Sökning: onr:"swepub:oai:gup.ub.gu.se/213126" > Efficient predictio...
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000 | 05551naa a2200793 4500 | |
001 | oai:gup.ub.gu.se/213126 | |
003 | SwePub | |
008 | 240910s2014 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:liu-114135 | |
024 | 7 | a https://gup.ub.gu.se/publication/2131262 URI |
024 | 7 | a https://doi.org/10.1186/s12859-014-0383-12 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1141352 URI |
040 | a (SwePub)gud (SwePub)liu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Schoenrock, A.u Carleton University, Ottawa, Canada4 aut |
245 | 1 0 | a Efficient prediction of human protein-protein interactions at a global scale |
264 | c 2014-12-10 | |
264 | 1 | b Springer Science and Business Media LLC,c 2014 |
520 | a Background: Our knowledge of global protein-protein interaction (PPI) networks in complex organisms such as humans is hindered by technical limitations of current methods. Results: On the basis of short co-occurring polypeptide regions, we developed a tool called MP-PIPE capable of predicting a global human PPI network within 3 months. With a recall of 23% at a precision of 82.1%, we predicted 172,132 putative PPIs. We demonstrate the usefulness of these predictions through a range of experiments. Conclusions: The speed and accuracy associated with MP-PIPE can make this a potential tool to study individual human PPI networks (from genomic sequences alone) for personalized medicine. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Cell- och molekylärbiologi0 (SwePub)301082 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Cell and Molecular Biology0 (SwePub)301082 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng |
653 | a Protein-protein interactions | |
653 | a Computational prediction | |
653 | a Human proteome | |
653 | a Massively parallel | |
653 | a YEAST SACCHAROMYCES-CEREVISIAE | |
653 | a SHORT POLYPEPTIDE SEQUENCES | |
653 | a INTERACTION | |
653 | a NETWORKS | |
653 | a ALLERGIC RHINITIS | |
653 | a DNA-DAMAGE | |
653 | a COMPUTATIONAL METHODS | |
653 | a MESSENGER-RNA | |
653 | a BREAST-CANCER | |
653 | a AURORA B | |
653 | a DISEASE | |
653 | a Biochemical Research Methods | |
653 | a Biotechnology & Applied Microbiology | |
653 | a Mathematical & Computational Biology | |
700 | 1 | a Samanfar, B.u Carleton University, Ottawa, Canada4 aut |
700 | 1 | a Pitre, S.u Carleton University, Ottawa, Canada4 aut |
700 | 1 | a Hooshyar, M.u Carleton University, Ottawa, Canada4 aut |
700 | 1 | a Jin, K.u University of Toronto, Toronto, Canada4 aut |
700 | 1 | a Phillips, C. A.u University of Tennessee, Knoxville, Tennessee, USA4 aut |
700 | 1 | a Wang, Huiu Linköpings universitet,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics,Avdelningen för kliniska vetenskaper,Hälsouniversitetet,Gothenburg University, Gothenburg, Sweden,The Centre for Individualized Medication4 aut0 (Swepub:liu)huiwa84 |
700 | 1 | a Phanse, S.u University of Toronto, Toronto, Canada4 aut |
700 | 1 | a Omidi, K.u University of Toronto, Toronto, Canada4 aut |
700 | 1 | a Gui, Y.u University of Toronto, Toronto, Canada4 aut |
700 | 1 | a Alamgir, M.u University of Toronto, Toronto, Canada,Carleton University, Ottawa, Canada4 aut |
700 | 1 | a Wong, A.u University of Toronto, Toronto, Canada4 aut |
700 | 1 | a Barrenäs, Fredrik,d 1981u Linköpings universitet,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics,Avdelningen för kliniska vetenskaper,Hälsouniversitetet,Gothenburg University, Gothenburg, Sweden,The Centre for Individualized Medication4 aut0 (Swepub:liu)freba19 |
700 | 1 | a Babu, M.u University of Regina, Regina, Saskatchewan, Canada4 aut |
700 | 1 | a Benson, Mikael,d 1954u Östergötlands Läns Landsting,Linköpings universitet,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics,Avdelningen för kliniska vetenskaper,Hälsouniversitetet,Allergicentrum US,Barn- och ungdomskliniken i Linköping,Gothenburg University, Gothenburg, Sweden,The Centre for Individualized Medication4 aut0 (Swepub:liu)mikbe05 |
700 | 1 | a Langston, M. A.4 aut |
700 | 1 | a Green, J. R.u Carleton University, Ottawa, Canada4 aut |
700 | 1 | a Dehne, F.u Carleton University, Ottawa, Canada4 aut |
700 | 1 | a Golshani, A.u Carleton University, Ottawa, Canada4 aut |
710 | 2 | a Carleton University, Ottawa, Canadab University of Toronto, Toronto, Canada4 org |
773 | 0 | t Bmc Bioinformaticsd : Springer Science and Business Media LLCg 15q 15x 1471-2105 |
856 | 4 | u https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/s12859-014-0383-1 |
856 | 4 | u https://liu.diva-portal.org/smash/get/diva2:787556/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 8 | u https://gup.ub.gu.se/publication/213126 |
856 | 4 8 | u https://doi.org/10.1186/s12859-014-0383-1 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-114135 |
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