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Predicting prolifer...
Predicting proliferative retinopathy in a Brazilian population of preterm infants with the screening algorithm WINROP
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- Hård, Anna-Lena, 1949 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation
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- Löfqvist, Chatarina, 1964 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation
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Fortes Filho, J. B. (författare)
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Procianoy, R. S. (författare)
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Smith, L. (författare)
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- Hellström, Ann, 1959 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation
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(creator_code:org_t)
- American Medical Association (AMA), 2010
- 2010
- Engelska.
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Ingår i: Archives of Ophthalmology. - : American Medical Association (AMA). - 0003-9950. ; 128:11, s. 1432-1436
- Relaterad länk:
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https://jamanetwork....
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- OBJECTIVE: To retrospectively validate the WINROP (weight, insulinlike growth factor I, neonatal, retinopathy of prematurity [ROP]) algorithm in a Brazilian population. WINROP aims to predict ROP and is based on longitudinal weight measurements from birth until postmenstrual age 36 weeks. WINROP has predicted 100% of severe ROP in 3 neonatal intensive care unit settings in the United States and Sweden. METHODS: In children admitted to the neonatal intensive care unit at Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil, from April 2002 to October 2008, weight measurements had been recorded once a week for children screened for ROP, 366 of whom had a gestational age of 32 weeks or less. The participating children had a median gestational age of 30 weeks (range, 24-32 weeks) at birth and their median birth weight was 1215 g (range, 505-2000 g). RESULTS: For 192 of 366 children (53%), no alarm or low-risk alarm after postmenstrual age 32 weeks occurred. Of these, 190 of 192 did not develop proliferative disease. Two boys with severe sepsis who were treated for ROP received low-risk alarms at postmenstrual age 33 and 34 weeks, respectively. The remaining 174 children (47%) received high- or low-risk alarms before or at 32 weeks. Of these infants, 21 (12%) developed proliferative ROP. CONCLUSIONS: In this Brazilian population, WINROP, with limited information on specific gestational age and date of weight measurement, detected early 90.5% of infants who developed stage 3 ROP and correctly predicted the majority who did not. Adjustments to the algorithm for specific neonatal intensive care unit populations may improve the results for specific preterm populations.
Nyckelord
- *Algorithms
- Birth Weight/*physiology
- Brazil
- *Developing Countries
- *Diagnostic Techniques
- Ophthalmological
- False Positive Reactions
- Female
- Gestational Age
- Humans
- Incidence
- Infant
- Infant
- Newborn
- Insulin-Like Growth Factor I/metabolism
- Intensive Care Units
- Neonatal
- Male
- Neonatal Screening/*methods
- Predictive Value of Tests
- Retinopathy of Prematurity/classification/*diagnosis
- Retrospective Studies
- Sensitivity and Specificity
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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