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A 5-year prospectiv...
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Bertilsson, LGothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Medicine, Department of Rheumatology and Inflammation Research,Department of Rheumatology and Inflammation Research, University of Gothenburg, Sweden
(författare)
A 5-year prospective population-based study of juvenile chronic arthritis: onset, disease process, and outcome.
- Artikel/kapitelEngelska2012
Förlag, utgivningsår, omfång ...
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2012-05-29
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Informa UK Limited,2012
Nummerbeteckningar
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LIBRIS-ID:oai:gup.ub.gu.se/165205
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https://gup.ub.gu.se/publication/165205URI
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https://doi.org/10.3109/03009742.2012.677472DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-111338URI
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https://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-19963URI
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Ämneskategori:art swepub-publicationtype
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Objectives: To investigate, in a population-based cohort of patients with juvenile chronic arthritis (JCA), onset characteristics, progression, outcome, and prognostic factors longitudinally for 5 years. Methods: This cohort consisted of 132 incidence cases identified between 1984 and 1986 in southwestern Sweden followed for 5 years with annual reports of subgroup, joint assessment, disease activity, eye examinations, laboratory measurements, and medication. At the 5-year follow-up, the Childhood Health Assessment Questionnaire (Child-HAQ) was evaluated. European League Against Rheumatism (EULAR) criteria for diagnosis and disease activity were used. Results: During the 5 years only four patients were lost to follow-up, 34% changed subgroup and 8% developed uveitis. At the 5-year follow-up the disease was active in 12% of the patients, stable in 28%, inactive in 25%, and in remission in 34%. Among those examined, 24% had radiological changes, of whom half had advanced changes. The Child-HAQ median score at the 5-year follow-up was 0.13 (range 0.0-1.9). The number of involved joints at inclusion correlated positively with active disease at the 5-year follow-up. Age at disease onset, the number of involved joints, and the number of joints with arthritis correlated positively with continuous disease and Child-HAQ score. Conclusion. Our study shows a diverse disease course during the first 5 years of JCA where one-third changed subgroup and two-thirds did not reach remission. Age of disease onset, the number of involved joints, and the number of joints with arthritis at inclusion were associated with poor outcome at the 5-year follow-up.
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Andersson-Gäre, BoelJönköping University,HHJ. Kvalitetsförbättring och ledarskap inom hälsa och välfärd,The Jönköping Academy for Improvement of Health and Welfare(Swepub:hj)andboe
(författare)
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Fasth, Anders,1945Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics,Department of Paediatrics, University of Gothenburg, Sweden(Swepub:gu)xfasan
(författare)
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Forsblad d'Elia, Helena,1961Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Medicine, Department of Rheumatology and Inflammation Research,Department of Rheumatology and Inflammation Research, University of Gothenburg, Sweden(Swepub:umu)hefo0034
(författare)
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Göteborgs universitetInstitutionen för medicin, avdelningen för reumatologi och inflammationsforskning
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Scandinavian journal of rheumatology: Informa UK Limited41:5, s. 379-821502-77320300-9742
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