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Antioxidant intake,...
Antioxidant intake, oxidative stress and inflammation among immigrant women from the Middle East living in Sweden : associations with cardiovascular risk factors
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- Daryani, Achraf (författare)
- Uppsala universitet,Institutionen för folkhälso- och vårdvetenskap,Institutionen för hushållsvetenskap (IHV)
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- Basu, Samar (författare)
- Uppsala universitet,Institutionen för folkhälso- och vårdvetenskap
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Becker, Wulf (författare)
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- Larsson, Anders (författare)
- Uppsala universitet,Klinisk kemi
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- Risérus, Ulf (författare)
- Uppsala universitet,Institutionen för folkhälso- och vårdvetenskap
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(creator_code:org_t)
- Elsevier BV, 2007
- 2007
- Engelska.
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Ingår i: NMCD. Nutrition Metabolism and Cardiovascular Diseases. - : Elsevier BV. - 0939-4753 .- 1590-3729. ; 17:10, s. 748-756
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background and aims: Immigrant women from the Middle East have higher cardiovascular risk compared to native women. Whether low antioxidant intake, oxidative stress or inflammation contributes to risk is unknown. In a cross-sectional study of 157 randomly selected foreign-born women (Iranian and Turkish) and native women living in Sweden, we investigated antioxidant status, oxidative stress (F-2-isoprostanes) and systemic inflammation (plasma high sensitive C-reactive protein; CRP) markers. We also investigated relationships between F2-isoprostanes, CRP and cardiovascular risk factors. Methods and result: Dietary intake was assessed using 24-h dietary recalls repeated four times. Micronutrient intake was not consistently different between groups. Serum a-tocopherol, but not gamma-tocopherot levels, was tower in Turkish vs. Swedish women (P < 0.05). Turkish women had the highest F-2-isoprostane levels (P < 0.05 vs. Iranian women) and CRP levels (P < 0.01 vs. Swedish women and P = 0.05 vs. Iranian women). In immigrants (n = 97), F-2-isoprostanes correlated positively to insulin levels (r = 0.31, P < 0.01), and CRP was correlated to obesity and several cardiovascular risk factors (r-values >0.21, P values <0.05). Conclusion: The rote of antioxidant status is unclear, whereas signs of oxidative stress and inflammation are evident in immigrant women from Middle East, especially Turkish women. Oxidative stress and low-grade inflammation might contribute to the higher cardiovascular risk previously observed in immigrant women. Further larger studies adjusting for more potential confounders are motivated to confirm these results.
Nyckelord
- antioxidant intake
- oxidative stress
- inflammation
- C-reactive protein
- isoprostanes
- cardiovascular risk factors
- immigrants
- middle east
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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