Sökning: onr:"swepub:oai:DiVA.org:uu-76846" > Risks of solid canc...
Fältnamn | Indikatorer | Metadata |
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000 | 06023naa a2200805 4500 | |
001 | oai:DiVA.org:uu-76846 | |
003 | SwePub | |
008 | 060627s2005 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:umu-13363 | |
009 | oai:lup.lub.lu.se:654a9037-d7fe-4a9f-ad75-a2d2c4624dc9 | |
009 | oai:prod.swepub.kib.ki.se:1938210 | |
009 | oai:DiVA.org:liu-33259 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-768462 URI |
024 | 7 | a https://doi.org/10.1136/ard.2004.0339932 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-133632 URI |
024 | 7 | a https://lup.lub.lu.se/record/2246812 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:19382102 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-332592 URI |
040 | a (SwePub)uud (SwePub)umud (SwePub)lud (SwePub)kid (SwePub)liu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Askling, Ju Karolinska Institutet4 aut |
245 | 1 0 | a Risks of solid cancers in patients with rheumatoid arthritis and after treatment with tumour necrosis factor antagonists |
264 | 1 | b BMJ,c 2005 |
338 | a print2 rdacarrier | |
520 | a BACKGROUND:Existing studies of solid cancers in rheumatoid arthritis (RA) reflect cancer morbidity up until the early 1990s in prevalent cohorts admitted to hospital during the 1980s.OBJECTIVE:To depict the cancer pattern of contemporary patients with RA, from updated risk data from prevalent and incident RA populations. To understand the risk of solid cancer after tumour necrosis factor (TNF) treatment by obtaining cancer data from cohorts treated in routine care rather than trials.METHODS:A population based study of three RA cohorts (one prevalent, admitted to hospital 1990-2003 (n = 53,067), one incident, diagnosed 1995-2003 (n = 3703), and one treated with TNF antagonists 1999-2003 (n = 4160)), which were linked with Swedish nationwide cancer and census registers and followed up for cancer occurrence through 2003.RESULTS:With 3379 observed cancers, the prevalent RA cohort was at marginally increased overall risk of solid cancer, with 20-50% increased risks for smoke related cancers and +70% increased risk for non-melanoma skin cancer, but decreased risk for breast (-20%) and colorectal cancer (-25%). With 138 cancers, the incident RA cohort displayed a similar cancer pattern apart from non-decreased risks for colorectal cancer. TNF antagonist treated patients displayed solid cancer (n = 67) risks largely similar to those of other patients with RA.CONCLUSION:The cancer pattern in patients treated with TNF antagonists mirrors those of other contemporary as well as historic RA cohorts. The consistent increase in smoking associated cancers in patients with RA emphasises the potential for smoking cessation as a cancer preventive measure in RA. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reumatologi och inflammation0 (SwePub)302102 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Rheumatology and Autoimmunity0 (SwePub)302102 hsv//eng |
653 | a Adolescent | |
653 | a Adult | |
653 | a Aged | |
653 | a Antirheumatic Agents/*adverse effects/therapeutic use | |
653 | a Arthritis; Rheumatoid/*drug therapy/epidemiology | |
653 | a Biological Response Modifiers/*adverse effects/therapeutic use | |
653 | a Epidemiologic Methods | |
653 | a Female | |
653 | a Humans | |
653 | a Male | |
653 | a Middle Aged | |
653 | a Neoplasms/*chemically induced/epidemiology | |
653 | a Research Support; Non-U.S. Gov't | |
653 | a Sweden/epidemiology | |
653 | a Tumor Necrosis Factor-alpha/*antagonists & inhibitors | |
653 | a MEDICINE | |
700 | 1 | a Fored, C Mu Karolinska Institutet4 aut |
700 | 1 | a Brandt, Lu Karolinska Institutet4 aut |
700 | 1 | a Baecklund, Evau Uppsala universitet,Reumatologi4 aut0 (Swepub:uu)evaba786 |
700 | 1 | a Bertilsson, L4 aut |
700 | 1 | a Feltelius, Nu Medical Products Agency, Uppsala, Sweden4 aut0 (Swepub:uu)nifel021 |
700 | 1 | a Cöster, Lars,d 1945-u Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Reumatologi,Länskliniken för Reumatologi i Östergötland4 aut0 (Swepub:liu)larco79 |
700 | 1 | a Geborek, Pierreu Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)reum-pge |
700 | 1 | a Jacobsson, L T4 aut |
700 | 1 | a Lindblad, Su Karolinska Institutet4 aut |
700 | 1 | a Lysholm, J4 aut |
700 | 1 | a Rantapää-Dahlqvist, Su Umeå universitet,Reumatologi4 aut0 (Swepub:umu)sora0001 |
700 | 1 | a Saxne, Toreu Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)reum-tsa |
700 | 1 | a Klareskog, Lu Karolinska Institutet4 aut |
710 | 2 | a Karolinska Institutetb Reumatologi4 org |
773 | 0 | t Annals of the Rheumatic Diseasesd : BMJg 64:10, s. 1421-1426q 64:10<1421-1426x 0003-4967x 1468-2060 |
856 | 4 | u http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=15829572&dopt=Citation |
856 | 4 | u https://ard.bmj.com/content/64/10/1421.full.pdf |
856 | 4 | u http://dx.doi.org/10.1136/ard.2004.033993x freey FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-76846 |
856 | 4 8 | u https://doi.org/10.1136/ard.2004.033993 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-13363 |
856 | 4 8 | u https://lup.lub.lu.se/record/224681 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:1938210 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-33259 |
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