Sökning: onr:"swepub:oai:DiVA.org:uu-74416" > The genome sequence...
Fältnamn | Indikatorer | Metadata |
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000 | 07014naa a2201621 4500 | |
001 | oai:DiVA.org:uu-74416 | |
003 | SwePub | |
008 | 060622s2005 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:1949447 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-744162 URI |
024 | 7 | a https://doi.org/10.1126/science.11126312 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:19494472 URI |
040 | a (SwePub)uud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a El-Sayed, Najib M.4 aut |
245 | 1 0 | a The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. |
264 | 1 | b American Association for the Advancement of Science (AAAS),c 2005 |
338 | a print2 rdacarrier | |
520 | a Whole-genome sequencing of the protozoan pathogen Trypanosoma cruzi revealed that the diploid genome contains a predicted 22,570 proteins encoded by genes, of which 12,570 represent allelic pairs. Over 50% of the genome consists of repeated sequences, such as retrotransposons and genes for large families of surface molecules, which include trans-sialidases, mucins, gp63s, and a large novel family (>1300 copies) of mucin-associated surface protein (MASP) genes. Analyses of the T. cruzi, T. brucei, and Leishmania major (Tritryp) genomes imply differences from other eukaryotes in DNA repair and initiation of replication and reflect their unusual mitochondrial DNA. Although the Tritryp lack several classes of signaling molecules, their kinomes contain a large and diverse set of protein kinases and phosphatases; their size and diversity imply previously unknown interactions and regulatory processes, which may be targets for intervention. | |
650 | 7 | a NATURVETENSKAPx Biologix Genetik0 (SwePub)106092 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Genetics0 (SwePub)106092 hsv//eng |
653 | a Animals | |
653 | a Chagas Disease/drug therapy/parasitology | |
653 | a DNA Repair | |
653 | a DNA Replication | |
653 | a DNA; Mitochondrial/genetics | |
653 | a DNA; Protozoan/genetics | |
653 | a Genes; Protozoan | |
653 | a Genome; Protozoan | |
653 | a Humans | |
653 | a Meiosis | |
653 | a Membrane Proteins/chemistry/genetics/physiology | |
653 | a Multigene Family | |
653 | a Protozoan Proteins/chemistry/*genetics/physiology | |
653 | a Recombination; Genetic | |
653 | a Repetitive Sequences; Nucleic Acid | |
653 | a Research Support; N.I.H.; Extramural | |
653 | a Research Support; Non-U.S. Gov't | |
653 | a Research Support; U.S. Gov't; P.H.S. | |
653 | a Retroelements | |
653 | a Sequence Analysis; DNA | |
653 | a Signal Transduction | |
653 | a Telomere/genetics | |
653 | a Trypanocidal Agents/pharmacology/therapeutic use | |
653 | a Trypanosoma cruzi/chemistry/*genetics/physiology | |
653 | a Genetics | |
653 | a Genetik | |
700 | 1 | a Myler, Peter J4 aut |
700 | 1 | a Bartholomeu, Daniella C4 aut |
700 | 1 | a Nilsson, Danielu Karolinska Institutet4 aut |
700 | 1 | a Aggarwal, Gautam4 aut |
700 | 1 | a Tran, Anh-Nhiu Karolinska Institutet4 aut |
700 | 1 | a Ghedin, Elodie4 aut |
700 | 1 | a Worthey, Elizabeth A4 aut |
700 | 1 | a Delcher, Arthur L4 aut |
700 | 1 | a Blandin, Gaêlle4 aut |
700 | 1 | a Westenberger, Scott J4 aut |
700 | 1 | a Caler, Elisabet4 aut |
700 | 1 | a Cerqueira, Gustavo C4 aut |
