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Abdominal symptoms ...
Abdominal symptoms in general practice: Frequency, cancer suspicions raised, and actions taken by GPs in six European countries. Cohort study with prospective registration of cancer
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- Holtedahl, K. (författare)
- UiT The Arctic University of Norway, Tromsø,Department of Community Medicine, UiT The Arctic University of Norway, Norway
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- Vedsted, P. (författare)
- Aarhus University, Research Unit for General Practice, Research Centre for Cancer Diagnosis in Primary Care, Denmark
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- Borgquist, Lars, 1944- (författare)
- Linköpings universitet,Linköping University,Avdelningen för samhällsmedicin,Medicinska fakulteten,Region Östergötland, Forsknings- och utvecklingsenheten för Närsjukvården i Östergötland
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- Donker, G. A. (författare)
- Netherlands Institute for Health Services Research,NIVEL Primary Care Database, Sentinel Practices, Utrecht, Netherlands
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- Buntinx, F. (författare)
- Dept of General Practice, KULeuven, Belgium, and Maastricht University, Netherlands,Catholic University of Leuven
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- Weller, D. (författare)
- Usher Institute for Population Health Sciences and Medical Informatics, The University of Edinburgh, Doorway 1, Teviot Place, Edinburgh, Scotland, UK
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- Braaten, T. (författare)
- UiT The Arctic University of Norway, Tromsø,Department of Community Medicine, UiT The Arctic University of Norway, Norway
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- Hjertholm, P. (författare)
- Aarhus University, Research Unit for General Practice, Research Centre for Cancer Diagnosis in Primary Care, Denmark
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- Månsson, Jörgen, 1958 (författare)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Department of Public Health and Community Medicine/Primary Health Care, The Sahlgrenska Academy at the University of Gothenburg, Sweden
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- Strandberg, Eva Lena (författare)
- Lund University,Lunds universitet,Allmänmedicin och samhällsmedicin,Forskargrupper vid Lunds universitet,Family Medicine and Community Medicine,Lund University Research Groups,Lund University, Department of Clinical Sciences Malmö, Family Medicine/General Practice, Sweden
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- Campbell, C. (författare)
- Usher Institute for Population Health Sciences and Medical Informatics, The University of Edinburgh, Doorway 1, Teviot Place, Edinburgh, EH8 9AG, Scotland, UK
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- Ellegaard, L. (författare)
- UiT The Arctic University of Norway, Tromsø,Department of Community Medicine, UiT The Arctic University of Norway, Norway
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- Parajuli, R. (författare)
- UiT The Arctic University of Norway, Tromsø,Department of Community Medicine, UiT The Arctic University of Norway, Norway
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- Elsevier BV, 2017
- 2017
- Engelska.
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Ingår i: Heliyon. - : Elsevier BV. - 2405-8440. ; 3:6
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Abstract
Ämnesord
Stäng
- Background Abdominal symptoms are diagnostically challenging to general practitioners (GPs): although common, they may indicate cancer. In a prospective cohort of patients, we examined abdominal symptom frequency, initial diagnostic suspicion, and actions of GPs in response to abdominal symptoms. Methods Over a 10-day period, 493 GPs in Norway, Denmark, Sweden, Belgium, the Netherlands, and Scotland, recorded consecutive consultations: sex, date of birth and any specified abdominal symptoms. For patients with abdominal symptoms, additional data on non-specific symptoms, GPs’ diagnostic suspicion, and features of the consultation were noted. Data on all cancer diagnoses among all included patients were requested from the GPs eight months later. Findings Consultations with 61802 patients were recorded. Abdominal symptoms were recorded in 6264 (10.1%) patients. A subsequent malignancy was reported in 511 patients (0.8%): 441 (86.3%) had a new cancer, 70 (13.7%) a recurrent cancer. Abdominal symptoms were noted in 129 (25.2%) of cancer patients (P < 0.001), rising to 34.5% for the 89 patients with cancer located in the abdominal region. PPV for any cancer given any abdominal symptom was 2.1%. In symptomatic patients diagnosed with cancer, GPs noted a suspicion of cancer for 85 (65.9%) versus 1895 (30.9%) when there was no subsequent cancer (P < 0.001). No suspicion was noted in 32 (24.8%) cancer patients. The GP's intuitive cancer suspicion was independently associated with a subsequent new cancer diagnosis (OR 2.11, 95% CI 1.15–3.89). Laboratory tests were ordered for 45.4% of symptomatic patients, imaging for 10.4%, referral or hospitalization for 20.0%: all were more frequent in subsequent cancer patients (P < 0.001). Interpretation Abdominal symptoms pointed to abdominal cancers rather than to other cancers. However, the finding of abdominal symptoms in only one third of patients with an abdominal cancer, and the lack of cancer suspicion in a quarter of symptomatic cancer patients, provide challenges for GPs’ diagnostic thinking and referral practices. © 2017 The Authors
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Allmänmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- General Practice (hsv//eng)
Nyckelord
- Evidence-based medicine
- Medicine
- Oncology
- Public health
- Evidence-based medicine; Medicine; Oncology; Public health
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Holtedahl, K.
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Vedsted, P.
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Borgquist, Lars, ...
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Donker, G. A.
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Buntinx, F.
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Weller, D.
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Braaten, T.
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Hjertholm, P.
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Månsson, Jörgen, ...
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Strandberg, Eva ...
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Campbell, C.
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Ellegaard, L.
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Parajuli, R.
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- MEDICIN OCH HÄLSOVETENSKAP
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