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Pharmacological lip...
Pharmacological lipid lowering for prevention of cardiovascular disease in older adults
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- Wiklund, Olov, 1943 (författare)
- Gothenburg University,Göteborgs universitet,Wallenberglaboratoriet,Wallenberg Laboratory
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- Pirazzi, Carlo (författare)
- Gothenburg University,Göteborgs universitet,Wallenberglaboratoriet,Wallenberg Laboratory
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- Romeo, Stefano, 1976 (författare)
- Gothenburg University,Göteborgs universitet,Wallenberglaboratoriet,Wallenberg Laboratory
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(creator_code:org_t)
- Future Medicine Ltd. 2014
- 2014
- Engelska.
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Ingår i: Clinical Practice. - : Future Medicine Ltd.. - 2044-9038 .- 2044-9046. ; 11:1, s. 49-58
- Relaterad länk:
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https://gup.ub.gu.se...
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visa fler...
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https://doi.org/10.2...
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Abstract
Ämnesord
Stäng
- An increasing number of patients with cardiovascular disease (CVD) are older adults. New treatments have improved survival but also increased demand for prevention. Comorbidities in older adults contribute to low cholesterol, but accumulating data show that dyslipidemia is a risk factor for CVD in older adults. Although numerous studies show that statin treatment reduces CVD mortality and morbidity, few studies have targeted older adults specifically. However, post-hoc analyses of subgroups indicate that older adults may benefit from statin treatment. Risk reduction in secondary prevention is similar across all age groups, and the limited data available in primary prevention suggest that statins may be considered in high-risk older adult patients. However, statin therapy in older adults should be individualized, taking into account factors more common in this group. © 2014 Future Medicine Ltd.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- antilipemic agent
- atorvastatin
- hydroxymethylglutaryl coenzyme A reductase inhibitor
- low density lipoprotein cholesterol
- mevinolin
- placebo
- pravastatin
- rosuvastatin
- simvastatin
- body weight
- cardiovascular disease
- cardiovascular mortality
- cholesterol blood level
- comorbidity
- disease association
- drug effect
- drug targeting
- dyslipidemia
- heart protection
- high risk patient
- human
- hypertransaminasemia
- kidney failure
- life expectancy
- lifestyle
- muscle disease
- muscle necrosis
- myalgia
- myoglobinuria
- myopathy
- non insulin dependent diabetes mellitus
- patient compliance
- patient preference
- primary prevention
- quality of life
- review
- rhabdomyolysis
- risk factor
- risk reduction
- secondary prevention
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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