Depiction of anatomic structures of relevance for scoring of cystic fibrosis changes by chest tomosynthesis and computed tomography

• Introduction: Chest radiography (CR) and computed tomography (CT) are commonly used for imaging of patients with cystic fibrosis, and scoring is applied to assess disease severity. Chest tomosynthesis (CTS) is a new imaging modality providing better anatomic visualization than CR at radiation doses and costs lower than CT. Objective: To compare visibility and size of anatomic structures of relevance for scoring in CTS and CT images. Methods: 21 adult patients with cystic fibrosis were examined both with CTS (VolumeRAD; GE Healthcare) and volumetric CT (LightSpeed Pro 16, LightSpeed VCT, Discovery CT750HD; GE healthcare and Somatom Definition, Siemens Medical Solutions). The average effective dose for a standard patient was 0.13 and 4.5 mSv for CTS and CT, respectively. Comparison of visibility and manual measurements of diameters of the central and peripheral bronchi and their accompanying artery, as well as bronchial wall thickness (BWT), were performed in a non-blinded fashion. Results: All central structures could be evaluated. Mean difference in diameter of central bronchi, accompanying artery and BWT between CTS and CT was −0.6 (SD 0.6), −0.7 (SD 0.7) and −0.4 (SD 0.2) mm, respectively. Peripheral structures were more difficult to assess by CTS. Peripheral bronchial diameter, BWT and diameter of accompanying artery could be assessed by CTS in 20, 15 and 4 cases, respectively and mean difference between measurements was −0.5 (SD 0.5), −0.3 (SD 0.3) and −0.4 (SD 0.4) mm, respectively. Conclusion: This study indicates that peripheral structures are more difficult to evaluate by CTS and that CTS slightly underestimate size of structures in comparison to CT

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)

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