univ, Plasma Biosci Res Ctr, Dept Elect & Biol Phys, Seoul 01897, South Korea. (creator_code:org_t)
- Elsevier, 2024
- 2024
- Engelska.
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Ingår i: Biomedicine and Pharmacotherapy. - : Elsevier. - 0753-3322 .- 1950-6007. ; 171
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- The aggrandised advancement in utility of advanced day-to-day materials and nanomaterials has raised serious concern on their biocompatibility with human and other biotic members. In last few decades, understanding of toxicity of these materials has been given the centre stage of research using many in vitro and in vivo models. Zebrafish (Danio rerio), a freshwater fish and a member of the minnow family has garnered much attention due to its distinct features, which make it an important and frequently used animal model in various fields of embryology and toxicological studies. Given that fertilization and development of zebrafish eggs take place externally, they serve as an excellent model organism for studying early developmental stages. Moreover, zebrafish possess a comparable genetic composition to humans and share almost 70% of their genes with mammals. This particular model organism has become increasingly popular, especially for developmental research. Moreover, it serves as a link between in vitro studies and in vivo analysis in mammals. It is an appealing choice for vertebrate research, when employing high-throughput methods, due to their small size, swift development, and relatively affordable laboratory setup. This small vertebrate has enhanced comprehension of pathobiology and drug toxicity. This review emphasizes on the recent developments in toxicity screening and assays, and the new insights gained about the toxicity of drugs through these assays. Specifically, the cardio, neural, and, hepatic toxicology studies inferred by applications of nanoparticles have been highlighted.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)
- NATURVETENSKAP -- Biologi -- Utvecklingsbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Developmental Biology (hsv//eng)
Nyckelord
- Zebrafish
- Toxicity
- Cardiotoxicity
- Neurotoxicity
- Hepatotoxicity
- Drug screening
- Nanoparticles
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Verma, Suresh K.
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Nandi, Aditya
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Sinha, Adrija
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Patel, Paritosh
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Mohanty, Swabhim ...
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Jha, Ealisha
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visa fler...
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Jena, Snehasmita
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Kumari, Puja
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Ghosh, Aishee
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Jerman, Ivan
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Chouhan, Raghura ...
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Dutt, Ateet
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Samal, Shailesh ...
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Mishra, Yogendra ...
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Varma, Rajender ...
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Panda, Pritam Ku ...
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Kaushik, Nagendr ...
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Singh, Deobrat
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Suar, Mrutyunjay
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Uppsala universitet
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Karolinska Institutet