Beyond Neuropsychiatric Diagnotics: Symptoms not Disorders

• Beyond Neuropsychiatric Diagnosis: Symptoms Not Disorders” was fertilized, confined, nourished and delivered on the 17th October (2007) with a particular type of neurodevelopmental maturity on the 21st October 2007: in gestation, an elephant, in life-span, a butterfly, in retrospect, a minor paradigm. Here, the different symptom-profiles that partially characterise putatively-shared and/or differentiating aspects of the disease process were compared, ‘staged’, highlighted, described and examined from clinical, non-clinical and basic experimental perspectives. The primary ambition and expected scope of the Meeting was to overcome the rigidly-corseting carapace of existing diagnostic classifications of mental disorders to pave opportunities for overturning current prevailing notions, to some extent pre-empting the coming of the new Diagnostic and Statistical Manual, DSM-V. As the secondary and tertiary ambitions were unfolded and prevailed, structural/functional expressions of disease states, biomarkers, neurodevelopmental liabilities, genetic polymorphisms, neurotranscription factors, molecular cascades inherent to the electrochemical processes initiated by first, second and succeeding messengers were paraded in connection with schizophrenic, depressive, abuse, cognitive, personality, affective, impulsive and comorbid disorders. Thus, common neurocircuits underlying common symptoms in psychiatric disorders, psychoses, cognition-related symptoms, motor symptoms of neuropsychiatric symptoms, impulsiveness and anhedonia, and affect were described, discussed, and dissected, accompanied by the state-of-the-art barrage of methodological stringence and innovation, conceptual finesse and in excruciatingly provocative demonstrations of neurotechnological complexity. Gradually, the shifting images of labyrinthine diagnostic veniality were overcome by those adaptive beacons of symptom-profile veracity, analytic signs and biomarkers, gene-environment predispositions and precipitating agents – harbingers of disease, not at all credo quia absurdum - were unravelled.

Ämnesord

SAMHÄLLSVETENSKAP  -- Psykologi (hsv//swe)

SOCIAL SCIENCES  -- Psychology (hsv//eng)

Nyckelord

neuropsychiatry – symptoms – diagnosis – schizophrenia – affect – epigenetics.

Publikations- och innehållstyp

vet (ämneskategori)

kap (ämneskategori)