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Components in Lenti...
Components in Lentinus edodes mushroom with anti-biofilm activity directed against bacteria involved in caries and gingivitis
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Papetti, A. (författare)
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Signoretto, C. (författare)
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Spratt, D. A. (författare)
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Pratten, J. (författare)
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- Lingström, Peter, 1960 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
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Zaura, E. (författare)
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Ofek, I. (författare)
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Wilson, M. (författare)
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Pruzzo, C. (författare)
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Gazzani, G. (författare)
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(creator_code:org_t)
- 2018
- 2018
- Engelska.
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Ingår i: Food & Function. - : Royal Society of Chemistry (RSC). - 2042-6496 .- 2042-650X. ; 9:6, s. 3489-3499
- Relaterad länk:
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https://discovery.uc...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The present study investigated the compounds present in the low molecular mass fraction of Lentinus edodes mushroom (shiitake) extract and their anti-virulence activity against oral pathogens (reference and clinical Streptococcus mutans, Actinomyces naeslundii, and Prevotella intermedia strains). Oxalic, succinic, and quinic acids, and adenine, inosine, and uridine were identified by HPLC-DAD-ESI-MS/MS. Their anti-biofilm production and preformed biofilm disaggregation activities were studied using commercial standard compounds at different concentrations. As regards S. mutans, the highest activity was shown by adenine at 5 mg mL(-1) both in the biofilm inhibition (BI 50%) and biofilm disaggregation tests (BD 20%). Considering A. naeslundii, BI values close to 80% were registered for oxalic acid at 1 mg mL(-1) and 2 mg mL(-1) and BD 50% for quinic acid at 3 mg mL(-1). A weaker activity was found against P. intermedia. Furthermore, different mixtures of the commercial standards were tested showing that the activity of a compound can be strongly and sometimes negatively affected by the presence of the other compounds.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Nyckelord
- edible mushroom
- organic-acids
- antibacterial activity
- antimicrobial
- activity
- antioxidant activities
- liquid-chromatography
- quantitative-analyses
- cultivated mushrooms
- pathogenic bacteria
- antitumor-activity
- Biochemistry & Molecular Biology
- Food Science & Technology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Papetti, A.
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Signoretto, C.
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Spratt, D. A.
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Pratten, J.
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Lingström, Peter ...
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Zaura, E.
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visa fler...
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Ofek, I.
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Wilson, M.
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Pruzzo, C.
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Gazzani, G.
-
visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Odontologi
- Artiklar i publikationen
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Food & Function
- Av lärosätet
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Göteborgs universitet