Sökning: onr:"swepub:oai:gup.ub.gu.se/268397" > Rare and Common Var...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 04327naa a2200925 4500 | |
001 | oai:gup.ub.gu.se/268397 | |
003 | SwePub | |
008 | 240528s2018 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/2683972 URI |
024 | 7 | a https://doi.org/10.1177/00220345177501092 DOI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Jonsson, Lina,d 1982u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för farmakologi,Institute of Neuroscience and Physiology, Department of Pharmacology4 aut0 (Swepub:gu)xjliny |
245 | 1 0 | a Rare and Common Variants Conferring Risk of Tooth Agenesis |
264 | c 2018-01-24 | |
264 | 1 | b SAGE Publications,c 2018 |
520 | a We present association results from a large genome-wide association study of tooth agenesis (TA) as well as selective TA, including 1,944 subjects with congenitally missing teeth, excluding third molars, and 338,554 controls, all of European ancestry. We also tested the association of previously identified risk variants, for timing of tooth eruption and orofacial clefts, with TA. We report associations between TA and 9 novel risk variants. Five of these variants associate with selective TA, including a variant conferring risk of orofacial clefts. These results contribute to a deeper understanding of the genetic architecture of tooth development and disease. The few variants previously associated with TA were uncovered through candidate gene studies guided by mouse knockouts. Knowing the etiology and clinical features of TA is important for planning oral rehabilitation that often involves an interdisciplinary approach. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Odontologi0 (SwePub)302162 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Dentistry0 (SwePub)302162 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng |
653 | a genetics | |
653 | a molecular genetics | |
653 | a hypodontia | |
653 | a oligodontia | |
653 | a orofacial cleft(s) | |
653 | a odontogenesis | |
653 | a genome-wide association | |
653 | a 3rd molar agenesis | |
653 | a ectodermal dysplasia | |
653 | a lateral incisor | |
653 | a permanent teeth | |
653 | a ectodysplasin-a | |
653 | a cleft-lip | |
653 | a prevalence | |
653 | a mutation | |
653 | a metaanalysis | |
700 | 1 | a Magnusson, T. E.4 aut |
700 | 1 | a Thordarson, A.4 aut |
700 | 1 | a Jonsson, T.4 aut |
700 | 1 | a Geller, F.4 aut |
700 | 1 | a Feenstra, B.4 aut |
700 | 1 | a Melbye, M.4 aut |
700 | 1 | a Nohr, E. A.4 aut |
700 | 1 | a Vucic, S.4 aut |
700 | 1 | a Dhamo, B.4 aut |
700 | 1 | a Rivadeneira, F.4 aut |
700 | 1 | a Ongkosuwito, E. M.4 aut |
700 | 1 | a Wolvius, E. B.4 aut |
700 | 1 | a Leslie, E. J.4 aut |
700 | 1 | a Marazita, M. L.4 aut |
700 | 1 | a Howe, B. J.4 aut |
700 | 1 | a Uribe, L. M. M.4 aut |
700 | 1 | a Alonso, I.4 aut |
700 | 1 | a Santos, M.4 aut |
700 | 1 | a Pinho, T.4 aut |
700 | 1 | a Jonsson, R.4 aut |
700 | 1 | a Audolfsson, G.4 aut |
700 | 1 | a Gudmundsson, L.4 aut |
700 | 1 | a Nawaz, M. S.4 aut |
700 | 1 | a Olafsson, S.4 aut |
700 | 1 | a Gustafsson, O.4 aut |
700 | 1 | a Ingason, A.4 aut |
700 | 1 | a Unnsteinsdottir, U.4 aut |
700 | 1 | a Bjornsdottir, G.4 aut |
700 | 1 | a Walters, G. B.4 aut |
700 | 1 | a Zervas, M.4 aut |
700 | 1 | a Oddsson, A.4 aut |
700 | 1 | a Gudbjartsson, D. F.4 aut |
700 | 1 | a Steinberg, S.4 aut |
700 | 1 | a Stefansson, H.4 aut |
700 | 1 | a Stefansson, K.4 aut |
710 | 2 | a Göteborgs universitetb Institutionen för neurovetenskap och fysiologi, sektionen för farmakologi4 org |
773 | 0 | t Journal of Dental Researchd : SAGE Publicationsg 97:5, s. 515-522q 97:5<515-522x 0022-0345x 1544-0591 |
856 | 4 | u https://europepmc.org/articles/pmc5958369?pdf=render |
856 | 4 8 | u https://gup.ub.gu.se/publication/268397 |
856 | 4 8 | u https://doi.org/10.1177/0022034517750109 |
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.