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Taste reactivity to...
Taste reactivity to ethanol in rats: Influence of adrenalectomy or ipsapirone
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- Fahlke, Claudia, 1964 (författare)
- Gothenburg University,Göteborgs universitet,Psykologiska institutionen,Department of Psychology
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Thomasson, Rosita (författare)
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Hard, Ernest (författare)
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Engel, Jörgen A. (författare)
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Hansen, Stefan (författare)
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(creator_code:org_t)
- Elsevier BV, 1994
- 1994
- Engelska.
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Ingår i: Alcohol. - : Elsevier BV. - 0741-8329. ; 11, s. 289-294
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The affective mimetic responses of male Wistar rats with prior access to 6% ethanol in their home cages were observed during intraoral infusions of an equivalent alcohol solution. Ethanol preference in the home cage appeared unrelated to measures of aversion and ingestion in the taste reactivity tests in normal rats. Adrenalectomy, which significantly reduced home cage ethanol preference, failed to influence the taste reactions elicited by ethanol or water. On the other hand, treatment of intact rats with the 5-HT1Areceptor agonist ipsapirone (2.5 mg/kg), a drug that also decreases ethanol drinking in two-bottle intake tests, did increase the duration of aversive groomings, whereas measures of ingestion remained unaffected. These results suggest that ipsapirone, but not adrenalectomy, may alter the palatibility of ethanol; this perceptual change may partly underlie the ability of ipsapirone to reduce home cage alcohol drinking in the rat. © 1994.
Ämnesord
- SAMHÄLLSVETENSKAP -- Psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology (hsv//eng)
Nyckelord
- 5-HT agonist Gustatory reactions 1A
- Adrenalectomy
- Alcohol drinking
- Corticosterone
- Ipsapirone
- Taste reactivity
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Alcohol
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