Altered levels of fecal chromogranins and secretogranins in IBS: relevance for pathophysiology and symptoms?

• Chromogranins (Cg) and secretogranins (Sg) are proteins ubiquitous in secretory cells of the enteric, endocrine, and immune systems, and may reflect activity of these systems. We therefore performed a hypothesis generating study to evaluate the association between fecal levels of CgA, CgB, SgII, and SgIII, with the clinical and pathophysiological phenotype of irritable bowel syndrome (IBS) patients.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Mikrobiologi inom det medicinska området (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Microbiology in the medical area (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Gastroenterologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)

Nyckelord

Adult

Aged

Biological Markers

metabolism

Chromogranins

metabolism

Feces

chemistry

Female

Gastrointestinal Transit

Humans

Irritable Bowel Syndrome

metabolism

physiopathology

Leukocyte L1 Antigen Complex

metabolism

Male

Middle Aged

Phenotype

Questionnaires

ROC Curve

Severity of Illness Index

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)