Sökning: onr:"swepub:oai:gup.ub.gu.se/203690" > The impact of eleva...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 03448naa a2200493 4500 | |
001 | oai:gup.ub.gu.se/203690 | |
003 | SwePub | |
008 | 240528s2014 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/2036902 URI |
024 | 7 | a https://doi.org/10.1016/j.dld.2014.06.0102 DOI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Benito de Valle, Mariau Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine4 aut |
245 | 1 0 | a The impact of elevated serum IgG4 levels in patients with primary sclerosing cholangitis |
264 | 1 | b Elsevier BV,c 2014 |
520 | a Background: Elevated IgG4 levels have been reported among patients with primary sclerosing cholangitis. Epidemiological data has only been provided from tertiary centres. Aims: To investigate the prevalence of elevated IgG4 levels and to compare prognosis between patients with and without elevated IgG4 levels in serum in two European cohorts of patients with primary sclerosing cholangitis. Methods: Serum IgG4-levels were measured in a consecutive series of patients from Berlin, and retrospectively collected in a population-based cohort from Sweden (total N = 345). Cox's proportional hazard analysis was used to calculate relative risks for liver-related death or liver transplantation and cholangiocarcinoma. Results: Elevated IgG4 values were demonstrated in 10% of patients. A previous history of pancreatitis, combined intra-and extrahepatic biliary involvement and jaundice were independently associated with elevated IgG4 in multivariate analysis. IgG4 status was not associated with an increased risk for the combined endpoint liver-related death or liver transplantation or cholangiocarcinoma. Conclusion: The prevalence of elevated IgG4 values among European patients with primary sclerosing cholangitis is similar to what previously has been reported from the United States. Elevated IgG4 was not associated with an increased risk of liver transplantation or liver-related death or cholangiocarcinoma. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng |
653 | a IgG4 status | |
653 | a Prevalence | |
653 | a Survival | |
653 | a IMMUNOGLOBULIN G4-ASSOCIATED CHOLANGITIS | |
653 | a THERAPY | |
653 | a SPECTRUM | |
653 | a G4 | |
653 | a Gastroenterology & Hepatology | |
700 | 1 | a Muller, T.4 aut |
700 | 1 | a Bjornsson, E.4 aut |
700 | 1 | a Otten, M.4 aut |
700 | 1 | a Volkmann, M.4 aut |
700 | 1 | a Guckelberger, O.4 aut |
700 | 1 | a Wiedenmann, B.4 aut |
700 | 1 | a Sadik, Riadh,d 1963u Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine4 aut0 (Swepub:gu)xsadri |
700 | 1 | a Schott, E.4 aut |
700 | 1 | a Andersson, M.4 aut |
700 | 1 | a Berg, T.4 aut |
700 | 1 | a Lindkvist, Björnu Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine4 aut0 (Swepub:gu)xlibjo |
710 | 2 | a Göteborgs universitetb Institutionen för medicin4 org |
773 | 0 | t Digestive and Liver Diseased : Elsevier BVg 46:10, s. 903-908q 46:10<903-908x 1590-8658 |
856 | 4 8 | u https://gup.ub.gu.se/publication/203690 |
856 | 4 8 | u https://doi.org/10.1016/j.dld.2014.06.010 |
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.