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Sökning: onr:"swepub:oai:gup.ub.gu.se/177018" > Dermoscopic Evaluat...

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FältnamnIndikatorerMetadata
00005649naa a2200865 4500
001oai:gup.ub.gu.se/177018
003SwePub
008240910s2013 | |||||||||||000 ||eng|
0247 a https://gup.ub.gu.se/publication/1770182 URI
0247 a https://doi.org/10.1001/jamadermatol.2013.24662 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Menzies, Scott W4 aut
2451 0a Dermoscopic Evaluation of Nodular Melanoma.
264 1b American Medical Association (AMA),c 2013
520 a IMPORTANCE Nodular melanoma (NM) is a rapidly progressing potentially lethal skin tumor for which early diagnosis is critical. OBJECTIVE To determine the dermoscopy features of NM. DESIGN Eighty-three cases of NM, 134 of invasive non-NM, 115 of nodular benign melanocytic tumors, and 135 of nodular nonmelanocytic tumors were scored for dermoscopy features using modified and previously described methods. Lesions were separated into amelanotic/hypomelanotic or pigmented to assess outcomes. SETTING Predominantly hospital-based clinics from 5 continents. MAIN OUTCOME MEASURES Sensitivity, specificity, and odds ratios for features/models for the diagnosis of melanoma. RESULTS Nodular melanoma occurred more frequently as amelanotic/hypomelanotic (37.3%) than did invasive non-NM (7.5%). Pigmented NM had a more frequent (compared with invasive non-NM; in descending order of odds ratio) symmetrical pigmentation pattern (5.8% vs 0.8%), large-diameter vessels, areas of homogeneous blue pigmentation, symmetrical shape, predominant peripheral vessels, blue-white veil, pink color, black color, and milky red/pink areas. Pigmented NM less frequently displayed an atypical broadened network, pigment network or pseudonetwork, multiple blue-gray dots, scarlike depigmentation, irregularly distributed and sized brown dots and globules, tan color, irregularly shaped depigmentation, and irregularly distributed and sized dots and globules of any color. The most important positive correlating features of pigmented NM vs nodular nonmelanoma were peripheral black dots/globules, multiple brown dots, irregular black dots/globules, blue-white veil, homogeneous blue pigmentation, 5 to 6 colors, and black color. A model to classify a lesion as melanocytic gave a high sensitivity (>98.0%) for both nodular pigmented and nonnodular pigmented melanoma but a lower sensitivity for amelanotic/hypomelanotic NM (84%). A method for diagnosing amelanotic/hypomelanotic malignant lesions (including basal cell carcinoma) gave a 93% sensitivity and 70% specificity for NM. CONCLUSIONS AND RELEVANCE When a progressively growing, symmetrically patterned melanocytic nodule is identified, NM needs to be excluded.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Dermatologi och venereologi0 (SwePub)302042 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Dermatology and Venereal Diseases0 (SwePub)302042 hsv//eng
7001 a Moloney, Fergal J4 aut
7001 a Byth, Karen4 aut
7001 a Avramidis, Michelle4 aut
7001 a Argenziano, Giuseppe4 aut
7001 a Zalaudek, Iris4 aut
7001 a Braun, Ralph P4 aut
7001 a Malvehy, Josep4 aut
7001 a Puig, Susana4 aut
7001 a Rabinovitz, Harold S4 aut
7001 a Oliviero, Margaret4 aut
7001 a Cabo, Horacio4 aut
7001 a Bono, Riccardo4 aut
7001 a Pizzichetta, Maria A4 aut
7001 a Claeson, Magdalena,d 1976u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för dermatologi och venereologi,Institute of Clinical Sciences, Department of Dermatology and Venereology4 aut0 (Swepub:gu)xclaem
7001 a Gaffney, Daniel C4 aut
7001 a Soyer, H Peter4 aut
7001 a Stanganelli, Ignazio4 aut
7001 a Scolyer, Richard A4 aut
7001 a Guitera, Pascale4 aut
7001 a Kelly, John4 aut
7001 a McCurdy, Olivia4 aut
7001 a Llambrich, Alex4 aut
7001 a Marghoob, Ashfaq A4 aut
7001 a Zaballos, Pedro4 aut
7001 a Kirchesch, Herbert M4 aut
7001 a Piccolo, Domenico4 aut
7001 a Bowling, Jonathan4 aut
7001 a Thomas, Luc4 aut
7001 a Terstappen, Karin,d 19674 aut
7001 a Tanaka, Masaru4 aut
7001 a Pellacani, Giovanni4 aut
7001 a Pagnanelli, Gianluca4 aut
7001 a Ghigliotti, Giovanni4 aut
7001 a Ortega, Blanca Carlos4 aut
7001 a Crafter, Greg4 aut
7001 a Ortiz, Ana María Perusquía4 aut
7001 a Tromme, Isabelle4 aut
7001 a Karaarslan, Isil Kilinc4 aut
7001 a Ozdemir, Fezal4 aut
7001 a Tam, Anthony4 aut
7001 a Landi, Christian4 aut
7001 a Norton, Peter4 aut
7001 a Kaçar, Nida4 aut
7001 a Rudnicka, Lidia4 aut
7001 a Slowinska, Monika4 aut
7001 a Simionescu, Olga4 aut
7001 a Di Stefani, Alessandro4 aut
7001 a Coates, Elliot4 aut
7001 a Kreusch, Juergen4 aut
7102 a Göteborgs universitetb Institutionen för kliniska vetenskaper, Avdelningen för dermatologi och venereologi4 org
7730 t JAMA dermatology (Chicago, Ill.)d : American Medical Association (AMA)g 149:6, s. 699-709q 149:6<699-709x 2168-6084x 2168-6068
8564 u https://jamanetwork.com/journals/jamadermatology/articlepdf/1675049/dst120068_699_709.pdf
8564 8u https://gup.ub.gu.se/publication/177018
8564 8u https://doi.org/10.1001/jamadermatol.2013.2466

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