700 | 1 | a Branche, Carole4 aut |
700 | 1 | a Haas, Brian4 aut |
700 | 1 | a Anupama, Atashi4 aut |
700 | 1 | a Arner, Erik4 aut |
700 | 1 | a Aslund, Lenau Uppsala universitet,Institutionen för genetik och patologi4 aut0 (Swepub:uu)lenaaslu |
700 | 1 | a Attipoe, Philip4 aut |
700 | 1 | a Bontempi, Esteban4 aut |
700 | 1 | a Bringaud, Frederic4 aut |
700 | 1 | a Burton, Peter4 aut |
700 | 1 | a Cadag, Eithon4 aut |
700 | 1 | a Campbell, David A4 aut |
700 | 1 | a Carrington, Mark4 aut |
700 | 1 | a Crabtree, Jonathan4 aut |
700 | 1 | a Darban, Hamid4 aut |
700 | 1 | a da Silveira, Jose Franco4 aut |
700 | 1 | a de Jong, Pieter4 aut |
700 | 1 | a Edwards, Kimberly4 aut |
700 | 1 | a Englund, Paul T4 aut |
700 | 1 | a Fazelina, Gholam4 aut |
700 | 1 | a Feldblyum, Tamara4 aut |
700 | 1 | a Ferella, Marcelau Karolinska Institutet4 aut |
700 | 1 | a Frasch, Alberto Carlos4 aut |
700 | 1 | a Gull, Keith4 aut |
700 | 1 | a Horn, David4 aut |
700 | 1 | a Hou, Lihua4 aut |
700 | 1 | a Huang, Yiting4 aut |
700 | 1 | a Kindlund, Ellenu Karolinska Institutet4 aut |
700 | 1 | a Klingbeil, Michele4 aut |
700 | 1 | a Kluge, Sindy4 aut |
700 | 1 | a Koo, Hean4 aut |
700 | 1 | a Lacerda, Daniela4 aut |
700 | 1 | a Levin, Mariano J4 aut |
700 | 1 | a Lorenzi, Hernan4 aut |
700 | 1 | a Louie, Tin4 aut |
700 | 1 | a Machado, Carlos Renato4 aut |
700 | 1 | a McCulloch, Richard4 aut |
700 | 1 | a McKenna, Alan4 aut |
700 | 1 | a Mizuno, Yumi4 aut |
700 | 1 | a Mottram, Jeremy C4 aut |
700 | 1 | a Nelson, Siri4 aut |
700 | 1 | a Ochaya, Stephenu Karolinska Institutet4 aut |
700 | 1 | a Osoegawa, Kazutoyo4 aut |
700 | 1 | a Pai, Grace4 aut |
700 | 1 | a Parsons, Marilyn4 aut |
700 | 1 | a Pentony, Martin4 aut |
700 | 1 | a Pettersson, Ulfu Uppsala universitet,Institutionen för genetik och patologi4 aut0 (Swepub:uu)ulfpette |
700 | 1 | a Pop, Mihai4 aut |
700 | 1 | a Ramirez, Jose Luis4 aut |
700 | 1 | a Rinta, Joel4 aut |
700 | 1 | a Robertson, Laura4 aut |
700 | 1 | a Salzberg, Steven L4 aut |
700 | 1 | a Sanchez, Daniel O4 aut |
700 | 1 | a Seyler, Amber4 aut |
700 | 1 | a Sharma, Reuben4 aut |
700 | 1 | a Shetty, Jyoti4 aut |
700 | 1 | a Simpson, Anjana J4 aut |
700 | 1 | a Sisk, Ellen4 aut |
700 | 1 | a Tammi, Martti Tu Karolinska Institutet4 aut |
700 | 1 | a Tarleton, Rick4 aut |
700 | 1 | a Teixeira, Santuza4 aut |
700 | 1 | a Van Aken, Susan4 aut |
700 | 1 | a Vogt, Christy4 aut |
700 | 1 | a Ward, Pauline N4 aut |
700 | 1 | a Wickstead, Bill4 aut |
700 | 1 | a Wortman, Jennifer4 aut |
700 | 1 | a White, Owen4 aut |
700 | 1 | a Fraser, Claire M4 aut |
700 | 1 | a Stuart, Kenneth D4 aut |
700 | 1 | a Andersson, Björnu Karolinska Institutet4 aut |
710 | 2 | a Karolinska Institutetb Institutionen för genetik och patologi4 org |
773 | 0 | t Scienced : American Association for the Advancement of Science (AAAS)g 309:5733, s. 409-15q 309:5733<409-15x 1095-9203x 0036-8075 |
856 | 4 | u http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=16020725&dopt=Citation |
856 | 4 | u http://sgc.anlis.gob.ar/bitstream/123456789/381/1/Science%2c2005%2c309%285733%29%2c409-415..pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-74416 |
856 | 4 8 | u https://doi.org/10.1126/science.1112631 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:1949447 |
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