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Prophylaxis and tre...
Prophylaxis and treatment of HIV-1 infection in pregnancy: Swedish recommendations 2013.
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- Navér, Lars (författare)
- Karolinska Institutet
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- Albert, Jan (författare)
- Karolinska Institutet
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- Böttiger, Ylva (författare)
- Karolinska Institutet
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- Carlander, Christina (författare)
- Karolinska Institutet
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- Flamholc, Leo (författare)
- Lund University,Lunds universitet,Enheten för infektionssjukdomar,Forskargrupper vid Lunds universitet,Infectious Diseases Research Unit,Lund University Research Groups
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- Gisslén, Magnus, 1962 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine
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Josephson, Filip (författare)
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Karlström, Olof (författare)
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Lindborg, Lena (författare)
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- Svedhem-Johansson, Veronica (författare)
- Karolinska Institutet
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Svennerholm, Bo (författare)
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- Sönnerborg, Anders (författare)
- Karolinska Institutet
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- Yilmaz, Aylin, 1974 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine
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- Pettersson, Karin (författare)
- Karolinska Institutet
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(creator_code:org_t)
- 2014-04-22
- 2014
- Engelska.
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Ingår i: Scandinavian journal of infectious diseases. - : Informa UK Limited. - 1651-1980 .- 0036-5548. ; 46:6, s. 401-11
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http://dx.doi.org/10...
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https://doi.org/10.3...
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Abstract
Ämnesord
Stäng
- Prophylaxis and treatment with antiretroviral drugs and elective caesarean section delivery have resulted in very low mother-to-child transmission of HIV during recent years. Updated general treatment guidelines and increasing knowledge about mother-to-child transmission have necessitated regular revisions of the recommendations for the prophylaxis and treatment of HIV-1 infection in pregnancy. The Swedish Reference Group for Antiviral Therapy (RAV) updated the recommendations from 2010 at an expert meeting on 11 September 2013. The most important revisions are the following: (1) ongoing efficient treatment at confirmed pregnancy may, with a few exceptions, be continued; (2) if treatment is initiated during pregnancy, the recommended first-line therapy is essentially the same as for non-pregnant women; (3) raltegravir may be added to achieve rapid reduction in HIV RNA; (4) vaginal delivery is recommended if at > 34 gestational weeks and HIV RNA is < 50 copies/ml and no obstetric contraindications exist; (5) if HIV RNA is < 50 copies/ml and delivery is at > 34 gestational weeks, intravenous zidovudine is not recommended regardless of the delivery mode; (6) if HIV RNA is > 50 copies/ml close to delivery, it is recommended that the mother should undergo a planned caesarean section, intravenous zidovudine, and oral nevirapine, and the infant should receive single-dose nevirapine at 48-72 h of age and post-exposure prophylaxis with 2 drugs; (7) if delivery is preterm at < 34 gestational weeks, a caesarean section delivery should if possible be performed, with intravenous zidovudine and oral nevirapine given to the mother, and single-dose nevirapine given to the infant at 48-72 h of age, as well as post-exposure prophylaxis with 2 additional drugs.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
Nyckelord
- Anti-HIV Agents
- therapeutic use
- Female
- HIV Infections
- drug therapy
- prevention & control
- transmission
- Humans
- Infectious Disease Transmission
- Vertical
- prevention & control
- Post-Exposure Prophylaxis
- Practice Guidelines as Topic
- Pregnancy
- Pregnancy Complications
- Infectious
- drug therapy
- prevention & control
- Sweden
- HIV
- pregnancy
- mother-to-child transmission
- prophylaxis
- mode of
- delivery
- follow-up
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Navér, Lars
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Albert, Jan
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Böttiger, Ylva
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Carlander, Chris ...
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Flamholc, Leo
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Gisslén, Magnus, ...
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Josephson, Filip
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Karlström, Olof
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Lindborg, Lena
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Svedhem-Johansso ...
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Svennerholm, Bo
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Sönnerborg, Ande ...
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Yilmaz, Aylin, 1 ...
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Pettersson, Kari ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Infektionsmedici ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Reproduktionsmed ...
- Artiklar i publikationen
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Scandinavian jou ...
- Av lärosätet
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Göteborgs universitet
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Lunds universitet
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Karolinska Institutet