Sökning: onr:"swepub:oai:gup.ub.gu.se/177018" > Dermoscopic Evaluat...
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000 | 05649naa a2200865 4500 | |
001 | oai:gup.ub.gu.se/177018 | |
003 | SwePub | |
008 | 240910s2013 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/1770182 URI |
024 | 7 | a https://doi.org/10.1001/jamadermatol.2013.24662 DOI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Menzies, Scott W4 aut |
245 | 1 0 | a Dermoscopic Evaluation of Nodular Melanoma. |
264 | 1 | b American Medical Association (AMA),c 2013 |
520 | a IMPORTANCE Nodular melanoma (NM) is a rapidly progressing potentially lethal skin tumor for which early diagnosis is critical. OBJECTIVE To determine the dermoscopy features of NM. DESIGN Eighty-three cases of NM, 134 of invasive non-NM, 115 of nodular benign melanocytic tumors, and 135 of nodular nonmelanocytic tumors were scored for dermoscopy features using modified and previously described methods. Lesions were separated into amelanotic/hypomelanotic or pigmented to assess outcomes. SETTING Predominantly hospital-based clinics from 5 continents. MAIN OUTCOME MEASURES Sensitivity, specificity, and odds ratios for features/models for the diagnosis of melanoma. RESULTS Nodular melanoma occurred more frequently as amelanotic/hypomelanotic (37.3%) than did invasive non-NM (7.5%). Pigmented NM had a more frequent (compared with invasive non-NM; in descending order of odds ratio) symmetrical pigmentation pattern (5.8% vs 0.8%), large-diameter vessels, areas of homogeneous blue pigmentation, symmetrical shape, predominant peripheral vessels, blue-white veil, pink color, black color, and milky red/pink areas. Pigmented NM less frequently displayed an atypical broadened network, pigment network or pseudonetwork, multiple blue-gray dots, scarlike depigmentation, irregularly distributed and sized brown dots and globules, tan color, irregularly shaped depigmentation, and irregularly distributed and sized dots and globules of any color. The most important positive correlating features of pigmented NM vs nodular nonmelanoma were peripheral black dots/globules, multiple brown dots, irregular black dots/globules, blue-white veil, homogeneous blue pigmentation, 5 to 6 colors, and black color. A model to classify a lesion as melanocytic gave a high sensitivity (>98.0%) for both nodular pigmented and nonnodular pigmented melanoma but a lower sensitivity for amelanotic/hypomelanotic NM (84%). A method for diagnosing amelanotic/hypomelanotic malignant lesions (including basal cell carcinoma) gave a 93% sensitivity and 70% specificity for NM. CONCLUSIONS AND RELEVANCE When a progressively growing, symmetrically patterned melanocytic nodule is identified, NM needs to be excluded. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Dermatologi och venereologi0 (SwePub)302042 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Dermatology and Venereal Diseases0 (SwePub)302042 hsv//eng |
700 | 1 | a Moloney, Fergal J4 aut |
700 | 1 | a Byth, Karen4 aut |
700 | 1 | a Avramidis, Michelle4 aut |
700 | 1 | a Argenziano, Giuseppe4 aut |
700 | 1 | a Zalaudek, Iris4 aut |
700 | 1 | a Braun, Ralph P4 aut |
700 | 1 | a Malvehy, Josep4 aut |
700 | 1 | a Puig, Susana4 aut |
700 | 1 | a Rabinovitz, Harold S4 aut |
700 | 1 | a Oliviero, Margaret4 aut |
700 | 1 | a Cabo, Horacio4 aut |
700 | 1 | a Bono, Riccardo4 aut |
700 | 1 | a Pizzichetta, Maria A4 aut |
700 | 1 | a Claeson, Magdalena,d 1976u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för dermatologi och venereologi,Institute of Clinical Sciences, Department of Dermatology and Venereology4 aut0 (Swepub:gu)xclaem |
700 | 1 | a Gaffney, Daniel C4 aut |
700 | 1 | a Soyer, H Peter4 aut |
700 | 1 | a Stanganelli, Ignazio4 aut |
700 | 1 | a Scolyer, Richard A4 aut |
700 | 1 | a Guitera, Pascale4 aut |
700 | 1 | a Kelly, John4 aut |
700 | 1 | a McCurdy, Olivia4 aut |
700 | 1 | a Llambrich, Alex4 aut |
700 | 1 | a Marghoob, Ashfaq A4 aut |
700 | 1 | a Zaballos, Pedro4 aut |
700 | 1 | a Kirchesch, Herbert M4 aut |
700 | 1 | a Piccolo, Domenico4 aut |
700 | 1 | a Bowling, Jonathan4 aut |
700 | 1 | a Thomas, Luc4 aut |
700 | 1 | a Terstappen, Karin,d 19674 aut |
700 | 1 | a Tanaka, Masaru4 aut |
700 | 1 | a Pellacani, Giovanni4 aut |
700 | 1 | a Pagnanelli, Gianluca4 aut |
700 | 1 | a Ghigliotti, Giovanni4 aut |
700 | 1 | a Ortega, Blanca Carlos4 aut |
700 | 1 | a Crafter, Greg4 aut |
700 | 1 | a Ortiz, Ana María Perusquía4 aut |
700 | 1 | a Tromme, Isabelle4 aut |
700 | 1 | a Karaarslan, Isil Kilinc4 aut |
700 | 1 | a Ozdemir, Fezal4 aut |
700 | 1 | a Tam, Anthony4 aut |
700 | 1 | a Landi, Christian4 aut |
700 | 1 | a Norton, Peter4 aut |
700 | 1 | a Kaçar, Nida4 aut |
700 | 1 | a Rudnicka, Lidia4 aut |
700 | 1 | a Slowinska, Monika4 aut |
700 | 1 | a Simionescu, Olga4 aut |
700 | 1 | a Di Stefani, Alessandro4 aut |
700 | 1 | a Coates, Elliot4 aut |
700 | 1 | a Kreusch, Juergen4 aut |
710 | 2 | a Göteborgs universitetb Institutionen för kliniska vetenskaper, Avdelningen för dermatologi och venereologi4 org |
773 | 0 | t JAMA dermatology (Chicago, Ill.)d : American Medical Association (AMA)g 149:6, s. 699-709q 149:6<699-709x 2168-6084x 2168-6068 |
856 | 4 | u https://jamanetwork.com/journals/jamadermatology/articlepdf/1675049/dst120068_699_709.pdf |
856 | 4 8 | u https://gup.ub.gu.se/publication/177018 |
856 | 4 8 | u https://doi.org/10.1001/jamadermatol.2013.2466 |
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