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Physical Activity a...
Physical Activity and Survival among Men Diagnosed with Prostate Cancer
- Artikel/kapitelEngelska2015
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2015-01-13
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American Association for Cancer Research (AACR),2015
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LIBRIS-ID:oai:gup.ub.gu.se/212897
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https://gup.ub.gu.se/publication/212897URI
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https://doi.org/10.1158/1055-9965.epi-14-0707DOI
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Ämneskategori:art swepub-publicationtype
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Background: Few studies have investigated the association between post-diagnosis physical activity and mortality among men diagnosed with prostate cancer. The aim of this study was to investigate the effect of physical activity after a prostate cancer diagnosis on both overall and prostate cancer-specific mortality in a large cohort. Methods: Data from 4,623 men diagnosed with localized prostate cancer 1997-2002 and followed-up until 2012 were analyzed. HRs with 95% confidence intervals (CI) were estimated using Cox proportional hazards models to examine the association between post-diagnosis recreational MET-h/d, time spent walking/bicycling, performing household work or exercising, and time to overall and prostate cancer-specific death. All models were adjusted for potential confounders. Results: During the follow-up, 561 deaths of any cause and 194 deaths from prostate cancer occurred. Statistically significantly lower overall mortality rates were found among men engaged in 5 recreationalMET-h/d (HR, 0.63; 95% CI, 0.52-0.77), walking/ bicycling 20 min/d (HR, 0.70; 95% CI, 0.57-0.86), performing householdwork > 1 h/d (HR, 0.71; 95% CI, 0.59-0.86), or exercising > 1 h/wk (HR, 0.74; 95% CI, 0.61-0.90), compared with less active men within each activity type. For prostate cancer-specific mortality, statistically significantly lower mortality rates were seen among men walking/bicycling >= 20 min/d (HR, 0.61; 95% CI, 0.43-0.87) or exercising 1 h/wk (HR, 0.68; 95% CI, 0.48-0.94). Conclusions: Higher levels of physical activity were associated with reduced rates of overall and prostate cancer-specific mortality. Impact: Our study further strengthens previous results indicating beneficial effects of physical activity on survival among men with prostate cancer.
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Biuppslag (personer, institutioner, konferenser, titlar ...)
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Sjolander, A.
(författare)
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Lagerros, Y. T.
(författare)
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Wiklund, F.
(författare)
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Stattin, P.
(författare)
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Holmberg, Erik,1951Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för onkologi,Institute of Clinical Sciences, Department of Oncology(Swepub:gu)xholer
(författare)
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Gronberg, H.
(författare)
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Balter, K.
(författare)
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Göteborgs universitetInstitutionen för kliniska vetenskaper, Avdelningen för onkologi
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Cancer Epidemiology Biomarkers & Prevention: American Association for Cancer Research (AACR)24:1, s. 57-641055-99651538-7755
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