Sökning: onr:"swepub:oai:DiVA.org:uu-72730" > Revascularization o...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 03668naa a2200817 4500 | |
001 | oai:DiVA.org:uu-72730 | |
003 | SwePub | |
008 | 050527s2005 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-727302 URI |
024 | 7 | a https://doi.org/10.1172/JCI191892 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Li, Xuri4 aut |
245 | 1 0 | a Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors |
264 | 1 | c 2005 |
338 | a print2 rdacarrier | |
520 | a The angiogenic mechanism and therapeutic potential of PDGF-CC, a recently discovered member of the VEGF/PDGF superfamily, remain incompletely characterized. Here we report that PDGF-CC mobilized endothelial progenitor cells in ischemic conditions; induced differentiation of bone marrow cells into ECs; and stimulated migration of ECs. Furthermore, PDGF-CC induced the differentiation of bone marrow cells into smooth muscle cells and stimulated their growth during vessel sprouting. Moreover, delivery of PDGF-CC enhanced postischemic revascularization of the heart and limb. Modulating the activity of PDGF-CC may provide novel opportunities for treating ischemic diseases. | |
653 | a Animals | |
653 | a Cell Differentiation/drug effects | |
653 | a Cell Movement/drug effects | |
653 | a Cells; Cultured | |
653 | a Coronary Vessels/cytology/drug effects | |
653 | a Endothelial Cells/*cytology/*drug effects | |
653 | a Hindlimb/blood supply/drug effects | |
653 | a Humans | |
653 | a Ischemia/chemically induced/*drug therapy/metabolism/*pathology | |
653 | a Mice | |
653 | a Microcirculation/drug effects | |
653 | a Myocardium/metabolism/pathology | |
653 | a Neovascularization; Physiologic/*drug effects | |
653 | a Phosphotyrosine/metabolism | |
653 | a Platelet-Derived Growth Factor/*pharmacology | |
653 | a Receptors; Platelet-Derived Growth Factor/metabolism | |
653 | a Research Support; Non-U.S. Gov't | |
653 | a Signal Transduction | |
653 | a Stem Cells/cytology/*drug effects | |
653 | a MEDICINE | |
653 | a MEDICIN | |
700 | 1 | a Tjwa, Marc4 aut |
700 | 1 | a Moons, Lieve4 aut |
700 | 1 | a Fons, Pierre4 aut |
700 | 1 | a Noel, Agnes4 aut |
700 | 1 | a Ny, Annelii4 aut |
700 | 1 | a Zhou, Jian Min4 aut |
700 | 1 | a Lennartsson, Johanu Uppsala universitet,Ludwiginstitutet för cancerforskning4 aut0 (Swepub:uu)johalenn |
700 | 1 | a Li, Hong4 aut |
700 | 1 | a Luttun, Aernout4 aut |
700 | 1 | a Pontén, Annica4 aut |
700 | 1 | a Devy, Laetitia4 aut |
700 | 1 | a Bouché, Ann4 aut |
700 | 1 | a Oh, Hideyasu4 aut |
700 | 1 | a Manderveld, Ann4 aut |
700 | 1 | a Blacher, Silvia4 aut |
700 | 1 | a Communi, David4 aut |
700 | 1 | a Savi, Pierre4 aut |
700 | 1 | a Bono, Françoise4 aut |
700 | 1 | a Dewerchin, Mieke4 aut |
700 | 1 | a Foidart, Jean-Michel4 aut |
700 | 1 | a Autiero, Monica4 aut |
700 | 1 | a Herbert, Jean-Marc4 aut |
700 | 1 | a Collen, D4 aut |
700 | 1 | a Heldin, Carl-Henriku Uppsala universitet,Ludwiginstitutet för cancerforskning4 aut0 (Swepub:uu)carlheld |
700 | 1 | a Eriksson, Ulf4 aut |
700 | 1 | a Carmeliet, Peter4 aut |
710 | 2 | a Uppsala universitetb Ludwiginstitutet för cancerforskning4 org |
773 | 0 | t Journal of Clinical Investigationg 115:1, s. 118-127q 115:1<118-127x 0021-9738x 1558-8238 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-72730 |
856 | 4 8 | u https://doi.org/10.1172/JCI19189 |
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
Kopiera och spara länken för att återkomma till aktuell vy