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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04372naa a2200457 4500 | |
| 001 | oai:gup.ub.gu.se/270400 | |
| 003 | SwePub | |
| 008 | 240910s2018 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://gup.ub.gu.se/publication/2704002 URI |
| 024 | 7 | a https://doi.org/10.1038/s41395-018-0074-z2 DOI |
| 040 | a (SwePub)gu | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Aziz, Imranu Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition4 aut0 (Swepub:gu)xaziim |
| 245 | 1 0 | a How the Change in IBS Criteria From Rome III to Rome IV Impacts on Clinical Characteristics and Key Pathophysiological Factors |
| 264 | 1 | b Ovid Technologies (Wolters Kluwer Health),c 2018 |
| 520 | a OBJECTIVES: The diagnostic criteria for irritable bowel syndrome (IBS) have recently been updated from Rome III to Rome IV. Whereas in Rome III a diagnosis of IBS entailed chronic abdominal pain or discomfort at least 3 days per month, in Rome IV the term discomfort has been removed and the frequency of abdominal pain increased to at least 1 day per week. We examined how this change in IBS criteria impacts on clinical characteristics and pathophysiological factors. METHODS: A total of 542 Swedish subjects with Rome III IBS completed a baseline questionnaire enquiring for the number of abdominal pain days in the last 10 days; this was subsequently used as a surrogate marker to identify Rome IV IBS, in that (a) those with 0 or 1 day of pain were classed as Rome IV-negative, and (b) those with >= 2 days of pain were classed as Rome IV-positive. Comparisons were made between Rome IV-positive and -negative IBS groups for demographics, IBS subtype, gastrointestinal and psychological symptoms, somatisation, fatigue, disease-specific quality of life, rectal sensitivity, and oro-anal transit time. RESULTS: Overall, 85% of Rome III IBS patients fulfilled the Rome IV criteria for IBS, but 15% did not. Rome IV-positive subjects were significantly more likely to be female, have poorer quality of life, greater pain severity, bloating, somatisation, fatigue, and rectal sensitivity than Rome IV-negative subjects. There were no differences in severity of anxiety or depression, IBS subtypes, bowel habit dissatisfaction, or oro-anal transit time. Finally, increasing number of pain days correlated positively with symptoms and visceral hypersensitivity. CONCLUSIONS: Most Rome III-positive IBS patients seeking healthcare fulfil the Rome IV IBS criteria. They constitute a more severe group than those who lose their IBS diagnosis. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng |
| 653 | a irritable-bowel-syndrome | |
| 653 | a quality-of-life | |
| 653 | a cross-sectional survey | |
| 653 | a transit-time | |
| 653 | a symptoms | |
| 653 | a scale | |
| 653 | a questionnaire | |
| 653 | a metaanalysis | |
| 653 | a prevalence | |
| 653 | a severity | |
| 653 | a Gastroenterology & Hepatology | |
| 700 | 1 | a Törnblom, Hans,d 1966u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition4 aut0 (Swepub:gu)xtornh |
| 700 | 1 | a Palsson, O. S.4 aut |
| 700 | 1 | a Whitehead, W. E.4 aut |
| 700 | 1 | a Simrén, Magnus,d 1966u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition4 aut0 (Swepub:gu)xsimrm |
| 710 | 2 | a Göteborgs universitetb Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition4 org |
| 773 | 0 | t American Journal of Gastroenterologyd : Ovid Technologies (Wolters Kluwer Health)g 113:7, s. 1017-1025q 113:7<1017-1025x 0002-9270 |
| 856 | 4 | u https://cdr.lib.unc.edu/downloads/6t053n51g |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/270400 |
| 856 | 4 8 | u https://doi.org/10.1038/s41395-018-0074-z |
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