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An enzymatic chroma...
An enzymatic chromatin switch that directs formation of active brown fat
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- Enerbäck, Sven, 1958 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk genetik och klinisk genetik,Institute of Biomedicine, Department of Medical and Clinical Genetics
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(creator_code:org_t)
- Elsevier BV, 2014
- 2014
- Engelska.
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Ingår i: Cell Metabolism. - : Elsevier BV. - 1550-4131 .- 1932-7420. ; 19:1, s. 3-4
- Relaterad länk:
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http://www.cell.com/...
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Abstract
Ämnesord
Stäng
- How is the recruitment of brown adipocytes regulated? Ohno et al. (2013) show that the euchromatic histone-lysine N-metyltransferase 1 (EHMT1) is essential for the specification of the brown adipocyte fate, a finding with important implications for the pathophysiology of obesity and obesity-related maladies. © 2014 Elsevier Inc.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Cell- och molekylärbiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Cell and Molecular Biology (hsv//eng)
Nyckelord
- cre recombinase
- early b lymphocyte factor 2
- euchromatic histonelysine n metyltransferase 1
- growth promotor
- myogenic factor 5
- peroxisome proliferator activated receptor gamma
- protein methyltransferase
- protein precursor
- unclassified drug
- brown adipose tissue
- cell differentiation
- cell fate
- cell transformation
- cold exposure
- DNA methylation
- enzymatic chromatin switch
- enzyme activity
- gene control
- glucose tolerance
- human
- long term exposure
- mitochondrial respiration
- muscle
- obesity
- priority journal
- review
- white adipose tissue
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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