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Cognitive decline i...
Cognitive decline in patients with symptomtic HIV-1 infection : No decline in asymptomatic infection
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Poutiainen, E. (författare)
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Elovaara, I. (författare)
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- Raininko, Raili (författare)
- Uppsala universitet,Institutionen för onkologi, radiologi och klinisk immunologi,RAD
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visa fler...
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Vilkki, J. (författare)
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Lähdevirta, J. (författare)
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Iivanainen, M. (författare)
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visa färre...
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(creator_code:org_t)
- 1996
- 1996
- Engelska.
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Ingår i: Acta Neurologica Scandinavica. - 0001-6314 .- 1600-0404. ; 93:6, s. 421-7
- Relaterad länk:
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https://urn.kb.se/re...
Abstract
Ämnesord
Stäng
- Thirty-six HIV-1-infected predominantly well-functioning subjects were followed up for one year by repeated neuropsychological, clinical neurological, neuroradiological, and immunological examinations. Changes in cognitive performance related to the severity of HIV-1 infection as well as to neuroradiological or immunological changes were studied. A decline in cognitive speed and flexibility was found in symptomatic subjects (ARC, AIDS). The impairment was especially pronounced in patients with progression of brain atrophy. These findings suggest a brain pathology underlying the cognitive decline in ambulatory outpatients with symptomatic HIV-1 infection. A practice effect was found in asymptomatic subjects (ASX, LAS) and in those with unchanged CT/MRI scans. No systematic relationship was found between cognitive change and immunological change.
Nyckelord
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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