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High dose versus lo...
High dose versus low dose oxytocin for augmentation of delayed labour, a randomized controlled trial
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Selin, Lotta (författare)
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- Berg, Marie, 1955 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för vårdvetenskap och hälsa,Institute of Health and Care Sciences
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Wennerholm, Ulla-Britt, 1948 (författare)
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Wallin, Gunnar, 1952 (författare)
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Almström, Elisabeth (författare)
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- Dencker, Anna, 1956 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för vårdvetenskap och hälsa,Centrum för personcentrerad vård vid Göteborgs universitet (GPCC),Institute of Health and Care Sciences,University of Gothenburg Centre for person-centred care (GPCC)
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- Petzold, Max, 1973 (författare)
- Gothenburg University,Göteborgs universitet,Akademistatistik,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för arbets-och miljömedicin,Centre for Applied Biostatistics,Institute of Medicine, Department of Public Health and Community Medicine, Section of Occupational and environmental medicine
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(creator_code:org_t)
- 2014
- 2014
- Engelska.
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Ingår i: Optimizing childbirth across Europe - an intedisciplinary maternity care conference. 9-10 April 2014, Brussels. Part of COST Action IS0907: Childbirth Cultures, Concerns & Consequences: Creating a dynamic EU framework for Optimal maternity care..
- Relaterad länk:
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https://gup.ub.gu.se...
Abstract
Ämnesord
Stäng
- Introduction: Delay in labour due to ineffective uterine contractions is a major problem in obstetric care and a main reason for the increased rate of caesarean deliveries, particularly among nulliparous women. Infusion with synthetic oxytocin is a commonly used treatment of hypotonic uterine contractions however there is a gap of knowledge concerning which dosage of oxytocin should be used, both starting dose and increment dose of oxytocin. Aim of the study: The aim is to compare starting dose and increment of amount of oxytocin for augmentation of delayed labour to determine whether augmentation by high dose of oxytocin improves labour outcomes compared with a low dose of oxytocin, without affecting neonatal or maternal outcomes including birth experiences negatively. Research methodology: In a randomized double-blind controlled trial conducted in three labour wards in Sweden, consenting nulliparous women in active labour and with a defined delayed progress are randomized to receive a regimen of either high dose or low dose of oxytocin (33.2 respectively 16,6 microgram oxytocin in 1000 ml isotone saline solution). randomization will be computer-generated, with allocation concealment by a coding system. Primary outcome is caesarean delivery rate. Based on a sample size calculation (α=0.05, β=0.80), a minimum of 688 women will be included in each group in order to reduce caesarean section rate from 17.5 % to 12 %. Ethical approval: The study is approved by the regional Ethics Board in Gothenburg (dnr: 090-12), and by the medical Products Agency –Sweden (Eudra-CTnr:2012-000356-33). Study finding: This poster will describe the study protocol and the first period of data collection. Results will concern: 1) maternal and fetal outcomes in randomized groups, and 2) maternal overall childbirth experience including labour pain. Conclusion: The study will contribute to establishment of evidencebased routines regarding oxytocin treatment of delayed labour progress.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap -- Övrig annan medicin och hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences -- Other Medical and Health Sciences not elsewhere specified (hsv//eng)
Nyckelord
- oxytocin
- delayed labour progress
Publikations- och innehållstyp
- vet (ämneskategori)
- kon (ämneskategori)
- Av författaren/redakt...
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Selin, Lotta
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Berg, Marie, 195 ...
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Wennerholm, Ulla ...
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Wallin, Gunnar, ...
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Almström, Elisab ...
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Dencker, Anna, 1 ...
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visa fler...
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Petzold, Max, 19 ...
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Annan medicin oc ...
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och Övrig annan medi ...
- Artiklar i publikationen
- Optimizing child ...
- Av lärosätet
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Göteborgs universitet