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Optimal Oxygen Conc...
Optimal Oxygen Concentration during Induction of General Anesthesia
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- Edmark, Lennart, 1954- (författare)
- Uppsala universitet,Klinisk fysiologi
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Kostova-Aherdan, Kamelia (författare)
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- Enlund, Mats (författare)
- Department of Anesthesiology and Intensive Care, Central Hospital, Västerås, Sweden
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visa fler...
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- Hedenstierna, Göran (författare)
- Uppsala universitet,Klinisk fysiologi
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visa färre...
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(creator_code:org_t)
- 2003
- 2003
- Engelska.
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Ingår i: Anesthesiology. - 0003-3022 .- 1528-1175. ; 98:1, s. 28-33
- Relaterad länk:
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https://urn.kb.se/re...
Abstract
Ämnesord
Stäng
- BACKGROUND:The use of 100% oxygen during induction of anesthesia may produce atelectasis. The authors investigated how different oxygen concentrations affect the formation of atelectasis and the fall in arterial oxygen saturation during apnea.METHODS:Thirty-six healthy, nonsmoking women were randomized to breathe 100, 80, or 60% oxygen for 5 min during the induction of general anesthesia. Ventilation was then withheld until the oxygen saturation, assessed by pulse oximetry, decreased to 90%. Atelectasis formation was studied with computed tomography.RESULTS:Atelectasis in a transverse scan near the diaphragm after induction of anesthesia and apnea was 9.8 +/- 5.2 cm2 (5.6 +/- 3.4% of the total lung area; mean +/- SD), 1.3 +/- 1.2 cm2 (0.6 +/- 0.7%), and 0.3 +/- 0.3 cm2 (0.2 +/- 0.2%) in the groups breathing 100, 80, and 60% oxygen, respectively (P < 0.01). The corresponding times to reach 90% oxygen saturation were 411 +/- 84, 303 +/- 59, and 213 +/- 69 s, respectively (P < 0.01).CONCLUSION:During routine induction of general anesthesia, 80% oxygen for oxygenation caused minimal atelectasis, but the time margin before unacceptable desaturation occurred was significantly shortened compared with 100% oxygen.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
Nyckelord
- Anestesiologi
- Anaesthesiology
Publikations- och innehållstyp
- vet (ämneskategori)
- art (ämneskategori)
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