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Influence of Birth ...
Influence of Birth Weight on Calcaneal Bone Stiffness in Belgian Preadolescent Children
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- den Bussche, K. (författare)
- Univ Ghent, Dept Publ Hlth, B-9000 Ghent, Belgium
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- Michels, N. (författare)
- Univ Ghent, Dept Publ Hlth, B-9000 Ghent, Belgium
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- Gracia-Marco, L. (författare)
- Univ Zaragoza, Res Grp, E-50009 Zaragoza, Spain / Univ Exeter, Sch Sport & Hlth Sci, Exeter EX1 2LU, Devon, England
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- Herrmann, D. (författare)
- BIPS Inst Epidemiol & Prevent Res, D-28359 Bremen, Germany
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- Eiben, Gabriele, 1960 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine,Univ Gothenburg, Dept Pediat, Inst Clin Sci, Queen Silvia Childrens Hosp,Sahlgrenska Acad, S-41685 Gothenburg, Sweden
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- De Henauw, S. (författare)
- Univ Ghent, Dept Publ Hlth, B-9000 Ghent, Belgium / Univ Coll Ghent, Dept Hlth Sci, B-9000 Ghent, Belgium
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- Sioen, I. (författare)
- Univ Ghent, Dept Publ Hlth, B-9000 Ghent, Belgium / Res Fdn Flanders, FWO, B-1000 Brussels, Belgium
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(creator_code:org_t)
- 2012-08-22
- 2012
- Engelska.
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Ingår i: Calcified Tissue International. - : Springer Science and Business Media LLC. - 0171-967X .- 1432-0827. ; 91:4, s. 267-275
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- The aim of this study was to investigate the relation between birth weight and calcaneal bone stiffness in a large sample of Belgian, healthy, preadolescent children. Participants were 827 children (3.6-11.2 years, 51.6 % boys) from the Belgian cohort of the IDEFICS study. Birth weight was obtained using a parental questionnaire, and quantitative ultrasound (QUS) measurements were performed to determine calcaneal broadband ultrasound attenuation (BUA), speed of sound (SOS), and stiffness index (SI) using the Lunar Achilles device. Average birth weights were 3435.7 +/- A 512.0 g for boys and 3256.9 +/- A 471.1 g for girls. Average calcaneal QUS measurements were 89.6 +/- A 24.0 (23.3-153.9) dB/MHz for BUA, 1621.4 +/- A 49.6 (1516.3-1776.5) m/s for SOS, and 92.8 +/- A 15.6 (49.0-163.0) for SI. Birth weight was positively associated with BUA (r = 0.13, p = 0.002) and SOS (r = -0.16, p < 0.001). The associations remained after correcting for age and sex in multiple regression analyses but disappeared after correcting for anthropometric covariates. Our findings suggest that birth weight, as a rough proxy indicator for genetic and environmental influences during intrauterine life, is associated with BUA and SOS in preadolescent children and may therefore influence the risk of osteoporosis later in life. Further studies using QUS are needed to investigate the consistency of the results of this study.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- Birth weight
- Children
- Calcaneal quantitative ultrasound
- Bone stiffness
- south-african children
- body-mass index
- quantitative ultrasound
- early-life
- hertfordshire cohort
- growth
- osteoporosis
- childhood
- idefics
- recommendations
- Birth weight
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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