Infektioner och behandling vid kroniska bensår : Antibiotikaförbrukningen alltför hög, restriktivitet förordas

• Chronic venous leg ulcers are contaminated or colonised with bacteria that seldom affects ulcer healing. Signs of clinical infection appear in only a minority of chronic ulcers. In spite of this, data show a high consumption of antibiotics in this group of patients. Treatment with antibiotics is indicated only when clinical signs of infection or obvious risk factors are present or when Streptococcus pyogenes is isolated from the ulcer. In these cases an oral antistaphylococcal agent (semisynthetic penicillinase-resistant penicillin or first generation oral cephalosporin) is recommended as the first choice. Enterococci, anaerobic bacteria and gram-negative bacteria including pseudomonas spp. often colonise chronic ulcers, but do not usually cause antibiotic requiring infection.

Nyckelord

Anti-Bacterial Agents/*administration & dosage

Chronic Disease

Drug Utilization

English Abstract

Guidelines

Humans

Prescriptions; Drug

Varicose Ulcer/*drug therapy/microbiology/pathology

Wound Healing

Wound Infection/*drug therapy/microbiology/pathology

MEDICINE

MEDICIN

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)