Sökning: onr:"swepub:oai:gup.ub.gu.se/266265" > Twelve-lead electro...
Fältnamn | Indikatorer | Metadata |
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000 | 03714naa a2200457 4500 | |
001 | oai:gup.ub.gu.se/266265 | |
003 | SwePub | |
008 | 240910s2017 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/2662652 URI |
024 | 7 | a https://doi.org/10.1177/23969873166847062 DOI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Pirinen, Jani4 aut |
245 | 1 0 | a Twelve-lead electrocardiogram and mortality in young adults after ischaemic stroke |
264 | c 2016-12-14 | |
264 | 1 | b SAGE Publications,c 2017 |
520 | a Introduction: Ischaemic stroke at young age carries an increased risk for mortality in comparison to the general population, but factors associated with mortality have been poorly studied. We studied the role of electrocardiogram in mortality risk stratification in young stroke patients. Patients and methods: The Helsinki Young Stroke Registry encompasses 1008 patients aged <50 years with ischaemic stroke. We included 690 patients for this electrocardiogram substudy. Our endpoints were all-cause and cardiovascular mortality. Cox regression models – adjusted for clinical and demographic characteristics – were used to identify the electrocardiogram parameters associated with these endpoints. Results: At a mean follow-up of 8.8 years, cumulative all-cause and cardiovascular mortality were 16.1 and 9.1%, respectively. Factors associated with both endpoints included diabetes (type 1 for all-cause, type 2 for cardiovascular mortality), heavy drinking, malignancy, as well as stroke severity and aetiology. Of the electrocardiogram parameters, higher heart rate (hazard ratio 1.35 per 10/min, 95% confidence interval 1.21–1.49), a shorter P-wave (hazard ratio 0.78 per 10 ms decrement, 0.64–0.92) and longer QTc interval (1.09 per 10 ms, 1.03–1.16) were associated with increased all-cause mortality. Only a higher heart rate (1.42 per 10/min, 1.24–1.60) was associated with death from cardiovascular causes. Conclusions: A higher heart rate during the subacute phase after stroke is associated with an elevated risk of all-cause and cardiovascular mortality in young adults. A longer QTc interval is associated only with higher all-cause mortality. P-wave characteristics and their possible association with mortality need further studies. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng |
653 | a Electrocardiogram | |
653 | a stroke | |
653 | a young stroke | |
653 | a prognosis | |
653 | a mortality | |
700 | 1 | a Putaala, Jukka4 aut |
700 | 1 | a Aarnio, Karoliina4 aut |
700 | 1 | a Aro, Aapo L4 aut |
700 | 1 | a Mustanoja, Satu4 aut |
700 | 1 | a Sinisalo, Juha4 aut |
700 | 1 | a Kaste, Markku4 aut |
700 | 1 | a Haapaniemi, Elena4 aut |
700 | 1 | a Tatlisumak, Turgutu Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience4 aut0 (Swepub:gu)xtatlt |
700 | 1 | a Lehto, Mika4 aut |
710 | 2 | a Göteborgs universitetb Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap4 org |
773 | 0 | t European Stroke Journald : SAGE Publicationsg 2:1, s. 77-86q 2:1<77-86x 2396-9873x 2396-9881 |
856 | 4 | u https://journals.sagepub.com/doi/pdf/10.1177/2396987316684706 |
856 | 4 8 | u https://gup.ub.gu.se/publication/266265 |
856 | 4 8 | u https://doi.org/10.1177/2396987316684706 |
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