Muscle sympathetic response to arousal predicts neurovascular reactivity during mental stress

• Key points Mental stress (MS) is often initiated by a sensory or cognitive stimulus, which induces a brief arousal reaction followed by a longer stress phase. Both phases induce blood pressure (BP) increases whereas effects on muscle sympathetic nerve activity (MSNA) vary: in approximately 50% of healthy subjects (responders) arousal induces a brief MSNA reduction, which is absent in the remaining 50% (non-responders). We now report a link between the arousal response and neurovascular effects of MS in healthy males. Our data show that during MS, responders to arousal exhibited a significant decrease of MSNA and a lesser BP increase compared to non-responders. The whole material displayed a positive correlation between MSNA responses induced by arousal and MS. In addition, arousal induced MSNA changes correlated positively with BP changes during MS. We conclude that the MSNA response to arousal predicts MSNA and BP responses to MS.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

Nyckelord

future blood-pressure

acute emotional stress

nerve activity

cold

pressor

cardiovascular-responses

essential-hypertension

healthy-subjects

follow-up

humans

inhibition

rsyth rp

1972

federation proceedings

v31

p1240

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)