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Allergy-related dis...
Allergy-related diseases and recurrent abdominal pain during childhood - a birth cohort study
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- Olen, O. (författare)
- Karolinska Institutet
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- Neuman, Åsa (författare)
- Karolinska Institutet,Uppsala universitet,Pediatrik
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- Koopmann, B. (författare)
- Dept Med, Clin Epidemiol Unit, Karolinska Inst, Stockholm, Sweden
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- Ludvigsson, Jonas F., 1969- (författare)
- Karolinska Institutet,Region Örebro län,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Pediatrics, Örebro University Hospital, Örebro, Sweden
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- Ballardini, N. (författare)
- Karolinska Institutet
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- Westman, M. (författare)
- Karolinska Institutet
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- Melen, E. (författare)
- Karolinska Institutet
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- Kull, I. (författare)
- Karolinska Institutet
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- Simrén, Magnus, 1966 (författare)
- Gothenburg University,Göteborgs universitet,Centrum för personcentrerad vård vid Göteborgs universitet (GPCC),Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,University of Gothenburg Centre for person-centred care (GPCC),Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Dept Internal Med, Inst Med, Sahlgrenska Acad, Univ Gothenburg, Gothenburg, Sweden; Ctr Person Ctr Care, Sahlgrenska Acad, Univ Gothenburg, Gothenburg, Sweden
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- Bergstrom, A. (författare)
- Karolinska Institutet
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(creator_code:org_t)
- 2014-10-01
- 2014
- Engelska.
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Ingår i: Alimentary Pharmacology & Therapeutics. - : Wiley. - 0269-2813 .- 1365-2036. ; 40:11, s. 1349-1358
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- BackgroundAllergy and immune dysregulation may have a role in the pathophysiology of recurrent abdominal pain of functional origin, but previous studies of allergy-related diseases and abdominal pain have contradictory results. AimTo examine the association between allergy-related diseases or sensitisation during childhood and abdominal pain at age 12years. MethodsIn this birth cohort study of 4089 children, parents answered questionnaires regarding asthma, allergic rhinitis, eczema and food hypersensitivity (allergy-related diseases') at ages 0,1,2,4,8 and 12years. Blood for analyses of allergen-specific IgE was sampled at 4 and 8years. At 12years, the children answered questions regarding abdominal pain. Children with coeliac disease or inflammatory bowel disease were excluded. Associations were examined using multivariable logistic regression. ResultsAmong 2610 children with complete follow-up, 9% (n=237) reported abdominal pain at 12years. All allergy-related diseases were associated with concurrent abdominal pain at 12years and the risk increased with increasing number of allergy-related diseases (P for trend <0.001). Asthma at 1 and 2years and food hypersensitivity at 8years were significantly associated with abdominal pain at 12years. There was an increased risk of abdominal pain at 12years in children sensitised to food allergens at 4 or 8years, but in stratified analyses, this was confined to children whose parents had not reported food hypersensitivity at time of sensitisation. ConclusionAllergy-related diseases as well as sensitisation to food allergens were associated with an elevated risk of abdominal pain, and the risk increased with the number of allergy-related diseases.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)
Nyckelord
- IRRITABLE-BOWEL-SYNDROME
- FUNCTIONAL GASTROINTESTINAL DISORDERS
- QUALITY-OF-LIFE
- ASTHMA PATIENTS
- MAST-CELLS
- VISCERAL HYPERSENSITIVITY
- FOOD HYPERSENSITIVITY
- ATOPIC-DERMATITIS
- BRONCHIAL-ASTHMA
- CHILDREN
- Gastroenterology & Hepatology
- Pharmacology & Pharmacy
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Olen, O.
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Neuman, Åsa
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Koopmann, B.
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Ludvigsson, Jona ...
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Ballardini, N.
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Westman, M.
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Melen, E.
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Kull, I.
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Simrén, Magnus, ...
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Bergstrom, A.
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Gastroenterologi
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Medicinska och f ...
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och Farmakologi och ...
- Artiklar i publikationen
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Alimentary Pharm ...
- Av lärosätet
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Göteborgs universitet
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Örebro universitet
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Uppsala universitet
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Karolinska Institutet