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Effects of high-flu...
Effects of high-fluoride dentifrice (5,000-ppm) on caries-related plaque and salivary variables.
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- Mannaa, Alaa (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
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- Carlén, Anette, 1950 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
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Zaura, Egija (författare)
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Buijs, Mark J (författare)
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Bukhary, Sahar (författare)
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- Lingström, Peter, 1960 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för odontologi, sektion 3,Institute of Odontology, Section 3
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(creator_code:org_t)
- 2013-10-08
- 2014
- Engelska.
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Ingår i: Clinical Oral Investigations. - : Springer Science and Business Media LLC. - 1432-6981 .- 1436-3771. ; 18:5, s. 1419-1426
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- OBJECTIVES: The aim of the present study was to measure the effects of a 5,000-ppmF toothpaste on caries-related factors in dental plaque and saliva. MATERIALS AND METHODS: A 6-week clinical trial was designed with a total of 34 participants, of which 26 completed the study. The participants were assessed on four visits, 2 weeks apart. Sampling of approximal fluid for fluoride analysis and approximal plaque for organic acid analysis was performed. Chair-side tests were performed to register the lactic acid production rate on the tongue using Clinpro™ Cario L-Pop™, approximal plaque pH using the pH "strip method" and salivary buffer capacity and counts of cariogenic microorganisms using CRT Buffer® and CRT Bacteria®. RESULTS: Six weeks' use of 5,000-ppm fluoridated (F) toothpaste significantly increased the approximal fluid F concentration (p<0.05). There was a significant decrease in lactic acid production rate on the tongue assessed by Clinpro™ (p<0.05). This was accompanied by changes in interproximal plaque acidogenicity, including significant reductions in AUC5.7, AUC6.2 and maximum pH fall and an increase in minimum pH (p<0.05). A significant increase in the salivary buffer capacity and a reduction in the salivary mutans streptococci were observed (p<0.05). CONCLUSION: The present study demonstrates the ability of 5,000-ppm F toothpaste to modify caries-related factors in dental plaque and saliva. CLINICAL RELEVANCE: The 5,000-ppm F toothpaste could be regarded as a possible effective regimen against caries in the near future
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine (hsv//eng)
Nyckelord
- Cariogenic microorganisms; Dentifrice; Fluoride; pH; Plaque; Saliva
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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