Atypical focal non-neoplastic brain changes in neurofibromatosis type 1 : mass effect and contrast enhancement

• Children and young adults with neurofibromatosis type 1 often have small high-signal foci on T2-weighted images of the brain. We describe follow-up of two patients in whom one of the foci had atypical features, commonly regarded as signs of a neoplasm. In the first, one lesion showed temporary contrast enhancement and decreasing mass effect. The second developed an expanding lesion that increased minimally in size over 4.5 year's follow-up. The borderline between neoplastic and non-neoplastic lesions seems to be indistinct.

Nyckelord

Neurofibromatosis

Brain tumours

Magnetic resonance imaging

MEDICINE

MEDICIN

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