Sökning: onr:"swepub:oai:gup.ub.gu.se/245856" >
Outcome of the Swed...
Outcome of the Swedish Nationwide Abdominal Aortic Aneurysm Screening Program
-
- Wanhainen, Anders (författare)
- Uppsala universitet,Kärlkirurgi
-
- Hultgren, R. (författare)
- Karolinska Institutet
-
- Linne, A. (författare)
- Karolinska Institutet
-
visa fler...
-
- Holst, J. (författare)
- Skane Univ Hosp, Dept Vasc Dis, Malmo, Sweden
-
- Gottsater, A. (författare)
- Skane Univ Hosp, Dept Vasc Dis, Malmo, Sweden
-
- Langenskiöld, Marcus, 1972 (författare)
- Univ Gothenburg, Sahlgrenska Univ Hosp, Dept Vasc Surg, Gothenburg, Sweden
-
- Smidfelt, Kristian (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Sahlgrenska Univ Hosp, Dept Vasc Surg, Gothenburg, Sweden
-
- Björck, Martin (författare)
- Uppsala universitet,Kärlkirurgi
-
- Svensjö, Sverker (författare)
- Uppsala universitet,Kärlkirurgi,Falun Cty Hosp, Dept Surg, Falun, Sweden
-
visa färre...
-
(creator_code:org_t)
- 2016
- 2016
- Engelska.
-
Ingår i: Circulation. - 0009-7322 .- 1524-4539. ; 134:16, s. 1141-1148
- Relaterad länk:
-
https://gup.ub.gu.se...
-
visa fler...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
http://kipublication...
-
visa färre...
Abstract
Ämnesord
Stäng
- Background: A general abdominal aortic aneurysm (AAA) screening program, targeting 65-year-old men, has gradually been introduced in Sweden since 2006 and reached nationwide coverage in 2015. The aim of this study was to determine the outcome of this program. Methods: Data on the number of invited and examined men, screening-detected AAAs, AAAs operated on, and surgical outcome were retrieved from all 21 Swedish counties for the years 2006 through 2014. AAA-specific mortality data were retrieved from the Swedish Cause of Death Registry. A linear regression analysis was used to estimate the effect on AAA-specific mortality among all men 65 years of age for the observed time period. The long-term effects were projected by using a validated Markov model. Results: Of 302957 men aged 65 years invited, 84% attended. The prevalence of screening-detected AAA was 1.5%. After a mean of 4.5 years, 29% of patients with AAA had been operated on, with a 30-day mortality rate of 0.9% (1.3% after open repair and 0.3% after endovascular repair, P<0.001). The introduction of screening was associated with a significant reduction in AAA-specific mortality (mean, 4.0% per year of screening, P=0.020). The number needed to screen and the number needed to operate on to prevent 1 premature death were 667 and 1.5, respectively. With a total population of 9.5 million, the Swedish national AAA-screening program was predicted to annually prevent 90 premature deaths from AAA and to gain 577 quality-adjusted life-years. The incremental cost-efficiency ratio was estimated to be Euro7770 per quality-adjusted life-years. Conclusions: Screening 65-year-old men for AAA is an effective preventive health measure and is highly cost-effective in a contemporary setting. These findings confirm the results from earlier randomized controlled trials and model studies in a large population-based setting of the importance for future healthcare decision making.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- aneurysm
- aorta
- cost-benefit analysis
- prevention and control
- screening
- ultrasonography
- randomized controlled-trial
- mortality
- cost
- ultrasonography
- impact
- design
- repair
- life
- men
- aaa
- Cardiovascular System & Cardiology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas